Aluminium salt-based antiperspirant coated prosthesis liners do not suppress local sweating during moderate intensity exercise in hot and temperate conditions

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Objective: To determine whether coating prosthesis liners with a 5% aluminium zirconium tetrachlorohydrate antiperspirant solution (AZCH) reduces local sweating on the thigh. 

Design: Double-blinded counter-balanced crossover design Methods: Fourteen able-bodied participants (age: 28 ± 5 y; body mass: 73.9 ± 7.9 kg, height: 1.73 ± 0.09 m; peak oxygen consumption [VO2peak]: 50.7 ± 9.1 mlO2⋅ kg−1⋅ min−1) simultaneously wore a prosthesis liner on each leg, one treated with AZCH and one untreated, for four days prior to running at 50% of VO2peak for 60 min in a temperate (23.7 ± 0.7 °C and 42.2 ± 2.6% relative humidity) or hot (34.0 ± 1.6 °C and 40.8 ± 6.1% relative humidity) environment. Rectal temperature (Tre) and whole-body sweat rates (WBSR) were measured to characterize thermal strain. Local sweat rate (LSR) was measured bilaterally underneath the liners, continuously, and heat-activated-sweat gland density (HASGD) was measured bilaterally every 15 min. 

Results: In temperate condition, the mean change in Tre was 1.2±0.4 °C and WBSR was 723 ± 129 g⋅ h−1, whereas in the hot condition, change in Tre was 1.2±0.5 °C and WBSR was 911 ± 231 g⋅ h−1. In the temperate condition, AZCH treatment did not alter LSR (treated: 0.50±0.17 mg·cm–2 min–1, untreated: 0.50±0.17 mg·cm–2 min–1; P = 0.87) or HASGD (treated: 54±14 glands·cm–2, untreated 55±14 glands·cm–2; P = 0.38). In the hot condition, AZCH treatment paradoxically increased LSR (treated: 0.88 ± 0.38 mg·cm–2 min–1, untreated: 0.74 ± 0.28 mg·cm–2 min–1; P = 0.04) but not HASGD (treated: 52 ± 17 glands·cm–2, untreated: 48 ± 19 glands·cm–2; P = 0.77).

Conclusion: These results indicate coating prosthesis liners with 5% AZCH is ineffective at reducing local sweating.

OriginalsprogEngelsk
TidsskriftJournal of Science and Medicine in Sport
ISSN1440-2440
DOI
StatusE-pub ahead of print - 17 maj 2020

Bibliografisk note

CURIS 2020 NEXS 203

ID: 243346540