Effect of protein intake and physical activity on 24-h pattern and rate of macronutrient utilization
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Effect of protein intake and physical activity on 24-h pattern and rate of macronutrient utilization. / Forslund, Anders; El-Khoury, Antoine E; Olsson, Roger M; Sjödin, Anders Mikael; Hambraeus, Leif; Young, Vernon R.
I: American Journal of Physiology - Endocrinology and Metabolism, Bind 276, Nr. 5, 1999, s. E964-E976.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Effect of protein intake and physical activity on 24-h pattern and rate of macronutrient utilization
AU - Forslund, Anders
AU - El-Khoury, Antoine E
AU - Olsson, Roger M
AU - Sjödin, Anders Mikael
AU - Hambraeus, Leif
AU - Young, Vernon R
PY - 1999
Y1 - 1999
N2 - Effects of moderate physical activity (90 min at 45-50% of maximal O2 uptake 2 times daily) and 'high, (2.5 g protein · kg-1 · day-1, n = 6) or 'normal' protein intake (1.0 g protein · kg-1 · day-1, n = 8) on the pattern and rate of 24-h macronutrient utilization in healthy adult men were compared after a diet-exercise-adjustment period of 6 days. Energy turnover (ET) was determined by indirect and direct (suit) calorimetry, and 'protein oxidation' was determined by a 24-h continuous intravenous infusion of [1- 13C]leucine. Subjects were in slight positive energy balance during both studies. Protein contributed to a higher (22 vs. 10%) and carbohydrate (CHO) a lower (33 vs. 58%) proportion of total 24-h ET on the high- vs. normal- protein intake. The highest contribution of fat to ET was seen postexercise during fasting (73 and 61% of ET for high and normal, respectively). With the high-protein diet the subjects were in a positive protein (P < 0.001) and CHO balance (P < 0.05) and a negative fat balance (P < 0.05). The increased ET postexercise was not explained by increased rates of urea production and/or protein synthesis.
AB - Effects of moderate physical activity (90 min at 45-50% of maximal O2 uptake 2 times daily) and 'high, (2.5 g protein · kg-1 · day-1, n = 6) or 'normal' protein intake (1.0 g protein · kg-1 · day-1, n = 8) on the pattern and rate of 24-h macronutrient utilization in healthy adult men were compared after a diet-exercise-adjustment period of 6 days. Energy turnover (ET) was determined by indirect and direct (suit) calorimetry, and 'protein oxidation' was determined by a 24-h continuous intravenous infusion of [1- 13C]leucine. Subjects were in slight positive energy balance during both studies. Protein contributed to a higher (22 vs. 10%) and carbohydrate (CHO) a lower (33 vs. 58%) proportion of total 24-h ET on the high- vs. normal- protein intake. The highest contribution of fat to ET was seen postexercise during fasting (73 and 61% of ET for high and normal, respectively). With the high-protein diet the subjects were in a positive protein (P < 0.001) and CHO balance (P < 0.05) and a negative fat balance (P < 0.05). The increased ET postexercise was not explained by increased rates of urea production and/or protein synthesis.
KW - Carbohydrate
KW - Direct calorimetry
KW - Energy turnover
KW - Fat
KW - Indirect calorimetry
KW - Macronutrient utilization
KW - Obesity
KW - Physical exercise
KW - Protein
KW - Stable isotopes
UR - http://www.scopus.com/inward/record.url?scp=0033045543&partnerID=8YFLogxK
U2 - 10.1152/ajpendo.1999.276.5.E964
DO - 10.1152/ajpendo.1999.276.5.E964
M3 - Journal article
C2 - 10329992
AN - SCOPUS:0033045543
VL - 276
SP - E964-E976
JO - A J P: Endocrinology and Metabolism (Online)
JF - A J P: Endocrinology and Metabolism (Online)
SN - 1522-1555
IS - 5
ER -
ID: 211153103