The effect of praziquantel against Schistosoma mansoni-infections in Botswana
Research output: Contribution to journal › Journal article › Research › peer-review
Chemotherapy of all infected individuals, using praziquantel 40 mg/kg in a single dose, was the initial component of the recently introduced control programme against Schistosoma mansoni-infections in Ngamiland, Botswana. To evaluate the effect of praziquantel in Ngamiland, 81 children were selected at random from three strata of intensities of infection. Six weeks after treatment a duplicate of Kato fecal thick smear was made. When eggs of S. mansoni were found, a new stool sample was collected and a hatching test performed. Only in case of a positive hatching test was the child considered to be infected: Cure rates between 78.6 and 90.0%, and reductions in egg output among noncured between 84.6 and 98.0% were found.
Original language | English |
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Journal | Tropical and Geographical Medicine |
Volume | 41 |
Issue number | 1 |
Pages (from-to) | 49-51 |
Number of pages | 3 |
ISSN | 0041-3232 |
Publication status | Published - Jan 1989 |
- Animals, Botswana, Child, Child, Preschool, Clinical Trials as Topic, Humans, Parasite Egg Count, Praziquantel, Random Allocation, Schistosomiasis mansoni
Research areas
ID: 72804803