Standard
Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections. / Bergsten, Helena; Madsen, Martin Bruun; Bergey, Francois; Hyldegaard, Ole; Skrede, Steinar; Arnell, Per; Oppegaard, Oddvar; Itzek, Andreas; Perner, Anders; Svensson, Mattias; Norrby-Teglund, Anna; INFECT Study Group.
I:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Bind 71, Nr. 7, 2020, s. 1772-1775.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Bergsten, H, Madsen, MB, Bergey, F
, Hyldegaard, O, Skrede, S, Arnell, P, Oppegaard, O, Itzek, A
, Perner, A, Svensson, M, Norrby-Teglund, A & INFECT Study Group 2020, '
Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections',
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, bind 71, nr. 7, s. 1772-1775.
https://doi.org/10.1093/cid/ciaa022APA
Bergsten, H., Madsen, M. B., Bergey, F.
, Hyldegaard, O., Skrede, S., Arnell, P., Oppegaard, O., Itzek, A.
, Perner, A., Svensson, M., Norrby-Teglund, A., & INFECT Study Group (2020).
Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America,
71(7), 1772-1775.
https://doi.org/10.1093/cid/ciaa022Vancouver
Bergsten H, Madsen MB, Bergey F
, Hyldegaard O, Skrede S, Arnell P o.a.
Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2020;71(7):1772-1775.
https://doi.org/10.1093/cid/ciaa022Author
Bergsten, Helena ; Madsen, Martin Bruun ; Bergey, Francois ; Hyldegaard, Ole ; Skrede, Steinar ; Arnell, Per ; Oppegaard, Oddvar ; Itzek, Andreas ; Perner, Anders ; Svensson, Mattias ; Norrby-Teglund, Anna ; INFECT Study Group. / Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections. I: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2020 ; Bind 71, Nr. 7. s. 1772-1775.
Bibtex
@article{1c3683be3aa94a32abb282db4c8a3eaf,
title = "Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections",
abstract = "Analyses of plasma collected pre- and postadministration of intravenous immunoglobulin (IVIG) from patients with group A Streptococcus necrotizing soft tissue infections demonstrated a negative correlation between IVIG dose and toxin-triggered T-cell proliferation (r = -.67, P < .0001). One 25-g IVIG dose was sufficient to yield plasma-neutralizing activity against streptococcal superantigens. Clinical Trials Registration. NCT01790698 and NCT02111161.",
keywords = "Streptococcus pyogenes, intravenous immunoglobulin G, necrotizing fasciitis, necrotizing soft tissue infections, superantigens",
author = "Helena Bergsten and Madsen, {Martin Bruun} and Francois Bergey and Ole Hyldegaard and Steinar Skrede and Per Arnell and Oddvar Oppegaard and Andreas Itzek and Anders Perner and Mattias Svensson and Anna Norrby-Teglund and {INFECT Study Group}",
year = "2020",
doi = "10.1093/cid/ciaa022",
language = "English",
volume = "71",
pages = "1772--1775",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "7",
}
RIS
TY - JOUR
T1 - Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections
AU - Bergsten, Helena
AU - Madsen, Martin Bruun
AU - Bergey, Francois
AU - Hyldegaard, Ole
AU - Skrede, Steinar
AU - Arnell, Per
AU - Oppegaard, Oddvar
AU - Itzek, Andreas
AU - Perner, Anders
AU - Svensson, Mattias
AU - Norrby-Teglund, Anna
AU - INFECT Study Group
PY - 2020
Y1 - 2020
N2 - Analyses of plasma collected pre- and postadministration of intravenous immunoglobulin (IVIG) from patients with group A Streptococcus necrotizing soft tissue infections demonstrated a negative correlation between IVIG dose and toxin-triggered T-cell proliferation (r = -.67, P < .0001). One 25-g IVIG dose was sufficient to yield plasma-neutralizing activity against streptococcal superantigens. Clinical Trials Registration. NCT01790698 and NCT02111161.
AB - Analyses of plasma collected pre- and postadministration of intravenous immunoglobulin (IVIG) from patients with group A Streptococcus necrotizing soft tissue infections demonstrated a negative correlation between IVIG dose and toxin-triggered T-cell proliferation (r = -.67, P < .0001). One 25-g IVIG dose was sufficient to yield plasma-neutralizing activity against streptococcal superantigens. Clinical Trials Registration. NCT01790698 and NCT02111161.
KW - Streptococcus pyogenes
KW - intravenous immunoglobulin G
KW - necrotizing fasciitis
KW - necrotizing soft tissue infections
KW - superantigens
U2 - 10.1093/cid/ciaa022
DO - 10.1093/cid/ciaa022
M3 - Journal article
C2 - 31916575
AN - SCOPUS:85094683894
VL - 71
SP - 1772
EP - 1775
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
SN - 1058-4838
IS - 7
ER -
