Enhanced fatty acid oxidation and FATP4 protein expression after endurance exercise training in human skeletal muscle
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Enhanced fatty acid oxidation and FATP4 protein expression after endurance exercise training in human skeletal muscle. / Jeppesen, Jacob; Jordy, Andreas B; Sjøberg, Kim A; Füllekrug, Joachim; Stahl, Andreas; Nybo, Lars; Kiens, Bente.
I: P L o S One, Bind 7, Nr. 1, 2012, s. e29391.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Enhanced fatty acid oxidation and FATP4 protein expression after endurance exercise training in human skeletal muscle
AU - Jeppesen, Jacob
AU - Jordy, Andreas B
AU - Sjøberg, Kim A
AU - Füllekrug, Joachim
AU - Stahl, Andreas
AU - Nybo, Lars
AU - Kiens, Bente
N1 - CURIS 2012 5200 023
PY - 2012
Y1 - 2012
N2 - FATP1 and FATP4 appear to be important for the cellular uptake and handling of long chain fatty acids (LCFA). These findings were obtained from loss- or gain of function models. However, reports on FATP1 and FATP4 in human skeletal muscle are limited. Aerobic training enhances lipid oxidation; however, it is not known whether this involves up-regulation of FATP1 and FATP4 protein. Therefore, the aim of this project was to investigate FATP1 and FATP4 protein expression in the vastus lateralis muscle from healthy human individuals and to what extent FATP1 and FATP4 protein expression were affected by an increased fuel demand induced by exercise training. Eight young healthy males were recruited to the study. All subjects were non smokers and did not participate in regular physical activity (
AB - FATP1 and FATP4 appear to be important for the cellular uptake and handling of long chain fatty acids (LCFA). These findings were obtained from loss- or gain of function models. However, reports on FATP1 and FATP4 in human skeletal muscle are limited. Aerobic training enhances lipid oxidation; however, it is not known whether this involves up-regulation of FATP1 and FATP4 protein. Therefore, the aim of this project was to investigate FATP1 and FATP4 protein expression in the vastus lateralis muscle from healthy human individuals and to what extent FATP1 and FATP4 protein expression were affected by an increased fuel demand induced by exercise training. Eight young healthy males were recruited to the study. All subjects were non smokers and did not participate in regular physical activity (
U2 - 10.1371/journal.pone.0029391
DO - 10.1371/journal.pone.0029391
M3 - Journal article
C2 - 22235293
VL - 7
SP - e29391
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 1
ER -
ID: 37588184