Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a PET study with nitric oxide and cyclooxygenase inhibition

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Standard

Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a PET study with nitric oxide and cyclooxygenase inhibition. / Heinonen, Ilkka; Saltin, Bengt; Kemppainen, Jukka; Sipilä, Hannu T; Oikonen, Vesa; Nuutila, Pirjo; Knuuti, Juhani; Kalliokoski, Kari; Hellsten, Ylva.

I: American Journal of Physiology: Heart and Circulatory Physiology, Bind 300, Nr. 4, 2011, s. H1510-H1517.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Heinonen, I, Saltin, B, Kemppainen, J, Sipilä, HT, Oikonen, V, Nuutila, P, Knuuti, J, Kalliokoski, K & Hellsten, Y 2011, 'Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a PET study with nitric oxide and cyclooxygenase inhibition', American Journal of Physiology: Heart and Circulatory Physiology, bind 300, nr. 4, s. H1510-H1517. https://doi.org/10.1152/ajpheart.00996.2010

APA

Heinonen, I., Saltin, B., Kemppainen, J., Sipilä, H. T., Oikonen, V., Nuutila, P., Knuuti, J., Kalliokoski, K., & Hellsten, Y. (2011). Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a PET study with nitric oxide and cyclooxygenase inhibition. American Journal of Physiology: Heart and Circulatory Physiology, 300(4), H1510-H1517. https://doi.org/10.1152/ajpheart.00996.2010

Vancouver

Heinonen I, Saltin B, Kemppainen J, Sipilä HT, Oikonen V, Nuutila P o.a. Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a PET study with nitric oxide and cyclooxygenase inhibition. American Journal of Physiology: Heart and Circulatory Physiology. 2011;300(4):H1510-H1517. https://doi.org/10.1152/ajpheart.00996.2010

Author

Heinonen, Ilkka ; Saltin, Bengt ; Kemppainen, Jukka ; Sipilä, Hannu T ; Oikonen, Vesa ; Nuutila, Pirjo ; Knuuti, Juhani ; Kalliokoski, Kari ; Hellsten, Ylva. / Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a PET study with nitric oxide and cyclooxygenase inhibition. I: American Journal of Physiology: Heart and Circulatory Physiology. 2011 ; Bind 300, Nr. 4. s. H1510-H1517.

Bibtex

@article{bbf9f0ad6d3840d4823108f4525b83cb,
title = "Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a PET study with nitric oxide and cyclooxygenase inhibition",
abstract = "The aim of the present study was to determine the effect of nitric oxide and prostanoids on microcirculation and oxygen uptake specifically in the active skeletal muscle by use of positron emission tomography (PET). Healthy males performed 3 five min bouts of light knee-extensor exercise. Skeletal muscle blood flow and oxygen uptake were measured at rest and during the exercise using PET with H(2)O(15) and (15)O(2) during: 1) control conditions; 2) nitric oxide synthase (NOS) inhibition by arterial infusion of L-NMMA and 3) combined NOS and cyclooxygenase (COX) inhibition by arterial infusion of L-NMMA and indomethacin. At rest, inhibition of NOS alone and in combination with indomethacin reduced (P",
author = "Ilkka Heinonen and Bengt Saltin and Jukka Kemppainen and Sipil{\"a}, {Hannu T} and Vesa Oikonen and Pirjo Nuutila and Juhani Knuuti and Kari Kalliokoski and Ylva Hellsten",
note = "CURIS 2011 5200 017",
year = "2011",
doi = "10.1152/ajpheart.00996.2010",
language = "English",
volume = "300",
pages = "H1510--H1517",
journal = "American Journal of Physiology: Heart and Circulatory Physiology",
issn = "0363-6135",
publisher = "American Physiological Society",
number = "4",

}

RIS

TY - JOUR

T1 - Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a PET study with nitric oxide and cyclooxygenase inhibition

AU - Heinonen, Ilkka

AU - Saltin, Bengt

AU - Kemppainen, Jukka

AU - Sipilä, Hannu T

AU - Oikonen, Vesa

AU - Nuutila, Pirjo

AU - Knuuti, Juhani

AU - Kalliokoski, Kari

AU - Hellsten, Ylva

N1 - CURIS 2011 5200 017

PY - 2011

Y1 - 2011

N2 - The aim of the present study was to determine the effect of nitric oxide and prostanoids on microcirculation and oxygen uptake specifically in the active skeletal muscle by use of positron emission tomography (PET). Healthy males performed 3 five min bouts of light knee-extensor exercise. Skeletal muscle blood flow and oxygen uptake were measured at rest and during the exercise using PET with H(2)O(15) and (15)O(2) during: 1) control conditions; 2) nitric oxide synthase (NOS) inhibition by arterial infusion of L-NMMA and 3) combined NOS and cyclooxygenase (COX) inhibition by arterial infusion of L-NMMA and indomethacin. At rest, inhibition of NOS alone and in combination with indomethacin reduced (P

AB - The aim of the present study was to determine the effect of nitric oxide and prostanoids on microcirculation and oxygen uptake specifically in the active skeletal muscle by use of positron emission tomography (PET). Healthy males performed 3 five min bouts of light knee-extensor exercise. Skeletal muscle blood flow and oxygen uptake were measured at rest and during the exercise using PET with H(2)O(15) and (15)O(2) during: 1) control conditions; 2) nitric oxide synthase (NOS) inhibition by arterial infusion of L-NMMA and 3) combined NOS and cyclooxygenase (COX) inhibition by arterial infusion of L-NMMA and indomethacin. At rest, inhibition of NOS alone and in combination with indomethacin reduced (P

U2 - 10.1152/ajpheart.00996.2010

DO - 10.1152/ajpheart.00996.2010

M3 - Journal article

C2 - 21257921

VL - 300

SP - H1510-H1517

JO - American Journal of Physiology: Heart and Circulatory Physiology

JF - American Journal of Physiology: Heart and Circulatory Physiology

SN - 0363-6135

IS - 4

ER -

ID: 32904790