Cross-sectional associations of objectively measured physical activity with brain-derived neurotrophic factor in adolescents
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Cross-sectional associations of objectively measured physical activity with brain-derived neurotrophic factor in adolescents. / Huang, Tao; Gejl, Anne Kær; Tarp, Jakob; Andersen, Lars Bo; Peijs, Lone; Bugge, Anna.
I: Physiology & Behavior, Bind 171, 15.03.2017, s. 87-91.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Cross-sectional associations of objectively measured physical activity with brain-derived neurotrophic factor in adolescents
AU - Huang, Tao
AU - Gejl, Anne Kær
AU - Tarp, Jakob
AU - Andersen, Lars Bo
AU - Peijs, Lone
AU - Bugge, Anna
N1 - Copyright © 2016 Elsevier Inc. All rights reserved.
PY - 2017/3/15
Y1 - 2017/3/15
N2 - OBJECTIVE: The purpose of this study was to examine the associations between objectively measured physical activity and serum brain-derived neurotrophic factor (BDNF) in adolescents.METHODS: Cross-sectional analyses were performed using data from 415 adolescents who participated in the 2015 follow-up of the Childhood Health Activity and Motor Performance School Study Denmark (the CHAMPS-study DK). Physical activity was objectively measured by accelerometry monitors. Serum BDNF levels were analyzed using the Enzyme-linked immunosorbent assay (ELISA). Anthropometrics and pubertal status were measured using standardized procedures.RESULTS: With adjustment for age, pubertal status and body mass index, mean physical activity (counts per minute) was negatively associated with serum BDNF in boys (P=0.013). Similarly, moderate-to-vigorous physical activity (MVPA) was negatively associated with serum BDNF in boys (P=0.035). In girls, mean physical activity and MVPA were not associated with serum BDNF. Without adjustment for wear time, sedentary time was not associated with serum BDNF in either sex.CONCLUSION: These findings indicate that higher physical activity is associated with lower serum BDNF in boys, but not in girls.
AB - OBJECTIVE: The purpose of this study was to examine the associations between objectively measured physical activity and serum brain-derived neurotrophic factor (BDNF) in adolescents.METHODS: Cross-sectional analyses were performed using data from 415 adolescents who participated in the 2015 follow-up of the Childhood Health Activity and Motor Performance School Study Denmark (the CHAMPS-study DK). Physical activity was objectively measured by accelerometry monitors. Serum BDNF levels were analyzed using the Enzyme-linked immunosorbent assay (ELISA). Anthropometrics and pubertal status were measured using standardized procedures.RESULTS: With adjustment for age, pubertal status and body mass index, mean physical activity (counts per minute) was negatively associated with serum BDNF in boys (P=0.013). Similarly, moderate-to-vigorous physical activity (MVPA) was negatively associated with serum BDNF in boys (P=0.035). In girls, mean physical activity and MVPA were not associated with serum BDNF. Without adjustment for wear time, sedentary time was not associated with serum BDNF in either sex.CONCLUSION: These findings indicate that higher physical activity is associated with lower serum BDNF in boys, but not in girls.
KW - Accelerometry
KW - Adolescent
KW - Anthropometry
KW - Brain-Derived Neurotrophic Factor/blood
KW - Cross-Sectional Studies
KW - Enzyme-Linked Immunosorbent Assay
KW - Exercise/physiology
KW - Female
KW - Humans
KW - Male
KW - Motor Activity
KW - Sedentary Lifestyle
KW - Sexual Maturation/physiology
U2 - 10.1016/j.physbeh.2016.12.026
DO - 10.1016/j.physbeh.2016.12.026
M3 - Journal article
C2 - 28027935
VL - 171
SP - 87
EP - 91
JO - Physiology & Behavior
JF - Physiology & Behavior
SN - 0031-9384
ER -
ID: 193974811