Endophthalmitis following same-day bilateral anti-VEGF injections: a systematic review
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Endophthalmitis following same-day bilateral anti-VEGF injections : a systematic review. / Bjerager, Jakob; Hajari, Javad; Klefter, Oliver Niels; Subhi, Yousif; Schneider, Miklos.
I: International Ophthalmology, Bind 44, Nr. 1, 2024, s. 37.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Endophthalmitis following same-day bilateral anti-VEGF injections
T2 - a systematic review
AU - Bjerager, Jakob
AU - Hajari, Javad
AU - Klefter, Oliver Niels
AU - Subhi, Yousif
AU - Schneider, Miklos
N1 - Publisher Copyright: © 2024. The Author(s), under exclusive licence to Springer Nature B.V.
PY - 2024
Y1 - 2024
N2 - PURPOSE: To review the risk of endophthalmitis in same-day bilateral anti-VEGF injections. METHODS: We searched 12 literature databases for studies on the risk of endophthalmitis after same-day bilateral intravitreal anti-VEGF injections. Data extraction was made independently by two authors and discussed afterward until reaching consensus. RESULTS: Seventeen studies were included with a total of 138,478 intravitreal anti-VEGF injections (69,239 bilateral injections sessions) given in at least 7579 patients. In total, 33 cases of endophthalmitis had occurred, and no cases were bilateral. The incidence of endophthalmitis ranged from 0 to 0.53% per intravitreal injection across studies. CONCLUSIONS: We suggest that clinicians can consider same-day treatment of both eyes of patients in need of bilateral intravitreal anti-VEGF injection therapy, but larger studies are needed to quantify the exact risk of endophthalmitis.
AB - PURPOSE: To review the risk of endophthalmitis in same-day bilateral anti-VEGF injections. METHODS: We searched 12 literature databases for studies on the risk of endophthalmitis after same-day bilateral intravitreal anti-VEGF injections. Data extraction was made independently by two authors and discussed afterward until reaching consensus. RESULTS: Seventeen studies were included with a total of 138,478 intravitreal anti-VEGF injections (69,239 bilateral injections sessions) given in at least 7579 patients. In total, 33 cases of endophthalmitis had occurred, and no cases were bilateral. The incidence of endophthalmitis ranged from 0 to 0.53% per intravitreal injection across studies. CONCLUSIONS: We suggest that clinicians can consider same-day treatment of both eyes of patients in need of bilateral intravitreal anti-VEGF injection therapy, but larger studies are needed to quantify the exact risk of endophthalmitis.
KW - Adverse event
KW - Anti-VEGF
KW - Bilateral
KW - Endophthalmitis
KW - Injection
KW - Intravitreal
KW - Risk
KW - Same-day
KW - Same-session
KW - Systematic review
U2 - 10.1007/s10792-024-02983-4
DO - 10.1007/s10792-024-02983-4
M3 - Review
C2 - 38332399
AN - SCOPUS:85184791009
VL - 44
SP - 37
JO - International Ophthalmology
JF - International Ophthalmology
SN - 0165-5701
IS - 1
ER -
ID: 383705291