TY - JOUR

T1 - Low-calorie sweeteners in the human diet: Scientific evidence, recommendations, challenges and future needs.

T2 - A symposium report from the FENS 2019 conference

AU - Gallagher, Alison M

AU - Ashwell, Margaret

AU - Halford, Jason C G

AU - Hardman, Charlotte A

AU - Maloney, Niamh G

AU - Raben, Anne

N1 - CURIS 2021 NEXS 061

PY - 2021

Y1 - 2021

N2 - Overconsumption of free sugars, particularly from sugar-sweetened beverages (SSB), has potential negative health impacts. Implementation of a range of public health strategies is needed to reduce intakes of free sugars, including reducing portion sizes, promoting healthier dietary choices and reformulating foods and beverages. Although low-calorie sweeteners (LCS) are a useful tool for reducing energy intake and control glucose response when consuming sweet foods and drinks, several opinions persist about the adverse health effects of LCS, many of which are based on poor, little or no scientific evidence. This symposium report summarises key messages of the presentations and related discussions delivered at a scientific symposium at the 13th European Nutrition Conference (FENS 2019). These presentations considered the scientific evidence and current recommendations about the use and potential benefits of LCS for human health, with a particular focus on current evidence in relation to body weight and glycaemic control. Many of the studies to date on LCS have focused on low-calorie sweetened beverages (LCSB); however, the psychological and behavioural factors influencing consumer beliefs and consumption of LCSB need to be further explored. Current recommendations for LCS use are described, including the conclusions from a recent expert consensus report identifying the challenges that remain with LCS research. Finally, existing knowledge gaps and future actions are described, as well as two large ongoing research projects: SWITCH and SWEET.

AB - Overconsumption of free sugars, particularly from sugar-sweetened beverages (SSB), has potential negative health impacts. Implementation of a range of public health strategies is needed to reduce intakes of free sugars, including reducing portion sizes, promoting healthier dietary choices and reformulating foods and beverages. Although low-calorie sweeteners (LCS) are a useful tool for reducing energy intake and control glucose response when consuming sweet foods and drinks, several opinions persist about the adverse health effects of LCS, many of which are based on poor, little or no scientific evidence. This symposium report summarises key messages of the presentations and related discussions delivered at a scientific symposium at the 13th European Nutrition Conference (FENS 2019). These presentations considered the scientific evidence and current recommendations about the use and potential benefits of LCS for human health, with a particular focus on current evidence in relation to body weight and glycaemic control. Many of the studies to date on LCS have focused on low-calorie sweetened beverages (LCSB); however, the psychological and behavioural factors influencing consumer beliefs and consumption of LCSB need to be further explored. Current recommendations for LCS use are described, including the conclusions from a recent expert consensus report identifying the challenges that remain with LCS research. Finally, existing knowledge gaps and future actions are described, as well as two large ongoing research projects: SWITCH and SWEET.

KW - Glycaemic control

KW - Intense sweeteners

KW - Low-energy sweeteners

KW - Non-nutritive sweeteners

KW - Nutrition policy

KW - Weight management

UR - http://www.scopus.com/inward/record.url?scp=85100025641&partnerID=8YFLogxK

U2 - 10.1017/jns.2020.59

DO - 10.1017/jns.2020.59

M3 - Review

C2 - 33889390

AN - SCOPUS:85100025641

VL - 10

JO - Journal of Nutritional Science

JF - Journal of Nutritional Science

SN - 2048-6790

M1 - e7

ER -