Cerebral blood flow following normovolemic hemodilution in patients with high hematocrit

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Standard

Cerebral blood flow following normovolemic hemodilution in patients with high hematocrit. / Henriksen, L; Paulson, O B; Smith, R J.

I: Annals of Neurology, Bind 9, Nr. 5, 05.1981, s. 454-7.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Henriksen, L, Paulson, OB & Smith, RJ 1981, 'Cerebral blood flow following normovolemic hemodilution in patients with high hematocrit', Annals of Neurology, bind 9, nr. 5, s. 454-7. https://doi.org/10.1002/ana.410090507

APA

Henriksen, L., Paulson, O. B., & Smith, R. J. (1981). Cerebral blood flow following normovolemic hemodilution in patients with high hematocrit. Annals of Neurology, 9(5), 454-7. https://doi.org/10.1002/ana.410090507

Vancouver

Henriksen L, Paulson OB, Smith RJ. Cerebral blood flow following normovolemic hemodilution in patients with high hematocrit. Annals of Neurology. 1981 maj;9(5):454-7. https://doi.org/10.1002/ana.410090507

Author

Henriksen, L ; Paulson, O B ; Smith, R J. / Cerebral blood flow following normovolemic hemodilution in patients with high hematocrit. I: Annals of Neurology. 1981 ; Bind 9, Nr. 5. s. 454-7.

Bibtex

@article{5861022d097a4504b84440e2d830e1b9,
title = "Cerebral blood flow following normovolemic hemodilution in patients with high hematocrit",
abstract = "The effects on cerebral hemodynamics of venisection and a 4% albumin-saline infusion were studied in six patients with high hematocrit (mean, 51.5%). Cerebral blood flow (CBF) was measured using the xenon 133 intracarotid injection method. Blood gases were measured in arterial and jugular venous blood. Rapid two-stage hemodilution, which lowered mean hematocrit by 9 and 13%, resulted in CBF increases of 19 and 23%, respectively. Jugular venous partial pressure of oxygen and oxygen delivery capacity (CBF x arterial oxygen content) did not change significantly from baseline. The cerebral metabolic rate for oxygen increased slightly following stage 1 hemodilution but returned to baseline value following stage 2. The study lends no support to the concept that patients whose hematocrit is at the high end of the normal range have generalized cerebral hypoxia.",
keywords = "Adult, Aged, Bloodletting, Cerebrovascular Disorders/etiology, Female, Hematocrit, Hematologic Diseases/complications, Hemodilution, Homeostasis, Humans, Hypoxia, Brain/etiology, Male, Middle Aged",
author = "L Henriksen and Paulson, {O B} and Smith, {R J}",
year = "1981",
month = may,
doi = "10.1002/ana.410090507",
language = "English",
volume = "9",
pages = "454--7",
journal = "Annals of Neurology",
issn = "0364-5134",
publisher = "JohnWiley & Sons, Inc.",
number = "5",

}

RIS

TY - JOUR

T1 - Cerebral blood flow following normovolemic hemodilution in patients with high hematocrit

AU - Henriksen, L

AU - Paulson, O B

AU - Smith, R J

PY - 1981/5

Y1 - 1981/5

N2 - The effects on cerebral hemodynamics of venisection and a 4% albumin-saline infusion were studied in six patients with high hematocrit (mean, 51.5%). Cerebral blood flow (CBF) was measured using the xenon 133 intracarotid injection method. Blood gases were measured in arterial and jugular venous blood. Rapid two-stage hemodilution, which lowered mean hematocrit by 9 and 13%, resulted in CBF increases of 19 and 23%, respectively. Jugular venous partial pressure of oxygen and oxygen delivery capacity (CBF x arterial oxygen content) did not change significantly from baseline. The cerebral metabolic rate for oxygen increased slightly following stage 1 hemodilution but returned to baseline value following stage 2. The study lends no support to the concept that patients whose hematocrit is at the high end of the normal range have generalized cerebral hypoxia.

AB - The effects on cerebral hemodynamics of venisection and a 4% albumin-saline infusion were studied in six patients with high hematocrit (mean, 51.5%). Cerebral blood flow (CBF) was measured using the xenon 133 intracarotid injection method. Blood gases were measured in arterial and jugular venous blood. Rapid two-stage hemodilution, which lowered mean hematocrit by 9 and 13%, resulted in CBF increases of 19 and 23%, respectively. Jugular venous partial pressure of oxygen and oxygen delivery capacity (CBF x arterial oxygen content) did not change significantly from baseline. The cerebral metabolic rate for oxygen increased slightly following stage 1 hemodilution but returned to baseline value following stage 2. The study lends no support to the concept that patients whose hematocrit is at the high end of the normal range have generalized cerebral hypoxia.

KW - Adult

KW - Aged

KW - Bloodletting

KW - Cerebrovascular Disorders/etiology

KW - Female

KW - Hematocrit

KW - Hematologic Diseases/complications

KW - Hemodilution

KW - Homeostasis

KW - Humans

KW - Hypoxia, Brain/etiology

KW - Male

KW - Middle Aged

U2 - 10.1002/ana.410090507

DO - 10.1002/ana.410090507

M3 - Journal article

C2 - 7271240

VL - 9

SP - 454

EP - 457

JO - Annals of Neurology

JF - Annals of Neurology

SN - 0364-5134

IS - 5

ER -

ID: 279693417