TY - JOUR

T1 - Aluminium salt-based antiperspirant coated prosthesis liners do not suppress local sweating during moderate intensity exercise in hot and temperate conditions

AU - Morris, Nathan Bradley

AU - Jay, Ollie

N1 - CURIS 2020 NEXS 203

PY - 2020

Y1 - 2020

N2 - Objective: To determine whether coating prosthesis liners with a 5% aluminium zirconium tetrachlorohydrate antiperspirant solution (AZCH) reduces local sweating on the thigh. Design: Double-blinded counter-balanced crossover design Methods: Fourteen able-bodied participants (age: 28 ± 5 y; body mass: 73.9 ± 7.9 kg, height: 1.73 ± 0.09 m; peak oxygen consumption [VO2peak]: 50.7 ± 9.1 mlO2⋅ kg−1⋅ min−1) simultaneously wore a prosthesis liner on each leg, one treated with AZCH and one untreated, for four days prior to running at 50% of VO2peak for 60 min in a temperate (23.7 ± 0.7 °C and 42.2 ± 2.6% relative humidity) or hot (34.0 ± 1.6 °C and 40.8 ± 6.1% relative humidity) environment. Rectal temperature (Tre) and whole-body sweat rates (WBSR) were measured to characterize thermal strain. Local sweat rate (LSR) was measured bilaterally underneath the liners, continuously, and heat-activated-sweat gland density (HASGD) was measured bilaterally every 15 min. Results: In temperate condition, the mean change in Tre was 1.2±0.4 °C and WBSR was 723 ± 129 g⋅ h−1, whereas in the hot condition, change in Tre was 1.2±0.5 °C and WBSR was 911 ± 231 g⋅ h−1. In the temperate condition, AZCH treatment did not alter LSR (treated: 0.50±0.17 mg·cm–2 min–1, untreated: 0.50±0.17 mg·cm–2 min–1; P = 0.87) or HASGD (treated: 54±14 glands·cm–2, untreated 55±14 glands·cm–2; P = 0.38). In the hot condition, AZCH treatment paradoxically increased LSR (treated: 0.88 ± 0.38 mg·cm–2 min–1, untreated: 0.74 ± 0.28 mg·cm–2 min–1; P = 0.04) but not HASGD (treated: 52 ± 17 glands·cm–2, untreated: 48 ± 19 glands·cm–2; P = 0.77).Conclusion: These results indicate coating prosthesis liners with 5% AZCH is ineffective at reducing local sweating.

AB - Objective: To determine whether coating prosthesis liners with a 5% aluminium zirconium tetrachlorohydrate antiperspirant solution (AZCH) reduces local sweating on the thigh. Design: Double-blinded counter-balanced crossover design Methods: Fourteen able-bodied participants (age: 28 ± 5 y; body mass: 73.9 ± 7.9 kg, height: 1.73 ± 0.09 m; peak oxygen consumption [VO2peak]: 50.7 ± 9.1 mlO2⋅ kg−1⋅ min−1) simultaneously wore a prosthesis liner on each leg, one treated with AZCH and one untreated, for four days prior to running at 50% of VO2peak for 60 min in a temperate (23.7 ± 0.7 °C and 42.2 ± 2.6% relative humidity) or hot (34.0 ± 1.6 °C and 40.8 ± 6.1% relative humidity) environment. Rectal temperature (Tre) and whole-body sweat rates (WBSR) were measured to characterize thermal strain. Local sweat rate (LSR) was measured bilaterally underneath the liners, continuously, and heat-activated-sweat gland density (HASGD) was measured bilaterally every 15 min. Results: In temperate condition, the mean change in Tre was 1.2±0.4 °C and WBSR was 723 ± 129 g⋅ h−1, whereas in the hot condition, change in Tre was 1.2±0.5 °C and WBSR was 911 ± 231 g⋅ h−1. In the temperate condition, AZCH treatment did not alter LSR (treated: 0.50±0.17 mg·cm–2 min–1, untreated: 0.50±0.17 mg·cm–2 min–1; P = 0.87) or HASGD (treated: 54±14 glands·cm–2, untreated 55±14 glands·cm–2; P = 0.38). In the hot condition, AZCH treatment paradoxically increased LSR (treated: 0.88 ± 0.38 mg·cm–2 min–1, untreated: 0.74 ± 0.28 mg·cm–2 min–1; P = 0.04) but not HASGD (treated: 52 ± 17 glands·cm–2, untreated: 48 ± 19 glands·cm–2; P = 0.77).Conclusion: These results indicate coating prosthesis liners with 5% AZCH is ineffective at reducing local sweating.

KW - Amputation

KW - Amputee

KW - Compensatory hyperhidrosis

KW - Paralympic sport

KW - Residual limb hyperhidrosis

UR - http://www.scopus.com/inward/record.url?scp=85085620145&partnerID=8YFLogxK

U2 - 10.1016/j.jsams.2020.05.012

DO - 10.1016/j.jsams.2020.05.012

M3 - Journal article

C2 - 32482611

AN - SCOPUS:85085620145

VL - 23

SP - 1128

EP - 1133

JO - Journal of Science and Medicine in Sport

JF - Journal of Science and Medicine in Sport

SN - 1440-2440

IS - 12

ER -