Background: Short term physical training programs may improve insulin resistance and hyperglycemia. 

Aim: To assess the effects of eight weeks of combined exercise program on serum lipids and glycemic level in women with hyperglycemia and hypercholesterolemia. 

Patients and Methods: Ten healthy women, nine women with hyperglycemia, ten with hypercholesterolemia and nine with hyperglycemia/hypercholesterolemia were studied. Participants were subjected to eight weeks into a program of combined physical exercise (high intensity interval + resistance training). 

Results: Fasting glycemia decreased by 12 and 14% in hyperglycemic and hyperglycemic/hypercholesterolemic participants, respectively. Serum insulin decreased in all groups in a range from 27 to 37%. HOMA_IR for insulin resistance decreased similarly. A significant decrease in TC and TG was observed only in those altered baseline subjects. 

Conclusions: Eight weeks of combined physical exercise had a favorable effect on insulin resistance in this group of women.