High bone mineral apparent density in children with X-linked hypophosphatemia
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High bone mineral apparent density in children with X-linked hypophosphatemia. / Beck-Nielsen, Signe; Brixen, K; Gram, J; Mølgaard, Christian.
I: Osteoporosis International, Bind 24, Nr. 8, 2013, s. 2215-2221.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - High bone mineral apparent density in children with X-linked hypophosphatemia
AU - Beck-Nielsen, Signe
AU - Brixen, K
AU - Gram, J
AU - Mølgaard, Christian
N1 - CURIS 2013 NEXS 146
PY - 2013
Y1 - 2013
N2 - Bone mineral apparent density (BMAD) in children with X-linked hypophosphatemia (XLH) was evaluated, as they are unlikely to have extra-skeletal ossifications contributing to the elevated bone mineral density of the spine in adult patients. Children with XLH also had significantly higher BMAD of the spine compared to femoral neck. INTRODUCTION: BMAD obtained by dual-energy X-ray absorptiometry scans in children with XLH was evaluated, as they are unlikely to have the extra-skeletal ossifications contributing to the elevated bone mineral density of the spine in adult patients. METHODS: A total of 15 children with biochemically and genetically verified XLH were recruited. Anthropometric measurements were performed, and to correct for the short stature (small bones), the BMAD of the spine and the femoral neck was evaluated. RESULTS: Z-scores of BMAD of the spine (mean (95 % CI); 2.0 (1.3-2.7); p
AB - Bone mineral apparent density (BMAD) in children with X-linked hypophosphatemia (XLH) was evaluated, as they are unlikely to have extra-skeletal ossifications contributing to the elevated bone mineral density of the spine in adult patients. Children with XLH also had significantly higher BMAD of the spine compared to femoral neck. INTRODUCTION: BMAD obtained by dual-energy X-ray absorptiometry scans in children with XLH was evaluated, as they are unlikely to have the extra-skeletal ossifications contributing to the elevated bone mineral density of the spine in adult patients. METHODS: A total of 15 children with biochemically and genetically verified XLH were recruited. Anthropometric measurements were performed, and to correct for the short stature (small bones), the BMAD of the spine and the femoral neck was evaluated. RESULTS: Z-scores of BMAD of the spine (mean (95 % CI); 2.0 (1.3-2.7); p
U2 - 10.1007/s00198-013-2286-9
DO - 10.1007/s00198-013-2286-9
M3 - Journal article
C2 - 23389694
VL - 24
SP - 2215
EP - 2221
JO - Osteoporosis International
JF - Osteoporosis International
SN - 0937-941X
IS - 8
ER -
ID: 46982280