BCG protects against tuberculosis irrespective of HIV status: a matched case-control study in Mwanza, Tanzania
Research output: Contribution to journal › Letter › Research › peer-review
While BCG vaccine protects against severe tuberculosis (TB) in children, its effect against adult TB is questionable. Furthermore, it is not known if HIV co-infection modifies the effect of BCG. Among 352 pairs of Tanzanian TB cases and matched controls, the BCG scar was associated with a reduced risk of TB (OR 0.3, 95% CI 0.2 to 0.7, p=0.005), irrespective of HIV status (interaction, p=0.623). BCG vaccination considerably reduced the risk of TB, both among individuals with and without HIV infection.
Original language | English |
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Journal | Thorax |
Volume | 68 |
Issue number | 3 |
Pages (from-to) | 288-289 |
Number of pages | 2 |
ISSN | 0040-6376 |
DOIs | |
Publication status | Published - 2013 |
ID: 44566701