The August Krogh Section for Molecular Physiology

The August Krogh Section for Molecular Physiology conducts research aimed at developing in-depth knowledge regarding metabolic regulation in relation to physical activity, nutrition, and health.

Research

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

The August Krogh Section for Molecular Physiology uses advanced molecular biological methods in combination with genetically modified animals and special human populations to conduct ground breaking research that spans from man to molecule.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Research is carried out from ‘molecule to man’, and uses molecular biological techniques, genetically modified animals and healthy and health-compromised people in the research. The vision is that observations based on experiments conducted in people can be explained at the molecular level, and similarly that mechanistic basic research in the laboratory can lead to new findings, that can be transferred to the human organism and the population.

For example, the section investigates:

  • Molecular mechanisms that regulate carbohydrate and fat metabolism during exercise.
  • Regulation of insulin sensitivity after physical activity and inactivity (and the role of diet in this context).
  • Interplay between physical activity and diet on performance and health parameters.
  • How physical activity combined with different diets affects metabolism, insulin sensitivity, and gene expression in men and women.

 

 

Selected publications from the section

Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function. Blazev R, Carl CS, Ng YK, Molendijk J, Voldstedlund CT, Zhao Y, Xiao D, Kueh AJ, Miotto PM, Haynes VR, Hardee JP, Chung JD, McNamara JW, Qian H, Gregorevic P, Oakhill JS, Herold MJ, Jensen TE, Lisowski L, Lynch GS, Dodd GT, Watt MJ, Yang P, Kiens B, Richter EA, Parker BL. Cell Metab. 2022 Oct 4;34(10):1561-1577.e9. Epub 2022 Jul 25.

Personalized phosphoproteomics identifies functional signaling. Needham EJ, Hingst JR, Parker BL, Morrison KR, Yang G, Onslev J, Kristensen JM, Højlund K, Ling NXY, Oakhill JS, Richter EA, Kiens B, Petersen J, Pehmøller C, James DE, Wojtaszewski JFP, Humphrey SJ. Nat Biotechnol. 2022 Apr;40(4):576-584. Epub 2021 Dec 2.

TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction. Rasmus Kjøbsted; Jonas M. Kristensen; Nicolas O. Eskesen; Kohei Kido; Klara Fjorder; Ditte F. Damgaard; Jeppe K. Larsen; Nicoline R. Andersen; Jesper B. Birk; Anders Gudiksen; Jonas T. Treebak; Peter Schjerling; Henriette Pilegaard; Jørgen F. P. Wojtaszewski. Diabetes.

Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle. Jonas R Knudsen Is a corresponding author, Kaspar W Persson, Carlos Henriquez-Olguin, Zhencheng Li, Nicolas Di Leo, Sofie A Hesselager, Steffen H Raun, Janne R Hingst, Raphaël Trouillon, Martin Wohlwend, Jørgen FP Wojtaszewski, Martin AM Gijs, Thomas Elbenhardt Jensen. Elife.

AXIN1 knockout does not alter AMPK/mTORC1 regulation and glucose metabolism in mouse skeletal muscle
Li, J.Knudsen, Jonas RolandHenriquez Olguín, CarlosLi, Z.Birk, Jesper BratzPersson, K. W.Hellsten, YlvaOffergeld, A.Jarassier, W.Grand, F. L.Schjerling, P.Wojtaszewski, Jørgen F P & Jensen, Thomas Elbenhardt2021I: Journal of Physiology. 59912s. 3081-3100 20 s.

See all the publications from the section.

 

 

Head of section: Professor Jørgen Wojtaszewski

Section Research Coordinator: Kate Wickham

Visiting address
The August Krogh Section for Molecular Physiology
Department of Nutrition, Exercise and Sports
Universitetsparken 13
DK 2100 Copenhagen
Denmark

Postal address
Department of Nutrition, Exercise and Sports
The August Krogh Section for Molecular Physiology
Nørre Allé 51
DK 2200 Copenhagen N
Denmark

See overview map of North Campus

Content not available due to cookie preferences

You cannot see the content of this field because of your cookie preferences.

Click here to change your cookie settings.

Category: Marketing

Plan your trip
Link til Rejseplanen

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Section members

Name Title Phone E-mail
Search in Name Search in Title Search in Phone
Amalie London PhD Student   E-mail
Annemarie Lundsgaard Assistant Professor +4535321755 E-mail
Aslak Emil Lyster PhD Fellow +4535333692 E-mail
Bente Kiens Professor +4535321619 E-mail
Betina Bolmgren Biomedical Laboratory Scientist +4535321748 E-mail
Carlos Henriquez Olguín Postdoc   E-mail
Casper Møller Sigvardsen Research Assistant +4535324780 E-mail
Christian Strini Carl Postdoc   E-mail
Christian Thomas Voldstedlund PhD Fellow +4535325095
Elise Needham Guest Researcher   E-mail
Erik A. Richter Professor +4535321626 E-mail
Farina Leonie Schlabs Visiting Student   E-mail
Irene Bech Nielsen Biomedical Laboratory Scientist +4535321752 E-mail
Jakob Krøll Jensen Research Assistant   E-mail
Jesper Bratz Birk Academic Staff +4535321613 E-mail
Johan Dejgaard Onslev Postdoc   E-mail
Jonas Roland Knudsen Postdoc   E-mail
Josephine Maria Kanta PhD Fellow   E-mail
Jørgen Wojtaszewski Professor, Head of Section +4535321625 E-mail
Kaspar Wredstrøm Persson PhD Fellow +4535320305 E-mail
Liljana Diskovska Cleaning Assistant +4535321574 E-mail
Louise Slot Christiansen Postdoc +4535324818 E-mail
Lykke Sylow Visiting Associate Professor +4535321767 E-mail
Magnus Romme Leandersson PhD Fellow +4535320766 E-mail
Maximilian Kleinert Assistant Professor +4535321769 E-mail
Nicki Winfield Almquist Postdoc +4535336083 E-mail
Nicolai Stevns Henriksen Academic Research Staff +4535325071 E-mail
Nicolas Oldenburg Eskesen Postdoc +4535333826 E-mail
Nicoline Resen Andersen Academic Staff +4535321765 E-mail
Nicoline Vilhelmine Vestergaard Guest Researcher   E-mail
Nikolaj Winther Research Assistant +4535326604 E-mail
Rasmus Kjøbsted Assistant Professor +4535321764 E-mail
Roberto Andrés Meneses Valdés PhD Student   E-mail
Samantha Alicia Gallero San Martín Research Assistant   E-mail
Thomas Elbenhardt Jensen Associate Professor +4535321757 E-mail
Trine Sand Nicolaisen Research Assistant   E-mail

Content not available due to cookie preferences

You cannot see the content of this field because of your cookie preferences.

Click here to change your cookie settings.

Category: Marketing