Let's get aligned! Developing a core outcome set for clinical trials in eating disorders

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

  • Anna Victoria Brieva-Toloza
  • Oliver Rumle Hovmand
  • Micali, Nadia
  • Anne Bryde Christensen
Objective
Our study aimed to review the outcome measures/assessment instruments used and to assess their heterogeneity/homogeneity in eating disorders (EDs) randomised controlled trials.

Methods
APA PsycInfo, PubMed, and Embase were searched in December 2022 to identify studies published between and inclusive of January 2012 and December 2022. Inclusion/exclusion criteria were: (1) complete articles published in peer-reviewed scientific journals, which were: (2) randomised trials, (3) in a clinical setting (4) with human subjects, (5) with an ICD or DSM diagnosis of Anorexia Nervosa, Binge Eating Disorder, or Bulimia Nervosa. The selected papers also: (6) used one or more standardised instruments designed to measure one or more psychometric characteristics associated with ED as a primary or secondary outcome, as judged by the authors of this systematic review, and (7) were published in English or Danish.

Results
Ninety one articles were included, and a total of 196 outcome measures were collected.

Discussion
The diversity of outcome measures in ED trials hampers result comparability and data integration. We suggest creating a core outcome measure set using the Delphi method, including clinician and patient-reported ED assessments, along with relevant comorbidity scales.
OriginalsprogEngelsk
TidsskriftEuropean Eating Disorders Review
Antal sider10
ISSN1072-4133
DOI
StatusE-pub ahead of print - 2024

Bibliografisk note

© 2024 The Authors. European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.

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