What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply

Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › fagfællebedømt

Standard

What really matters with thrombocytopenia : absolute value, timing, etiology or management? Author's reply. / Anthon, Carl Thomas; Pène, Frédéric; Chawla, Sanjay; Puxty, Kathryn; Russell, Lene.

I: Intensive Care Medicine, Bind 50, Nr. 2, 2024, s. 306-307.

Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › fagfællebedømt

Harvard

Anthon, CT, Pène, F, Chawla, S, Puxty, K & Russell, L 2024, 'What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply', Intensive Care Medicine, bind 50, nr. 2, s. 306-307. https://doi.org/10.1007/s00134-023-07312-4

APA

Anthon, C. T., Pène, F., Chawla, S., Puxty, K., & Russell, L. (2024). What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply. Intensive Care Medicine, 50(2), 306-307. https://doi.org/10.1007/s00134-023-07312-4

Vancouver

Anthon CT, Pène F, Chawla S, Puxty K, Russell L. What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply. Intensive Care Medicine. 2024;50(2):306-307. https://doi.org/10.1007/s00134-023-07312-4

Author

Anthon, Carl Thomas ; Pène, Frédéric ; Chawla, Sanjay ; Puxty, Kathryn ; Russell, Lene. / What really matters with thrombocytopenia : absolute value, timing, etiology or management? Author's reply. I: Intensive Care Medicine. 2024 ; Bind 50, Nr. 2. s. 306-307.

Bibtex

@article{11e1af5b467c47e58b75a01da655a7b2,
title = "What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply",
abstract = "Thrombocytopenia in the intensive care unit (ICU) is a complex condition with diverse contributing factors often concurrently present. While associated with worse outcomes [2, 3], the extent to which underlying cause(s), disease severity, or thrombocytopenia itself impacts prognosis is uncertain and likely varies between subpopulations. Although we agree that the aetiology, mechanisms and subsequent management of thrombocytopenia are important, this was not the focus of the PLOT-ICU study, and we did not collect data on presumed or confirmed causes of thrombocytopenia besides underlying comorbid conditions. This would have required a different setup, including a systematic and comprehensive diagnostic workup of patients with thrombocytopenia and a considerably larger sample size.",
author = "Anthon, {Carl Thomas} and Fr{\'e}d{\'e}ric P{\`e}ne and Sanjay Chawla and Kathryn Puxty and Lene Russell",
note = "Funding Information: The Department of Intensive Care at Rigshospitalet (CTA) has received funding for other projects from the Novo Nordisk Foundation, Sygeforsikringen {\textquoteleft}danmark{\textquoteright}, and Pfizer and has conducted contract research for AM‑Pharma. FP has received honoraria for consulting and lectures from Gilead and an institutional grant from Alexion Pharma. SC, KP and LR have no conflict of interest to declare. ",
year = "2024",
doi = "10.1007/s00134-023-07312-4",
language = "English",
volume = "50",
pages = "306--307",
journal = "European Journal of Intensive Care Medicine",
issn = "0935-1701",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - What really matters with thrombocytopenia

T2 - absolute value, timing, etiology or management? Author's reply

AU - Anthon, Carl Thomas

AU - Pène, Frédéric

AU - Chawla, Sanjay

AU - Puxty, Kathryn

AU - Russell, Lene

N1 - Funding Information: The Department of Intensive Care at Rigshospitalet (CTA) has received funding for other projects from the Novo Nordisk Foundation, Sygeforsikringen ‘danmark’, and Pfizer and has conducted contract research for AM‑Pharma. FP has received honoraria for consulting and lectures from Gilead and an institutional grant from Alexion Pharma. SC, KP and LR have no conflict of interest to declare.

PY - 2024

Y1 - 2024

N2 - Thrombocytopenia in the intensive care unit (ICU) is a complex condition with diverse contributing factors often concurrently present. While associated with worse outcomes [2, 3], the extent to which underlying cause(s), disease severity, or thrombocytopenia itself impacts prognosis is uncertain and likely varies between subpopulations. Although we agree that the aetiology, mechanisms and subsequent management of thrombocytopenia are important, this was not the focus of the PLOT-ICU study, and we did not collect data on presumed or confirmed causes of thrombocytopenia besides underlying comorbid conditions. This would have required a different setup, including a systematic and comprehensive diagnostic workup of patients with thrombocytopenia and a considerably larger sample size.

AB - Thrombocytopenia in the intensive care unit (ICU) is a complex condition with diverse contributing factors often concurrently present. While associated with worse outcomes [2, 3], the extent to which underlying cause(s), disease severity, or thrombocytopenia itself impacts prognosis is uncertain and likely varies between subpopulations. Although we agree that the aetiology, mechanisms and subsequent management of thrombocytopenia are important, this was not the focus of the PLOT-ICU study, and we did not collect data on presumed or confirmed causes of thrombocytopenia besides underlying comorbid conditions. This would have required a different setup, including a systematic and comprehensive diagnostic workup of patients with thrombocytopenia and a considerably larger sample size.

U2 - 10.1007/s00134-023-07312-4

DO - 10.1007/s00134-023-07312-4

M3 - Comment/debate

C2 - 38189931

AN - SCOPUS:85181711633

VL - 50

SP - 306

EP - 307

JO - European Journal of Intensive Care Medicine

JF - European Journal of Intensive Care Medicine

SN - 0935-1701

IS - 2

ER -

ID: 379707130