Laboratory facilities
We provide untargeted metabolomics analysis on most biological matrices as our main expertise.
These include urine, blood plasma/serum, fecal extracts, tissue extracts and cell or media extracts. We work mainly with human samples or samples from experimental or domestic animals; but we can also profile cultured cells or the growth media.
We also do a series of targeted quantitative and semi-quantitative analysis of compounds relevant for a wide range of applications in nutritional research, currently including:
Quantitative
- Bile Acids (fecal)
- Alcohol intake biomarkers (Urine, blood, hair)
- Carotenoids (serum)
- Microbial metabolites (e.g. indole derivatives, phenols in urine)
- Short straight- and branched-chain fatty acids, C1-C6 (fecal),
Semiquantitative
Phenols/phenolic acids; 3,4-dihydroxy phenylpropionic acid, 3,4-dihydroxycinnamic acid, 3-hydroxy phenylpropionic acid, 4-methoxy-3-hydroxycinnamic acid, 4-hydroxy phenylacetic acid, 4-hydroxy-3-methoxy phenylpropionic acid, and 4-hydroxycinnamic acid (fecal)
Fatty Acids; linoleic acid, oleic acid, palmitoleic acid, docosahexaenoic acid (plasma/serum)
For details, logistics and prices, this depends on the collaborative agreement, which may include several arrangements including various kinds of research collaboration with co-publication or full commercial analytical services, please inquire metabolomicslab@nexs.ku.dk.
Mass spectrometry detectors
- UHPLC H-Class + Qtof Premier (Waters, Milfold, MA, USA)
- UHPLC H-Class + Vion (Waters, Milfold, MA, USA)
- UHPLC H-Class + TQD (Waters, Milfold, MA, USA)
- UHPLC Classic + Synapt G2 (Waters, Milfold, MA, USA)
Other detectors
- UHPLC Classic + photodiode array detector (Waters, Milfold, MA, USA)
- UHPLC + fraction collector (Waters, Milfold, MA, USA)