The August Krogh Section for Human Physiology

The August Krogh Section for Human Physiology conducts cutting-edge research in the areas of basal human and exercise physiology with a focus on cardiovascular and skeletal muscle physiology in the context of health and disease as well as exercise.

Research groups

 

Our vision is to be at the forefront of cutting-edge research in human physiology through the utilization of invasive human experiments and novel methodologies to understand the mechanisms underpinning human health and disease.

 

 

 

 

 

 

Our research program utilizes a top-down approach to develop a mechanistic understanding of cardiovascular and skeletal muscle physiology in the context of health and disease as well as exercise.

For example, the section investigates:

  • Impact of exercise training and/or pharmacological interventions on cardiovascular and muscle health (healthy, aging, disease populations)
  • Optimization of performance in elite athletes through various ergogenic manipulations (training modalities, supplements)
  • Female-specific cardiovascular and skeletal muscle physiology in response to exercise training and/or pharmacological interventions (menstrual cycle, oral contraceptives, menopause)

 

 

Selected publications from the section

High-intensity interval training remodels the proteome and acetylome of human skeletal muscle. Hostrup M, Lemminger AK, Stocks B, Gonzalez-Franquesa A, Larsen JK, Quesada JP, Thomassen M, Weinert BT, Bangsbo J, Deshmukh AS. Elife. 2022 May 31;11:e69802.

Is the Pannexin-1 Channel a Mechanism Underlying Hypertension in Humans? a Translational Study of Human Hypertension. Gliemann L, Tamariz-Ellemann A, Collin Hansen C, Svare Ehlers T, Møller S, Hellsten Y. Hypertension. 2022 May;79(5):1132-1143. Epub 2022 Mar 16.

Changes in Immature Reticulocytes Aid the Indirect Detection of Micro-Dose Recombinant Erythropoietin use in Males and Females. Breenfeldt Andersen A, Bejder J, Bonne TC, Graae J, Seier S, Nordsborg NB. Med Sci Sports Exerc. 2023 Apr 25. Online ahead of print.

Redox balance in human skeletal muscle-derived endothelial cells - Effect of exercise training. Hansen C, Møller S, Ehlers T, Wickham KA, Bangsbo J, Gliemann L, Hellsten Y. Free Radic Biol Med. 2022 Feb 1;179:144-155. Epub 2021 Dec 22.

Muscle Ionic Shifts During Exercise: Implications for Fatigue and Exercise Performance. Hostrup M, Cairns SP, Bangsbo J. Compr Physiol. 2021 Jun 30;11(3):1895-1959.

See all the publications from the section.

 

 

Head of section: Professor Ylva Hellsten

Section Research Coordinator: Kate Wickham

Visiting address
The August Krogh Section for Human Physiology
Department of Nutrition, Exercise and Sports
Universitetsparken 13
DK 2100 Copenhagen
Denmark

Postal address
Department of Nutrition, Exercise and Sports
The August Krogh Section for Human Physiology
Nørre Allé 51
DK 2200 Copenhagen N
Denmark

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Public transport
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Members of research group

Name Title Phone E-mail
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Ylva Hellsten

Head of Section

Ylva Hellsten
Professor

LEAF - Laboratory Efficiency Assessment Framework

The laboratory has been awarded the LEAF - Laboratory Efficiency Assessment Framework Bronze certificate.