Influence of intranasal and carotid cooling on cerebral temperature balance and oxygenation
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Influence of intranasal and carotid cooling on cerebral temperature balance and oxygenation. / Nybo, Lars; Wanscher, Michael; Secher, Niels H.
I: Frontiers in Physiology, Bind 5, 79, 2014.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Influence of intranasal and carotid cooling on cerebral temperature balance and oxygenation
AU - Nybo, Lars
AU - Wanscher, Michael
AU - Secher, Niels H.
N1 - CURIS 2014 NEXS 057
PY - 2014
Y1 - 2014
N2 - The present study evaluated the influence of intranasal cooling with balloon catheters, increased nasal ventilation, or percutaneous cooling of the carotid arteries on cerebral temperature balance and oxygenation in six healthy male subjects. Aortic arch and internal jugular venous blood temperatures were measured to assess the cerebral heat balance and corresponding paired blood samples were obtained to evaluate cerebral metabolism and oxygenation at rest, following 60 min of intranasal cooling, 5 min of nasal ventilation, and 15 min with carotid cooling. Intranasal cooling induced a parallel drop in jugular venous and arterial blood temperatures by 0.30 ± 0.08°C (mean ± SD), whereas nasal ventilation and carotid cooling failed to lower the jugular venous blood temperature. The magnitude of the arterio-venous temperature difference across the brain remained unchanged at -0.33 ± 0.05°C following intranasal and carotid cooling, but increased to -0.44 ± 0.11°C (P
AB - The present study evaluated the influence of intranasal cooling with balloon catheters, increased nasal ventilation, or percutaneous cooling of the carotid arteries on cerebral temperature balance and oxygenation in six healthy male subjects. Aortic arch and internal jugular venous blood temperatures were measured to assess the cerebral heat balance and corresponding paired blood samples were obtained to evaluate cerebral metabolism and oxygenation at rest, following 60 min of intranasal cooling, 5 min of nasal ventilation, and 15 min with carotid cooling. Intranasal cooling induced a parallel drop in jugular venous and arterial blood temperatures by 0.30 ± 0.08°C (mean ± SD), whereas nasal ventilation and carotid cooling failed to lower the jugular venous blood temperature. The magnitude of the arterio-venous temperature difference across the brain remained unchanged at -0.33 ± 0.05°C following intranasal and carotid cooling, but increased to -0.44 ± 0.11°C (P
U2 - 10.3389/fphys.2014.00079
DO - 10.3389/fphys.2014.00079
M3 - Journal article
C2 - 24578693
VL - 5
JO - Frontiers in Physiology
JF - Frontiers in Physiology
SN - 1664-042X
M1 - 79
ER -
ID: 101826925