c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

  • Karly C Sourris
  • Jasmine G Lyons
  • Maximilian de Courten
  • Sonia L Dougherty
  • Darren C Henstridge
  • Mark E Cooper
  • Michelle Hage
  • Anthony Dart
  • Bronwyn A Kingwell
  • Josephine M Forbes
  • Barbora de Courten
Chronic low-grade activation of the immune system (CLAIS) predicts type 2 diabetes via a decrease in insulin sensitivity. Our study investigated potential relationships between nuclear factor-kappaB (NF-kappaB) and c-Jun NH(2)-terminal kinase (JNK) pathways-two pathways proposed as the link between CLAIS and insulin resistance.
OriginalsprogEngelsk
TidsskriftDiabetes
Vol/bind58
Udgave nummer6
Sider (fra-til)1259-65
Antal sider7
ISSN0012-1797
DOI
StatusUdgivet - 1 jun. 2009

ID: 33899737