Seminal fluid excretion of cytomegalovirus related to immunosuppression in homosexual men
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Seminal fluid samples from 84 Danish homosexual men were successfully cultured to determine the prevalence of cytomegalovirus excretion. Ten (15%) out of 66 men positive for the antibody were found to be excreting the virus. Although the proportion excreting was inversely related to age (p <0.01), three men aged over 30 and with many years of homosexual experience excreted the virus. In addition, a 50 year old man with Kaposi's sarcoma excreted the virus. A further study of the ratio of T cell helpers to suppressors in the men aged over 30 and a series of age matched non-excreting homosexual control or heterosexual men showed that those excreting cytomegalovirus in their seminal fluid had statistically lower ratios (all <0.77) than the controls (p <0.05). Excretion of cytomegalovirus may be related to re-emergence of latent infection in immunosuppressed homosexual men.
Originalsprog | Engelsk |
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Tidsskrift | BMJ Innovations |
Vol/bind | 286 |
Udgave nummer | 6383 |
Sider (fra-til) | 2010-2012 |
Antal sider | 3 |
ISSN | 2055-8074 |
DOI | |
Status | Udgivet - 1983 |
ID: 260895025