Transforming growth factor-β activation in cell-free extracellular matrix preparations: Commentary
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Dokumenter
- 66341-195919-2-PB
Forlagets udgivne version, 78,6 KB, PDF-dokument
Transforming growth factor-β (TGF-β) is an important regulator of many cellular and immunological functions. It is often deposited in extracellular matrices in a latent form. This commentary is to draw attention to the likelihood that preparing cell-free matrices from tissue cultures by high pH buffers, such as ammonium hydroxide, can activate the TGF-β. Therefore, cells subsequently seeded onto such matrices may respond to the presence of active TGF-β in addition to interactions with macromolecular extracellular matrix components.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Folia Histochemica et Cytobiologica |
Vol/bind | 57 |
Udgave nummer | 4 |
Sider (fra-til) | 157-158 |
ISSN | 0239-8508 |
DOI | |
Status | Udgivet - 2019 |
- Det Sundhedsvidenskabelige Fakultet
Forskningsområder
Antal downloads er baseret på statistik fra Google Scholar og www.ku.dk
Ingen data tilgængelig
ID: 231600560