The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo. / Verhagen, H.; Aruoma, O.I.; van Delft, J.H.M.; Dragsted, Lars Ove; Ferguson, L.R.; Knasmüller, S.; Pool-Zobel, B.L.; Poulsen, H.E.; Williamson, G.; Yannai, S.

I: Food and Chemical Toxicology, Bind 41, Nr. 5, 2003, s. 603-610.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Verhagen, H, Aruoma, OI, van Delft, JHM, Dragsted, LO, Ferguson, LR, Knasmüller, S, Pool-Zobel, BL, Poulsen, HE, Williamson, G & Yannai, S 2003, 'The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo', Food and Chemical Toxicology, bind 41, nr. 5, s. 603-610. https://doi.org/10.1016/S0278-6915(03)00025-5

APA

Verhagen, H., Aruoma, O. I., van Delft, J. H. M., Dragsted, L. O., Ferguson, L. R., Knasmüller, S., Pool-Zobel, B. L., Poulsen, H. E., Williamson, G., & Yannai, S. (2003). The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo. Food and Chemical Toxicology, 41(5), 603-610. https://doi.org/10.1016/S0278-6915(03)00025-5

Vancouver

Verhagen H, Aruoma OI, van Delft JHM, Dragsted LO, Ferguson LR, Knasmüller S o.a. The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo. Food and Chemical Toxicology. 2003;41(5):603-610. https://doi.org/10.1016/S0278-6915(03)00025-5

Author

Verhagen, H. ; Aruoma, O.I. ; van Delft, J.H.M. ; Dragsted, Lars Ove ; Ferguson, L.R. ; Knasmüller, S. ; Pool-Zobel, B.L. ; Poulsen, H.E. ; Williamson, G. ; Yannai, S. / The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo. I: Food and Chemical Toxicology. 2003 ; Bind 41, Nr. 5. s. 603-610.

Bibtex

@article{8ab1a869bf484a30885b27500e7a9261,
title = "The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo",
abstract = "There is increasing evidence that chemicals/test substances cannot only have adverse effects, but that there are many substances that can (also) have a beneficial effect on health. As this journal regularly publishes papers in this area and has every intention in continuing to do so in the near future, it has become essential that studies reported in this journal reflect an adequate level of scientific scrutiny. Therefore a set of essential characteristics of studies has been defined. These basic requirements are default properties rather than non-negotiables: deviations are possible and useful, provided they can be justified on scientific grounds. The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo concern the following areas: (1) Hypothesis-driven study design; (2) The nature of the test substance; (3) Valid and invalid test systems; (4) The selection of dose levels and gender; (5) Reversal of the effects induced by oxidants, carcinogens and mutagens; (6) Route of administration; (7) Number and validity of test variables; (8) Repeatability and reproducibility; (9) Statistics; and (10) Quality Assurance.",
keywords = "Faculty of Science, Requirements, Antioxidant, Antimutagenic, Anticarcinogenic",
author = "H. Verhagen and O.I. Aruoma and {van Delft}, J.H.M. and Dragsted, {Lars Ove} and L.R. Ferguson and S. Knasm{\"u}ller and B.L. Pool-Zobel and H.E. Poulsen and G. Williamson and S. Yannai",
note = "(Ekstern)",
year = "2003",
doi = "10.1016/S0278-6915(03)00025-5",
language = "English",
volume = "41",
pages = "603--610",
journal = "Food and Chemical Toxicology",
issn = "0278-6915",
publisher = "Pergamon Press",
number = "5",

}

RIS

TY - JOUR

T1 - The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo

AU - Verhagen, H.

AU - Aruoma, O.I.

AU - van Delft, J.H.M.

AU - Dragsted, Lars Ove

AU - Ferguson, L.R.

AU - Knasmüller, S.

AU - Pool-Zobel, B.L.

AU - Poulsen, H.E.

AU - Williamson, G.

AU - Yannai, S.

N1 - (Ekstern)

PY - 2003

Y1 - 2003

N2 - There is increasing evidence that chemicals/test substances cannot only have adverse effects, but that there are many substances that can (also) have a beneficial effect on health. As this journal regularly publishes papers in this area and has every intention in continuing to do so in the near future, it has become essential that studies reported in this journal reflect an adequate level of scientific scrutiny. Therefore a set of essential characteristics of studies has been defined. These basic requirements are default properties rather than non-negotiables: deviations are possible and useful, provided they can be justified on scientific grounds. The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo concern the following areas: (1) Hypothesis-driven study design; (2) The nature of the test substance; (3) Valid and invalid test systems; (4) The selection of dose levels and gender; (5) Reversal of the effects induced by oxidants, carcinogens and mutagens; (6) Route of administration; (7) Number and validity of test variables; (8) Repeatability and reproducibility; (9) Statistics; and (10) Quality Assurance.

AB - There is increasing evidence that chemicals/test substances cannot only have adverse effects, but that there are many substances that can (also) have a beneficial effect on health. As this journal regularly publishes papers in this area and has every intention in continuing to do so in the near future, it has become essential that studies reported in this journal reflect an adequate level of scientific scrutiny. Therefore a set of essential characteristics of studies has been defined. These basic requirements are default properties rather than non-negotiables: deviations are possible and useful, provided they can be justified on scientific grounds. The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo concern the following areas: (1) Hypothesis-driven study design; (2) The nature of the test substance; (3) Valid and invalid test systems; (4) The selection of dose levels and gender; (5) Reversal of the effects induced by oxidants, carcinogens and mutagens; (6) Route of administration; (7) Number and validity of test variables; (8) Repeatability and reproducibility; (9) Statistics; and (10) Quality Assurance.

KW - Faculty of Science

KW - Requirements

KW - Antioxidant

KW - Antimutagenic

KW - Anticarcinogenic

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-0037401333&partnerID=MN8TOARS

U2 - 10.1016/S0278-6915(03)00025-5

DO - 10.1016/S0278-6915(03)00025-5

M3 - Journal article

VL - 41

SP - 603

EP - 610

JO - Food and Chemical Toxicology

JF - Food and Chemical Toxicology

SN - 0278-6915

IS - 5

ER -

ID: 273754284