n-3 PUFA status in school children is associated with beneficial lipid profile, reduced physical activity and increased blood pressure in boys
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Dietary n-3 long-chain PUFA (LC-PUFA) improve dyslipidaemia and hypertension and may affect insulin resistance and adiposity. Increasing numbers of children show signs of the metabolic syndrome (MetS), but few studies have investigated the association with n-3 LC-PUFA status. We examined the relationship between fasting whole-blood EPA or DHA (w/w% of the total fatty acids, FA%) and markers of the MetS (anthropometry, blood pressure, plasma lipids and glucose homeostasis) cross-sectionally in seventy-three 8-11-year-old Danish children from the OPUS School Meal Pilot Study (OPUS is an acronym of the project 'Optimal well-being, development and health for Danish children through a healthy New Nordic Diet' and is supported by a grant from the Nordea Foundation). Also, we explored the potential mediating effects of physical activity and energy intake. Girls had higher body fat percentage (BF%), diastolic blood pressure, heart rate, plasma TAG, insulin, homeostasis model assessment-insulin resistance and glycosylated Hb than boys. Sexes did not differ in fish or macronutrient intake or whole-blood fatty acids. After adjustment for sex, age and total whole-blood fatty acid concentration, BF% and HDL:TAG increased with whole-blood EPA (ß>0·25, P
Originalsprog | Engelsk |
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Tidsskrift | British Journal of Nutrition |
Vol/bind | 110 |
Udgave nummer | 7 |
Sider (fra-til) | 1304-1312 |
Antal sider | 9 |
ISSN | 0007-1145 |
DOI | |
Status | Udgivet - 2013 |
Bibliografisk note
CURIS 2013 NEXS 079
ID: 45250000