Daily energy expenditure through the human life course
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Daily energy expenditure through the human life course. / Pontzer, Herman; Yamada, Yosuke; Sagayama, Hiroyuki; Sjödin, Anders Mikael; IAEA DLW Database Consortium.
I: Science, Bind 373, Nr. 6556, 2021, s. 808-812.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Daily energy expenditure through the human life course
AU - Pontzer, Herman
AU - Yamada, Yosuke
AU - Sagayama, Hiroyuki
AU - Ainslie, Philip N
AU - Andersen, Lene F
AU - Anderson, Liam J
AU - Arab, Lenore
AU - Baddou, Issaad
AU - Bedu-Addo, Kweku
AU - Blaak, Ellen E
AU - Blanc, Stephane
AU - Bonomi, Alberto G
AU - Bouten, Carlijn V C
AU - Bovet, Pascal
AU - Buchowski, Maciej S
AU - Butte, Nancy F
AU - Camps, Stefan G
AU - Close, Graeme L
AU - Cooper, Jamie A
AU - Cooper, Richard
AU - Das, Sai Krupa
AU - Dugas, Lara R
AU - Ekelund, Ulf
AU - Entringer, Sonja
AU - Forrester, Terrence
AU - Fudge, Barry W
AU - Goris, Annelies H
AU - Gurven, Michael
AU - Hambly, Catherine
AU - El Hamdouchi, Asmaa
AU - Hoos, Marjije B
AU - Hu, Sumei
AU - Joonas, Noorjehan
AU - Joosen, Annemiek M
AU - Katzmarzyk, Peter
AU - Kempen, Kitty P
AU - Kimura, Misaka
AU - Kraus, William E
AU - Kushner, Robert F
AU - Lambert, Estelle V
AU - Leonard, William R
AU - Lessan, Nader
AU - Martin, Corby
AU - Medin, Anine C
AU - Meijer, Erwin P
AU - Morehen, James C
AU - Morton, James P
AU - Neuhouser, Marian L
AU - Sjödin, Anders Mikael
AU - Wood, Brian M
AU - IAEA DLW Database Consortium
N1 - Publisher Copyright: Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works
PY - 2021
Y1 - 2021
N2 - Total daily energy expenditure (“total expenditure”) reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, diverse database of total expenditure measured by the doubly labeled water method for males and females aged 8 days to 95 years. Total expenditure increased with fat-free mass in a power-law manner, with four distinct life stages. Fat-free mass-adjusted expenditure accelerates rapidly in neonates to ~50% above adult values at ~1 year; declines slowly to adult levels by ~20 years; remains stable in adulthood (20 to 60 years), even during pregnancy; then declines in older adults. These changes shed light on human development and aging and should help shape nutrition and health strategies across the life span.
AB - Total daily energy expenditure (“total expenditure”) reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, diverse database of total expenditure measured by the doubly labeled water method for males and females aged 8 days to 95 years. Total expenditure increased with fat-free mass in a power-law manner, with four distinct life stages. Fat-free mass-adjusted expenditure accelerates rapidly in neonates to ~50% above adult values at ~1 year; declines slowly to adult levels by ~20 years; remains stable in adulthood (20 to 60 years), even during pregnancy; then declines in older adults. These changes shed light on human development and aging and should help shape nutrition and health strategies across the life span.
U2 - 10.1126/science.abe5017
DO - 10.1126/science.abe5017
M3 - Journal article
C2 - 34385400
AN - SCOPUS:85112515247
VL - 373
SP - 808
EP - 812
JO - Science
JF - Science
SN - 0036-8075
IS - 6556
ER -
ID: 276848061