Body composition at birth and height at 2 years: A prospective cohort study among children in Jimma, Ethiopia
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Body composition at birth and height at 2 years : A prospective cohort study among children in Jimma, Ethiopia. / Admassu, Bitiya; Wells, Jonathan C; Girma, Tsinuel; Andersen, Gregers Stig; Owino, Victor O; Belachew, Tefera; Michaelsen, Kim F.; Abera, Mubarek; Wibæk Christensen, Rasmus; Friis, Henrik; Kæstel, Pernille.
I: Pediatric Research, Bind 82, Nr. 2, 2017, s. 209-214.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Body composition at birth and height at 2 years
T2 - A prospective cohort study among children in Jimma, Ethiopia
AU - Admassu, Bitiya
AU - Wells, Jonathan C
AU - Girma, Tsinuel
AU - Andersen, Gregers Stig
AU - Owino, Victor O
AU - Belachew, Tefera
AU - Michaelsen, Kim F.
AU - Abera, Mubarek
AU - Wibæk Christensen, Rasmus
AU - Friis, Henrik
AU - Kæstel, Pernille
N1 - CURIS 2017 NEXS 152
PY - 2017
Y1 - 2017
N2 - Background: Low birth weight is associated with childhood stunting, but equivalent associations for birth body composition (BC) remain unknown.Objective: To assess associations of BC with height-for-age Z score (HAZ) at 2 years of age.Methods: In a prospective cohort study, fat mass (FM) and fat-free mass (FFM) were measured using air-displacement plethysmography within 48 h of birth. Linear regression models were applied to study the relationship between BC at birth and HAZ at 24 months (±3 months).Results: A total of 268 children with height assessment at 2 years were included. Mean±s.d. HAZ at 2 years of age was -1.2±1.2, with 25.8% classified as stunted (HAZ<-2 s.d.). FFM at birth was positively associated with HAZ at 2 years, independent of length at birth. When adjusted for potential confounders, HAZ at 2 years was 0.73 higher for each additional kg FFM at birth (β=0.73, 95%CI (0.08, 1.38). FM was not associated with HAZ at 2 years in any model.Conclusion: The FFM component of birth weight, independent of length, explains variability in HAZ at 2 years. Further studies are required to explore how changes in early infant BC are associated with linear growth.Pediatric Research accepted article preview online, 19 April 2017. doi:10.1038/pr.2017.59.
AB - Background: Low birth weight is associated with childhood stunting, but equivalent associations for birth body composition (BC) remain unknown.Objective: To assess associations of BC with height-for-age Z score (HAZ) at 2 years of age.Methods: In a prospective cohort study, fat mass (FM) and fat-free mass (FFM) were measured using air-displacement plethysmography within 48 h of birth. Linear regression models were applied to study the relationship between BC at birth and HAZ at 24 months (±3 months).Results: A total of 268 children with height assessment at 2 years were included. Mean±s.d. HAZ at 2 years of age was -1.2±1.2, with 25.8% classified as stunted (HAZ<-2 s.d.). FFM at birth was positively associated with HAZ at 2 years, independent of length at birth. When adjusted for potential confounders, HAZ at 2 years was 0.73 higher for each additional kg FFM at birth (β=0.73, 95%CI (0.08, 1.38). FM was not associated with HAZ at 2 years in any model.Conclusion: The FFM component of birth weight, independent of length, explains variability in HAZ at 2 years. Further studies are required to explore how changes in early infant BC are associated with linear growth.Pediatric Research accepted article preview online, 19 April 2017. doi:10.1038/pr.2017.59.
KW - Journal Article
U2 - 10.1038/pr.2017.59
DO - 10.1038/pr.2017.59
M3 - Journal article
C2 - 28422940
VL - 82
SP - 209
EP - 214
JO - Pediatric Research
JF - Pediatric Research
SN - 0031-3998
IS - 2
ER -
ID: 177084019