Coupled nucleotide covariations reveal dynamic RNA interaction patterns

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Standard

Coupled nucleotide covariations reveal dynamic RNA interaction patterns. / Gultyaev, AP; Franch, T; Gerdes, K.

I: R N A, Bind 6, Nr. 11, 2000, s. 1483-1491.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Gultyaev, AP, Franch, T & Gerdes, K 2000, 'Coupled nucleotide covariations reveal dynamic RNA interaction patterns', R N A, bind 6, nr. 11, s. 1483-1491. https://doi.org/10.1017/S1355838200990708

APA

Gultyaev, AP., Franch, T., & Gerdes, K. (2000). Coupled nucleotide covariations reveal dynamic RNA interaction patterns. R N A, 6(11), 1483-1491. https://doi.org/10.1017/S1355838200990708

Vancouver

Gultyaev AP, Franch T, Gerdes K. Coupled nucleotide covariations reveal dynamic RNA interaction patterns. R N A. 2000;6(11):1483-1491. https://doi.org/10.1017/S1355838200990708

Author

Gultyaev, AP ; Franch, T ; Gerdes, K. / Coupled nucleotide covariations reveal dynamic RNA interaction patterns. I: R N A. 2000 ; Bind 6, Nr. 11. s. 1483-1491.

Bibtex

@article{7b7969793dff4957bdbd957d475e7b40,
title = "Coupled nucleotide covariations reveal dynamic RNA interaction patterns",
abstract = "Evolutionarily conserved structures in related RNA molecules contain coordinated variations (covariations) of paired nucleotides, Analysis of covariations is a very powerful approach to deduce phylogenetically conserved (i,e., functional) conformations, including tertiary interactions. Here we discuss conserved RNA folding pathways that are revealed by covariation patterns. In such pathways, structural requirements for alternative pairings cause some nucleotides to covary with two different partners. Such ``coupled'' covariations between three or more nucleotides were found in various types of RNAs, The analysis of coupled covariations can unravel important features of RNA folding dynamics and improve phylogeny reconstruction in some cases, Importantly, it is necessary to distinguish between multiple covariations determined by mutually exclusive structures and those determined by tertiary contacts.",
author = "AP Gultyaev and T Franch and K Gerdes",
year = "2000",
doi = "10.1017/S1355838200990708",
language = "English",
volume = "6",
pages = "1483--1491",
journal = "RNA",
issn = "1355-8382",
publisher = "Cold Spring Harbor Laboratory Press",
number = "11",

}

RIS

TY - JOUR

T1 - Coupled nucleotide covariations reveal dynamic RNA interaction patterns

AU - Gultyaev, AP

AU - Franch, T

AU - Gerdes, K

PY - 2000

Y1 - 2000

N2 - Evolutionarily conserved structures in related RNA molecules contain coordinated variations (covariations) of paired nucleotides, Analysis of covariations is a very powerful approach to deduce phylogenetically conserved (i,e., functional) conformations, including tertiary interactions. Here we discuss conserved RNA folding pathways that are revealed by covariation patterns. In such pathways, structural requirements for alternative pairings cause some nucleotides to covary with two different partners. Such ``coupled'' covariations between three or more nucleotides were found in various types of RNAs, The analysis of coupled covariations can unravel important features of RNA folding dynamics and improve phylogeny reconstruction in some cases, Importantly, it is necessary to distinguish between multiple covariations determined by mutually exclusive structures and those determined by tertiary contacts.

AB - Evolutionarily conserved structures in related RNA molecules contain coordinated variations (covariations) of paired nucleotides, Analysis of covariations is a very powerful approach to deduce phylogenetically conserved (i,e., functional) conformations, including tertiary interactions. Here we discuss conserved RNA folding pathways that are revealed by covariation patterns. In such pathways, structural requirements for alternative pairings cause some nucleotides to covary with two different partners. Such ``coupled'' covariations between three or more nucleotides were found in various types of RNAs, The analysis of coupled covariations can unravel important features of RNA folding dynamics and improve phylogeny reconstruction in some cases, Importantly, it is necessary to distinguish between multiple covariations determined by mutually exclusive structures and those determined by tertiary contacts.

U2 - 10.1017/S1355838200990708

DO - 10.1017/S1355838200990708

M3 - Journal article

VL - 6

SP - 1483

EP - 1491

JO - RNA

JF - RNA

SN - 1355-8382

IS - 11

ER -

ID: 97057902