Effect of β-glucan supplementation on acute postprandial changes in fatty acid profile of lymph and serum in pigs
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Triglycerides are absorbed by the lymphatic system and have various functions in the body. It has been shown that some types of β-glucans have a positive effect on the systemic concentrations of cholesterol and lipid, presumably through interference with the absorption of lipid and/or reabsorption of bile acids. In the current study we investigated the acute effects of ingesting 2 g of β-glucan concentrates derived from barley β-(1→3)(1→4)-D-glucan or yeast β-(1→3)(1→6)-D-glucan on fatty acid content and composition in lymph and serum of 10 female pigs (initial weight 34.7±1.1 kg) fitted with a permanent catheter in the jejunal lymphatic trunk in a cross-over design. Lymph was collected continuously for 8 h followed by a spot sample taken 24 h after. A significant effect of time after feeding was observed for all fatty acids in serum and for 18:0, 18:2ω6 and 18:3ω3 in lymph, but a significant effect of β-glucan was only observed for 14:0 (p=0.049) and 22:6ω3 (p=0.048) in lymph and 18:0 (p=0.019) in serum. While the concentration of dietary fatty acids increased postprandially in lymph, the concentration of arachidonic and docahexanoic acid tended to decrease. Furthermore, there was a drop in concentration of all fatty acid in serum 1 h after the meal.
Original language | English |
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Journal | International Journal of Molecular Sciences |
Volume | 15 |
Issue number | 8 |
Pages (from-to) | 13881-13891 |
Number of pages | 11 |
ISSN | 1424-6783 |
DOIs | |
Publication status | Published - 2014 |
Externally published | Yes |
- Animals, Dietary Supplements, Fatty Acids/blood, Female, Lymph/metabolism, Swine, Time Factors, beta-Glucans/pharmacology
Research areas
ID: 290678459