A novel treatment for weight reduction by the recombinant "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin"

Research output: Contribution to journal › Review › Research › peer-review

Standard

A novel treatment for weight reduction by the recombinant "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin". / Jalili, Mahsa; Bazi, Zahra; Hekmatdoost, Azita.

In: Journal of Integrative Medicine, Vol. 14, No. 1, 2016, p. 1-4.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Jalili, M, Bazi, Z & Hekmatdoost, A 2016, 'A novel treatment for weight reduction by the recombinant "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin"', Journal of Integrative Medicine, vol. 14, no. 1, pp. 1-4. https://doi.org/10.1016/S2095-4964(16)60242-X

APA

Jalili, M., Bazi, Z., & Hekmatdoost, A. (2016). A novel treatment for weight reduction by the recombinant "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin". Journal of Integrative Medicine, 14(1), 1-4. https://doi.org/10.1016/S2095-4964(16)60242-X

Vancouver

Jalili M, Bazi Z, Hekmatdoost A. A novel treatment for weight reduction by the recombinant "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin". Journal of Integrative Medicine. 2016;14(1):1-4. https://doi.org/10.1016/S2095-4964(16)60242-X

Author

Jalili, Mahsa ; Bazi, Zahra ; Hekmatdoost, Azita. / A novel treatment for weight reduction by the recombinant "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin". In: Journal of Integrative Medicine. 2016 ; Vol. 14, No. 1. pp. 1-4.

Bibtex

@article{95fa1d11dae243cb9b36335b02c1a5e5,
title = "A novel treatment for weight reduction by the recombinant {"}Pichia pastoris{"} yeast expressing the hybrid protein of {"}irisin-furin-transferrin{"}",
abstract = "Obesity is a major health problem across the world, but there are few ways to effectively treat or manage it in the long term. Researchers are searching for more convenient, cost-effective and noninvasive therapies for overweight and obese people. Recent studies have illustrated that the microbiome of the body's different organs can be used as a vehicle for in-situ gene therapy. We suggest that the recombinant form of {"}Pichia pastoris{"} yeast expressing the hybrid protein of {"}irisin-furin-transferrin{"} under the control of the enolase 1 promoter is a new nutraceutical strategy to absorb fewer calories from intestinal nutrients, and induce a higher metabolic rate to expend more calories, similar to that from engaging in physical activity. By comparison, this method can be a long-term, noninvasive treatment and can be used for obese patients who have movement limitations.",
keywords = "Biotechnology, DNA, recombinant, Nutrition, Obesity",
author = "Mahsa Jalili and Zahra Bazi and Azita Hekmatdoost",
note = "(Ekstern)",
year = "2016",
doi = "10.1016/S2095-4964(16)60242-X",
language = "English",
volume = "14",
pages = "1--4",
journal = "Journal of integrative medicine",
issn = "2095-4964",
publisher = "Kexue Chubanshe",
number = "1",

}

RIS

TY - JOUR

T1 - A novel treatment for weight reduction by the recombinant "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin"

AU - Jalili, Mahsa

AU - Bazi, Zahra

AU - Hekmatdoost, Azita

N1 - (Ekstern)

PY - 2016

Y1 - 2016

N2 - Obesity is a major health problem across the world, but there are few ways to effectively treat or manage it in the long term. Researchers are searching for more convenient, cost-effective and noninvasive therapies for overweight and obese people. Recent studies have illustrated that the microbiome of the body's different organs can be used as a vehicle for in-situ gene therapy. We suggest that the recombinant form of "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin" under the control of the enolase 1 promoter is a new nutraceutical strategy to absorb fewer calories from intestinal nutrients, and induce a higher metabolic rate to expend more calories, similar to that from engaging in physical activity. By comparison, this method can be a long-term, noninvasive treatment and can be used for obese patients who have movement limitations.

AB - Obesity is a major health problem across the world, but there are few ways to effectively treat or manage it in the long term. Researchers are searching for more convenient, cost-effective and noninvasive therapies for overweight and obese people. Recent studies have illustrated that the microbiome of the body's different organs can be used as a vehicle for in-situ gene therapy. We suggest that the recombinant form of "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin" under the control of the enolase 1 promoter is a new nutraceutical strategy to absorb fewer calories from intestinal nutrients, and induce a higher metabolic rate to expend more calories, similar to that from engaging in physical activity. By comparison, this method can be a long-term, noninvasive treatment and can be used for obese patients who have movement limitations.

KW - Biotechnology

KW - DNA, recombinant

KW - Nutrition

KW - Obesity

UR - http://www.scopus.com/inward/record.url?scp=85057497264&partnerID=8YFLogxK

U2 - 10.1016/S2095-4964(16)60242-X

DO - 10.1016/S2095-4964(16)60242-X

M3 - Review

C2 - 26778222

AN - SCOPUS:85057497264

VL - 14

SP - 1

EP - 4

JO - Journal of integrative medicine

JF - Journal of integrative medicine

SN - 2095-4964

IS - 1

ER -

ID: 248338664