TY - JOUR

T1 - Regional cerebral blood flow by radioxenon-113 inhalation and dynamic emission tomography

AU - Lassen, N A

AU - Henriksen, L

AU - Paulson, O B

PY - 1981

Y1 - 1981

N2 - A rapidly rotating single photon tomograph is described for atraumatic and three-dimensional measurements of rCBF in ml/100 g/min. The instrument has a high sensitivity permitting the recording of the uptake and washout of xenon-133 from the human brain during and after inhalation of the gas at a concentration of 10 mCi/l for 1 min. The algorithm used to calculate rCBF is described, and clinical results in particular in stroke cases are presented. The rapidly rotating tomograph is better suited for the study of focal cerebral ischemia than the conventional stationary detectors because superposition of tissue layers is avoided.

AB - A rapidly rotating single photon tomograph is described for atraumatic and three-dimensional measurements of rCBF in ml/100 g/min. The instrument has a high sensitivity permitting the recording of the uptake and washout of xenon-133 from the human brain during and after inhalation of the gas at a concentration of 10 mCi/l for 1 min. The algorithm used to calculate rCBF is described, and clinical results in particular in stroke cases are presented. The rapidly rotating tomograph is better suited for the study of focal cerebral ischemia than the conventional stationary detectors because superposition of tissue layers is avoided.

KW - Brain Ischemia/diagnostic imaging

KW - Brain Neoplasms/diagnostic imaging

KW - Cerebral Infarction/diagnostic imaging

KW - Cerebrovascular Circulation

KW - Humans

KW - Tomography, Emission-Computed/methods

KW - Visual Perception/physiology

KW - Xenon Radioisotopes

M3 - Journal article

C2 - 6976590

VL - 7

SP - 110

EP - 117

JO - Progress in nuclear medicine

JF - Progress in nuclear medicine

SN - 0091-7559

ER -