Fertilizer type affects stable isotope ratios of nitrogen in human blood plasma - results from two-year controlled agricultural field trials and a randomized crossover dietary intervention study

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Standard

Fertilizer type affects stable isotope ratios of nitrogen in human blood plasma - results from two-year controlled agricultural field trials and a randomized crossover dietary intervention study. / Mie, Axel; Novák, Vlastimil; Franko, Mikael Andersson; Bügel, Susanne Gjedsted; Laursen, Kristian Holst.

I: Journal of Agricultural and Food Chemistry, Bind 70, Nr. 11, 2022, s. 3391-3399.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Mie, A, Novák, V, Franko, MA, Bügel, SG & Laursen, KH 2022, 'Fertilizer type affects stable isotope ratios of nitrogen in human blood plasma - results from two-year controlled agricultural field trials and a randomized crossover dietary intervention study', Journal of Agricultural and Food Chemistry, bind 70, nr. 11, s. 3391-3399. https://doi.org/10.1021/acs.jafc.1c04418

APA

Mie, A., Novák, V., Franko, M. A., Bügel, S. G., & Laursen, K. H. (2022). Fertilizer type affects stable isotope ratios of nitrogen in human blood plasma - results from two-year controlled agricultural field trials and a randomized crossover dietary intervention study. Journal of Agricultural and Food Chemistry, 70(11), 3391-3399. https://doi.org/10.1021/acs.jafc.1c04418

Vancouver

Mie A, Novák V, Franko MA, Bügel SG, Laursen KH. Fertilizer type affects stable isotope ratios of nitrogen in human blood plasma - results from two-year controlled agricultural field trials and a randomized crossover dietary intervention study. Journal of Agricultural and Food Chemistry. 2022;70(11):3391-3399. https://doi.org/10.1021/acs.jafc.1c04418

Author

Mie, Axel ; Novák, Vlastimil ; Franko, Mikael Andersson ; Bügel, Susanne Gjedsted ; Laursen, Kristian Holst. / Fertilizer type affects stable isotope ratios of nitrogen in human blood plasma - results from two-year controlled agricultural field trials and a randomized crossover dietary intervention study. I: Journal of Agricultural and Food Chemistry. 2022 ; Bind 70, Nr. 11. s. 3391-3399.

Bibtex

@article{1ffcb2d2e30c4dbea1d89f3dfa75bb40,
title = "Fertilizer type affects stable isotope ratios of nitrogen in human blood plasma - results from two-year controlled agricultural field trials and a randomized crossover dietary intervention study",
abstract = "The stable nitrogen isotope ratio δ15N is used as a marker of dietary protein sources in blood. Crop fertilization strategies affect δ15N in plant foods. In a double-blinded randomized cross-over dietary intervention trial with 33 participants, we quantified the effect of fertilizer type (conventional: synthetic fertilizer and organic: animal or green manure) on δ15N in blood plasma. At study baseline, plasma δ15N was +9.34 ± 0.29‰ (mean ± standard deviation). After 12 days intervention with a diet based on crops fertilized with animal manure, plasma δ15N was shifted by +0.27 ± 0.04‰ (mean ± standard error) compared to synthetic fertilization and by +0.22 ± 0.04‰ compared to fertilization with green manure (both p < 0.0001). Accordingly, differences in the δ15N values between fertilizers are propagated to the blood plasma of human consumers. The results indicate a need to consider agricultural practices when using δ15N as a dietary biomarker.",
keywords = "Faculty of Science, Dietary protein, Fertilizer type, Organic food, Production systems, Stable nitrogen isotopes",
author = "Axel Mie and Vlastimil Nov{\'a}k and Franko, {Mikael Andersson} and B{\"u}gel, {Susanne Gjedsted} and Laursen, {Kristian Holst}",
note = "CURIS 2022 NEXS 079",
year = "2022",
doi = "10.1021/acs.jafc.1c04418",
language = "English",
volume = "70",
pages = "3391--3399",
journal = "Journal of Agricultural and Food Chemistry",
issn = "0021-8561",
publisher = "American Chemical Society",
number = "11",

}

RIS

TY - JOUR

T1 - Fertilizer type affects stable isotope ratios of nitrogen in human blood plasma - results from two-year controlled agricultural field trials and a randomized crossover dietary intervention study

AU - Mie, Axel

AU - Novák, Vlastimil

AU - Franko, Mikael Andersson

AU - Bügel, Susanne Gjedsted

AU - Laursen, Kristian Holst

N1 - CURIS 2022 NEXS 079

PY - 2022

Y1 - 2022

N2 - The stable nitrogen isotope ratio δ15N is used as a marker of dietary protein sources in blood. Crop fertilization strategies affect δ15N in plant foods. In a double-blinded randomized cross-over dietary intervention trial with 33 participants, we quantified the effect of fertilizer type (conventional: synthetic fertilizer and organic: animal or green manure) on δ15N in blood plasma. At study baseline, plasma δ15N was +9.34 ± 0.29‰ (mean ± standard deviation). After 12 days intervention with a diet based on crops fertilized with animal manure, plasma δ15N was shifted by +0.27 ± 0.04‰ (mean ± standard error) compared to synthetic fertilization and by +0.22 ± 0.04‰ compared to fertilization with green manure (both p < 0.0001). Accordingly, differences in the δ15N values between fertilizers are propagated to the blood plasma of human consumers. The results indicate a need to consider agricultural practices when using δ15N as a dietary biomarker.

AB - The stable nitrogen isotope ratio δ15N is used as a marker of dietary protein sources in blood. Crop fertilization strategies affect δ15N in plant foods. In a double-blinded randomized cross-over dietary intervention trial with 33 participants, we quantified the effect of fertilizer type (conventional: synthetic fertilizer and organic: animal or green manure) on δ15N in blood plasma. At study baseline, plasma δ15N was +9.34 ± 0.29‰ (mean ± standard deviation). After 12 days intervention with a diet based on crops fertilized with animal manure, plasma δ15N was shifted by +0.27 ± 0.04‰ (mean ± standard error) compared to synthetic fertilization and by +0.22 ± 0.04‰ compared to fertilization with green manure (both p < 0.0001). Accordingly, differences in the δ15N values between fertilizers are propagated to the blood plasma of human consumers. The results indicate a need to consider agricultural practices when using δ15N as a dietary biomarker.

KW - Faculty of Science

KW - Dietary protein

KW - Fertilizer type

KW - Organic food

KW - Production systems

KW - Stable nitrogen isotopes

U2 - 10.1021/acs.jafc.1c04418

DO - 10.1021/acs.jafc.1c04418

M3 - Journal article

C2 - 35263104

VL - 70

SP - 3391

EP - 3399

JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

SN - 0021-8561

IS - 11

ER -

ID: 300083197