Role of epinephrine for muscular glycogenolysis and pancreatic hormonal secretion in running rats

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Standard

Role of epinephrine for muscular glycogenolysis and pancreatic hormonal secretion in running rats. / Richter, Erik A.; Sonne, B; Christensen, N J; Galbo, H.

I: American Journal of Physiology (Consolidated), Bind 240, Nr. 5, 1981, s. E526-E532.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Richter, EA, Sonne, B, Christensen, NJ & Galbo, H 1981, 'Role of epinephrine for muscular glycogenolysis and pancreatic hormonal secretion in running rats', American Journal of Physiology (Consolidated), bind 240, nr. 5, s. E526-E532.

APA

Richter, E. A., Sonne, B., Christensen, N. J., & Galbo, H. (1981). Role of epinephrine for muscular glycogenolysis and pancreatic hormonal secretion in running rats. American Journal of Physiology (Consolidated), 240(5), E526-E532.

Vancouver

Richter EA, Sonne B, Christensen NJ, Galbo H. Role of epinephrine for muscular glycogenolysis and pancreatic hormonal secretion in running rats. American Journal of Physiology (Consolidated). 1981;240(5):E526-E532.

Author

Richter, Erik A. ; Sonne, B ; Christensen, N J ; Galbo, H. / Role of epinephrine for muscular glycogenolysis and pancreatic hormonal secretion in running rats. I: American Journal of Physiology (Consolidated). 1981 ; Bind 240, Nr. 5. s. E526-E532.

Bibtex

@article{b8e0e061f6144a6a9d472d1ae17278fb,
title = "Role of epinephrine for muscular glycogenolysis and pancreatic hormonal secretion in running rats",
abstract = "We have previously shown that during swimming muscular glycogen breakdown was diminished and plasma glucagon and insulin were lower and higher, respectively, in adrenodemedullated rats compared to controls. These findings might be due to a lower work intensity or higher efficiency in adrenodemedullated rats than in controls. Furthermore, they might be due to either an acute or a chronic influence of epinephrine. Rats were adrenodemedullated (DM) or sham-operated (C). They were chronically cannulated and either rested or ran in a metabolism chamber for 45 min. Running DM rats had either saline (DM-S) or epinephrine (normalizing the concentration in plasma) (DM-E) infused. During running, oxygen uptake was identical in C and DM rats. Muscular glycogen breakdown was similar in DM-E and C rats and higher than in DM-S rats. Blood glucose, lactate, and heart rate increased in C and DM-E, but not in DM-S rats. In spite of the differences in blood glucose, plasma insulin was the same in all groups and plasma glucagon increased identically in all running rats. Plasma FFA and liver glycogen were similar in all groups. In conclusion. in running rats, epinephrine exerts an acute enhancing effect on muscular glycogenolysis, glucagon secretion, and heart rate and an acute depressing effect on insulin secretion.",
keywords = "Adrenal Medulla, Animals, Blood Glucose, Epinephrine, Glucagon, Glycogen, Insulin, Male, Muscles, Physical Exertion, Rats",
author = "Richter, {Erik A.} and B Sonne and Christensen, {N J} and H Galbo",
year = "1981",
language = "English",
volume = "240",
pages = "E526--E532",
journal = "American Journal of Physiology (Consolidated)",
issn = "0002-9513",
publisher = "American Physiological Society",
number = "5",

}

RIS

TY - JOUR

T1 - Role of epinephrine for muscular glycogenolysis and pancreatic hormonal secretion in running rats

AU - Richter, Erik A.

AU - Sonne, B

AU - Christensen, N J

AU - Galbo, H

PY - 1981

Y1 - 1981

N2 - We have previously shown that during swimming muscular glycogen breakdown was diminished and plasma glucagon and insulin were lower and higher, respectively, in adrenodemedullated rats compared to controls. These findings might be due to a lower work intensity or higher efficiency in adrenodemedullated rats than in controls. Furthermore, they might be due to either an acute or a chronic influence of epinephrine. Rats were adrenodemedullated (DM) or sham-operated (C). They were chronically cannulated and either rested or ran in a metabolism chamber for 45 min. Running DM rats had either saline (DM-S) or epinephrine (normalizing the concentration in plasma) (DM-E) infused. During running, oxygen uptake was identical in C and DM rats. Muscular glycogen breakdown was similar in DM-E and C rats and higher than in DM-S rats. Blood glucose, lactate, and heart rate increased in C and DM-E, but not in DM-S rats. In spite of the differences in blood glucose, plasma insulin was the same in all groups and plasma glucagon increased identically in all running rats. Plasma FFA and liver glycogen were similar in all groups. In conclusion. in running rats, epinephrine exerts an acute enhancing effect on muscular glycogenolysis, glucagon secretion, and heart rate and an acute depressing effect on insulin secretion.

AB - We have previously shown that during swimming muscular glycogen breakdown was diminished and plasma glucagon and insulin were lower and higher, respectively, in adrenodemedullated rats compared to controls. These findings might be due to a lower work intensity or higher efficiency in adrenodemedullated rats than in controls. Furthermore, they might be due to either an acute or a chronic influence of epinephrine. Rats were adrenodemedullated (DM) or sham-operated (C). They were chronically cannulated and either rested or ran in a metabolism chamber for 45 min. Running DM rats had either saline (DM-S) or epinephrine (normalizing the concentration in plasma) (DM-E) infused. During running, oxygen uptake was identical in C and DM rats. Muscular glycogen breakdown was similar in DM-E and C rats and higher than in DM-S rats. Blood glucose, lactate, and heart rate increased in C and DM-E, but not in DM-S rats. In spite of the differences in blood glucose, plasma insulin was the same in all groups and plasma glucagon increased identically in all running rats. Plasma FFA and liver glycogen were similar in all groups. In conclusion. in running rats, epinephrine exerts an acute enhancing effect on muscular glycogenolysis, glucagon secretion, and heart rate and an acute depressing effect on insulin secretion.

KW - Adrenal Medulla

KW - Animals

KW - Blood Glucose

KW - Epinephrine

KW - Glucagon

KW - Glycogen

KW - Insulin

KW - Male

KW - Muscles

KW - Physical Exertion

KW - Rats

M3 - Journal article

C2 - 7015878

VL - 240

SP - E526-E532

JO - American Journal of Physiology (Consolidated)

JF - American Journal of Physiology (Consolidated)

SN - 0002-9513

IS - 5

ER -

ID: 154760375