One day of moderate energy deficit reduces fasting and postprandial triacylglycerolemia in women: the role of calorie restriction and exercise
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One day of moderate energy deficit reduces fasting and postprandial triacylglycerolemia in women: the role of calorie restriction and exercise. / Maraki, Maria; Magkos, Faidon; Christodoulou, Nektarios; Aggelopoulou, Niki; Skenderi, Katerina P; Panagiotakos, Demosthenes; Kavouras, Stavros A; Sidossis, Labros S.
In: Clinical Nutrition, Vol. 29, No. 4, 2010, p. 459-463.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - One day of moderate energy deficit reduces fasting and postprandial triacylglycerolemia in women: the role of calorie restriction and exercise
AU - Maraki, Maria
AU - Magkos, Faidon
AU - Christodoulou, Nektarios
AU - Aggelopoulou, Niki
AU - Skenderi, Katerina P
AU - Panagiotakos, Demosthenes
AU - Kavouras, Stavros A
AU - Sidossis, Labros S
N1 - Copyright 2009 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
PY - 2010
Y1 - 2010
N2 - Background & aims: Fasting and postprandial hypertriacylglycerolemia are important cardiovascular risk factors in women. We sought to examine the effects of acute (1 day), moderate (∼ 2 MJ) energy deficit induced by calorie restriction, exercise, or combination of both on fasting and postprandial triacylglycerol (TAG) metabolism in women.Methods: Six healthy premenopausal women performed four oral fat tolerance tests in the morning after a day of a) rest (control), b) calorie restriction (∼ 2 MJ), c) exercise (net deficit of ∼ 2 MJ) and d) calorie restriction-plus-exercise (total energy deficit of ∼ 2 MJ).Results: All energy deficit trials significantly reduced fasting and postprandial total plasma TAG concentrations by 15-23% and 12-23%, respectively, and triacylglycerol-rich lipoprotein TAG concentrations by 37-43% and 25-39%, respectively, compared with the control condition (P < 0.05). Postprandial, but not fasting, total TAG concentrations were approximately 12% lower after exercise compared with diet-induced energy deficit (P = 0.05).Conclusions: Acute, moderate energy deficit independently of its origin (i.e. diet or exercise or combination of both) reduces fasting and postprandial triacylglycerolemia in women. Exercise elicits a somewhat greater effect than calorie restriction in the postprandial state. The acute effect of diet and exercise should be taken into account when studying the long-term effects of weight loss and exercise training on TAG metabolism.
AB - Background & aims: Fasting and postprandial hypertriacylglycerolemia are important cardiovascular risk factors in women. We sought to examine the effects of acute (1 day), moderate (∼ 2 MJ) energy deficit induced by calorie restriction, exercise, or combination of both on fasting and postprandial triacylglycerol (TAG) metabolism in women.Methods: Six healthy premenopausal women performed four oral fat tolerance tests in the morning after a day of a) rest (control), b) calorie restriction (∼ 2 MJ), c) exercise (net deficit of ∼ 2 MJ) and d) calorie restriction-plus-exercise (total energy deficit of ∼ 2 MJ).Results: All energy deficit trials significantly reduced fasting and postprandial total plasma TAG concentrations by 15-23% and 12-23%, respectively, and triacylglycerol-rich lipoprotein TAG concentrations by 37-43% and 25-39%, respectively, compared with the control condition (P < 0.05). Postprandial, but not fasting, total TAG concentrations were approximately 12% lower after exercise compared with diet-induced energy deficit (P = 0.05).Conclusions: Acute, moderate energy deficit independently of its origin (i.e. diet or exercise or combination of both) reduces fasting and postprandial triacylglycerolemia in women. Exercise elicits a somewhat greater effect than calorie restriction in the postprandial state. The acute effect of diet and exercise should be taken into account when studying the long-term effects of weight loss and exercise training on TAG metabolism.
KW - Adult
KW - Caloric Restriction/adverse effects
KW - Cardiovascular Diseases/epidemiology
KW - Combined Modality Therapy
KW - Cross-Over Studies
KW - Diet, Reducing/adverse effects
KW - Exercise/physiology
KW - Fasting
KW - Female
KW - Humans
KW - Hypertriglyceridemia/blood
KW - Lipoproteins/blood
KW - Motor Activity/physiology
KW - Physical Endurance/physiology
KW - Postprandial Period
KW - Premenopause
KW - Risk Factors
KW - Triglycerides/blood
KW - Young Adult
U2 - 10.1016/j.clnu.2009.10.007
DO - 10.1016/j.clnu.2009.10.007
M3 - Journal article
C2 - 19926367
VL - 29
SP - 459
EP - 463
JO - Clinical Nutrition
JF - Clinical Nutrition
SN - 0261-5614
IS - 4
ER -
ID: 290670500