Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography

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Standard

Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography. / Lassen, N A; Henriksen, L; Paulson, O.

I: Stroke, Bind 12, Nr. 3, 01.05.1981, s. 284-8.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Lassen, NA, Henriksen, L & Paulson, O 1981, 'Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography', Stroke, bind 12, nr. 3, s. 284-8. https://doi.org/10.1161/01.str.12.3.284

APA

Lassen, N. A., Henriksen, L., & Paulson, O. (1981). Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography. Stroke, 12(3), 284-8. https://doi.org/10.1161/01.str.12.3.284

Vancouver

Lassen NA, Henriksen L, Paulson O. Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography. Stroke. 1981 maj 1;12(3):284-8. https://doi.org/10.1161/01.str.12.3.284

Author

Lassen, N A ; Henriksen, L ; Paulson, O. / Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography. I: Stroke. 1981 ; Bind 12, Nr. 3. s. 284-8.

Bibtex

@article{af529a05aaf14b88b8e53dcf5774444f,
title = "Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography",
abstract = "A rapidly rotating single-photon emission tomograph was used to study regional cerebral blood flow by 133Xenon inhalation. Using a rotation speed of 180 degrees/5 sec a tomographic picture of the average Xenon concentration in 3 slices is obtained. By taking a sequence of 4 one-minute tomograms during and after a one-minute 133Xenon inhalation period a flow-dependent variation in local isotope concentration is seen. This sequence is used for calculating CBF by a deconvolution procedure. The CBF maps have a spatial resolution of approximately 1.7 cm (FWHM). This preliminary study comprises normal subjects and 10 unselected patients with stroke. The CBF tomograms localized appropriate ischemic areas in all 10 patients. In one patient the conventional x-ray tomogram was negative, while the flow tomogram clearly showed a decreased flow in consonance with the clinical findings. Regional cerebral blood flow measured tomographically by 133Xenon inhalation circumvents the extra-cranial contamination and the superposition of intracranial tissues that hamper 133Xenon inhalation flow studies using stationary detectors.",
keywords = "Adult, Aged, Brain Ischemia/diagnostic imaging, Cerebrovascular Circulation, Cerebrovascular Disorders, Female, Humans, Male, Middle Aged, Radiography, Tomography, Emission-Computed, Xenon",
author = "Lassen, {N A} and L Henriksen and O Paulson",
year = "1981",
month = may,
day = "1",
doi = "10.1161/01.str.12.3.284",
language = "English",
volume = "12",
pages = "284--8",
journal = "Stroke",
issn = "0039-2499",
publisher = "Lippincott Williams & Wilkins",
number = "3",

}

RIS

TY - JOUR

T1 - Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography

AU - Lassen, N A

AU - Henriksen, L

AU - Paulson, O

PY - 1981/5/1

Y1 - 1981/5/1

N2 - A rapidly rotating single-photon emission tomograph was used to study regional cerebral blood flow by 133Xenon inhalation. Using a rotation speed of 180 degrees/5 sec a tomographic picture of the average Xenon concentration in 3 slices is obtained. By taking a sequence of 4 one-minute tomograms during and after a one-minute 133Xenon inhalation period a flow-dependent variation in local isotope concentration is seen. This sequence is used for calculating CBF by a deconvolution procedure. The CBF maps have a spatial resolution of approximately 1.7 cm (FWHM). This preliminary study comprises normal subjects and 10 unselected patients with stroke. The CBF tomograms localized appropriate ischemic areas in all 10 patients. In one patient the conventional x-ray tomogram was negative, while the flow tomogram clearly showed a decreased flow in consonance with the clinical findings. Regional cerebral blood flow measured tomographically by 133Xenon inhalation circumvents the extra-cranial contamination and the superposition of intracranial tissues that hamper 133Xenon inhalation flow studies using stationary detectors.

AB - A rapidly rotating single-photon emission tomograph was used to study regional cerebral blood flow by 133Xenon inhalation. Using a rotation speed of 180 degrees/5 sec a tomographic picture of the average Xenon concentration in 3 slices is obtained. By taking a sequence of 4 one-minute tomograms during and after a one-minute 133Xenon inhalation period a flow-dependent variation in local isotope concentration is seen. This sequence is used for calculating CBF by a deconvolution procedure. The CBF maps have a spatial resolution of approximately 1.7 cm (FWHM). This preliminary study comprises normal subjects and 10 unselected patients with stroke. The CBF tomograms localized appropriate ischemic areas in all 10 patients. In one patient the conventional x-ray tomogram was negative, while the flow tomogram clearly showed a decreased flow in consonance with the clinical findings. Regional cerebral blood flow measured tomographically by 133Xenon inhalation circumvents the extra-cranial contamination and the superposition of intracranial tissues that hamper 133Xenon inhalation flow studies using stationary detectors.

KW - Adult

KW - Aged

KW - Brain Ischemia/diagnostic imaging

KW - Cerebrovascular Circulation

KW - Cerebrovascular Disorders

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Radiography

KW - Tomography, Emission-Computed

KW - Xenon

U2 - 10.1161/01.str.12.3.284

DO - 10.1161/01.str.12.3.284

M3 - Journal article

C2 - 6972635

VL - 12

SP - 284

EP - 288

JO - Stroke

JF - Stroke

SN - 0039-2499

IS - 3

ER -

ID: 279596109