A novel treatment for weight reduction by the recombinant "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin"
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
Obesity is a major health problem across the world, but there are few ways to effectively treat or manage it in the long term. Researchers are searching for more convenient, cost-effective and noninvasive therapies for overweight and obese people. Recent studies have illustrated that the microbiome of the body's different organs can be used as a vehicle for in-situ gene therapy. We suggest that the recombinant form of "Pichia pastoris" yeast expressing the hybrid protein of "irisin-furin-transferrin" under the control of the enolase 1 promoter is a new nutraceutical strategy to absorb fewer calories from intestinal nutrients, and induce a higher metabolic rate to expend more calories, similar to that from engaging in physical activity. By comparison, this method can be a long-term, noninvasive treatment and can be used for obese patients who have movement limitations.
Originalsprog | Engelsk |
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Tidsskrift | Journal of Integrative Medicine |
Vol/bind | 14 |
Udgave nummer | 1 |
Sider (fra-til) | 1-4 |
Antal sider | 4 |
ISSN | 2095-4964 |
DOI | |
Status | Udgivet - 2016 |
Eksternt udgivet | Ja |
Bibliografisk note
(Ekstern)
ID: 248338664