Understanding risk and causal mechanisms for developing obesity in infants and young children: A National Institutes of Health workshop
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Understanding risk and causal mechanisms for developing obesity in infants and young children : A National Institutes of Health workshop. / Aagaard, Kjersti M.; Barkin, Shari L.; Burant, Charles F.; Carnell, Susan; Demerath, Ellen; Donovan, Sharon M.; Eneli, Ihuoma; Francis, Lori A.; Gilbert-Diamond, Diane; Hivert, Marie France; LeBourgeois, Monique K.; Loos, Ruth J.F.; Lumeng, Julie C.; Miller, Alison L.; Okely, Anthony D.; Osganian, Stavroula K.; Ramirez, Amelie G.; Trasande, Leonardo; Van Horn, Linda V.; Wake, Melissa; Wright, Rosalind J.; Yanovski, Susan Z.
I: Obesity Reviews, Bind 25, Nr. 4, e13690, 2024.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Understanding risk and causal mechanisms for developing obesity in infants and young children
T2 - A National Institutes of Health workshop
AU - Aagaard, Kjersti M.
AU - Barkin, Shari L.
AU - Burant, Charles F.
AU - Carnell, Susan
AU - Demerath, Ellen
AU - Donovan, Sharon M.
AU - Eneli, Ihuoma
AU - Francis, Lori A.
AU - Gilbert-Diamond, Diane
AU - Hivert, Marie France
AU - LeBourgeois, Monique K.
AU - Loos, Ruth J.F.
AU - Lumeng, Julie C.
AU - Miller, Alison L.
AU - Okely, Anthony D.
AU - Osganian, Stavroula K.
AU - Ramirez, Amelie G.
AU - Trasande, Leonardo
AU - Van Horn, Linda V.
AU - Wake, Melissa
AU - Wright, Rosalind J.
AU - Yanovski, Susan Z.
N1 - Publisher Copyright: © 2024 World Obesity Federation.
PY - 2024
Y1 - 2024
N2 - Obesity in children remains a major public health problem, with the current prevalence in youth ages 2–19 years estimated to be 19.7%. Despite progress in identifying risk factors, current models do not accurately predict development of obesity in early childhood. There is also substantial individual variability in response to a given intervention that is not well understood. On April 29–30, 2021, the National Institutes of Health convened a virtual workshop on “Understanding Risk and Causal Mechanisms for Developing Obesity in Infants and Young Children.” The workshop brought together scientists from diverse disciplines to discuss (1) what is known regarding epidemiology and underlying biological and behavioral mechanisms for rapid weight gain and development of obesity and (2) what new approaches can improve risk prediction and gain novel insights into causes of obesity in early life. Participants identified gaps and opportunities for future research to advance understanding of risk and underlying mechanisms for development of obesity in early life. It was emphasized that future studies will require multi-disciplinary efforts across basic, behavioral, and clinical sciences. An exposome framework is needed to elucidate how behavioral, biological, and environmental risk factors interact. Use of novel statistical methods may provide greater insights into causal mechanisms.
AB - Obesity in children remains a major public health problem, with the current prevalence in youth ages 2–19 years estimated to be 19.7%. Despite progress in identifying risk factors, current models do not accurately predict development of obesity in early childhood. There is also substantial individual variability in response to a given intervention that is not well understood. On April 29–30, 2021, the National Institutes of Health convened a virtual workshop on “Understanding Risk and Causal Mechanisms for Developing Obesity in Infants and Young Children.” The workshop brought together scientists from diverse disciplines to discuss (1) what is known regarding epidemiology and underlying biological and behavioral mechanisms for rapid weight gain and development of obesity and (2) what new approaches can improve risk prediction and gain novel insights into causes of obesity in early life. Participants identified gaps and opportunities for future research to advance understanding of risk and underlying mechanisms for development of obesity in early life. It was emphasized that future studies will require multi-disciplinary efforts across basic, behavioral, and clinical sciences. An exposome framework is needed to elucidate how behavioral, biological, and environmental risk factors interact. Use of novel statistical methods may provide greater insights into causal mechanisms.
KW - childhood obesity
KW - childhood obesity prevention
KW - childhood obesity risk
U2 - 10.1111/obr.13690
DO - 10.1111/obr.13690
M3 - Review
C2 - 38204366
AN - SCOPUS:85181941209
VL - 25
JO - Obesity Reviews
JF - Obesity Reviews
SN - 1467-7881
IS - 4
M1 - e13690
ER -
ID: 379640009