Central and peripheral blood flow during exercise with a continuous-flow left ventricular assist device: constant versus increasing pump speed: a pilot study

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Central and peripheral blood flow during exercise with a continuous-flow left ventricular assist device: constant versus increasing pump speed: a pilot study. / Brassard, Patrice; Jensen, Annette S; Nordsborg, Nikolai; Gustafsson, Finn; Møller, Jacob E; Hassager, Christian; Boesgaard, Søren; Hansen, Peter Bo; Olsen, Peter Skov; Sander, Kåre; Secher, Niels H; Madsen, Per Lav.

In: Circulation. Heart Failure, Vol. 4, No. 5, 2011, p. 554-560.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Brassard, P, Jensen, AS, Nordsborg, N, Gustafsson, F, Møller, JE, Hassager, C, Boesgaard, S, Hansen, PB, Olsen, PS, Sander, K, Secher, NH & Madsen, PL 2011, 'Central and peripheral blood flow during exercise with a continuous-flow left ventricular assist device: constant versus increasing pump speed: a pilot study', Circulation. Heart Failure, vol. 4, no. 5, pp. 554-560. https://doi.org/10.1161/CIRCHEARTFAILURE.110.958041

APA

Brassard, P., Jensen, A. S., Nordsborg, N., Gustafsson, F., Møller, J. E., Hassager, C., Boesgaard, S., Hansen, P. B., Olsen, P. S., Sander, K., Secher, N. H., & Madsen, P. L. (2011). Central and peripheral blood flow during exercise with a continuous-flow left ventricular assist device: constant versus increasing pump speed: a pilot study. Circulation. Heart Failure, 4(5), 554-560. https://doi.org/10.1161/CIRCHEARTFAILURE.110.958041

Vancouver

Brassard P, Jensen AS, Nordsborg N, Gustafsson F, Møller JE, Hassager C et al. Central and peripheral blood flow during exercise with a continuous-flow left ventricular assist device: constant versus increasing pump speed: a pilot study. Circulation. Heart Failure. 2011;4(5):554-560. https://doi.org/10.1161/CIRCHEARTFAILURE.110.958041

Author

Brassard, Patrice ; Jensen, Annette S ; Nordsborg, Nikolai ; Gustafsson, Finn ; Møller, Jacob E ; Hassager, Christian ; Boesgaard, Søren ; Hansen, Peter Bo ; Olsen, Peter Skov ; Sander, Kåre ; Secher, Niels H ; Madsen, Per Lav. / Central and peripheral blood flow during exercise with a continuous-flow left ventricular assist device: constant versus increasing pump speed: a pilot study. In: Circulation. Heart Failure. 2011 ; Vol. 4, No. 5. pp. 554-560.

Bibtex

@article{d3035568d42e40f389eb19cbff219050,
title = "Central and peripheral blood flow during exercise with a continuous-flow left ventricular assist device: constant versus increasing pump speed: a pilot study",
abstract = "Background- End-stage heart failure is associated with impaired cardiac output (CO) and organ blood flow. We determined whether CO and peripheral perfusion are maintained during exercise in patients with an axial-flow left ventricular assist device (LVAD) and whether an increase in LVAD pump speed with work rate would increase organ blood flow. Methods and Results- Invasively determined CO and leg blood flow and Doppler-determined cerebral perfusion were measured during 2 incremental cycle exercise tests on the same day in 8 patients provided with a HeartMate II LVAD. In random order, patients exercised both with a constant (˜9775 rpm) and with an increasing pump speed (+400 rpm per exercise stage). At 60 W, the elevation in CO was more pronounced with increased pump speed (8.7±0.6 versus 8.1±1.1 L · min(-1); mean±SD; P=0.05), but at maximal exercise increases in CO (from 7.0±0.9 to 13.6±2.5 L · min(-1); P",
author = "Patrice Brassard and Jensen, {Annette S} and Nikolai Nordsborg and Finn Gustafsson and M{\o}ller, {Jacob E} and Christian Hassager and S{\o}ren Boesgaard and Hansen, {Peter Bo} and Olsen, {Peter Skov} and K{\aa}re Sander and Secher, {Niels H} and Madsen, {Per Lav}",
note = "CURIS 2011 5200 091",
year = "2011",
doi = "10.1161/CIRCHEARTFAILURE.110.958041",
language = "English",
volume = "4",
pages = "554--560",
journal = "Circulation: Heart Failure",
issn = "1941-3289",
publisher = "Lippincott Williams & Wilkins",
number = "5",

}

RIS

TY - JOUR

T1 - Central and peripheral blood flow during exercise with a continuous-flow left ventricular assist device: constant versus increasing pump speed: a pilot study

AU - Brassard, Patrice

AU - Jensen, Annette S

AU - Nordsborg, Nikolai

AU - Gustafsson, Finn

AU - Møller, Jacob E

AU - Hassager, Christian

AU - Boesgaard, Søren

AU - Hansen, Peter Bo

AU - Olsen, Peter Skov

AU - Sander, Kåre

AU - Secher, Niels H

AU - Madsen, Per Lav

N1 - CURIS 2011 5200 091

PY - 2011

Y1 - 2011

N2 - Background- End-stage heart failure is associated with impaired cardiac output (CO) and organ blood flow. We determined whether CO and peripheral perfusion are maintained during exercise in patients with an axial-flow left ventricular assist device (LVAD) and whether an increase in LVAD pump speed with work rate would increase organ blood flow. Methods and Results- Invasively determined CO and leg blood flow and Doppler-determined cerebral perfusion were measured during 2 incremental cycle exercise tests on the same day in 8 patients provided with a HeartMate II LVAD. In random order, patients exercised both with a constant (˜9775 rpm) and with an increasing pump speed (+400 rpm per exercise stage). At 60 W, the elevation in CO was more pronounced with increased pump speed (8.7±0.6 versus 8.1±1.1 L · min(-1); mean±SD; P=0.05), but at maximal exercise increases in CO (from 7.0±0.9 to 13.6±2.5 L · min(-1); P

AB - Background- End-stage heart failure is associated with impaired cardiac output (CO) and organ blood flow. We determined whether CO and peripheral perfusion are maintained during exercise in patients with an axial-flow left ventricular assist device (LVAD) and whether an increase in LVAD pump speed with work rate would increase organ blood flow. Methods and Results- Invasively determined CO and leg blood flow and Doppler-determined cerebral perfusion were measured during 2 incremental cycle exercise tests on the same day in 8 patients provided with a HeartMate II LVAD. In random order, patients exercised both with a constant (˜9775 rpm) and with an increasing pump speed (+400 rpm per exercise stage). At 60 W, the elevation in CO was more pronounced with increased pump speed (8.7±0.6 versus 8.1±1.1 L · min(-1); mean±SD; P=0.05), but at maximal exercise increases in CO (from 7.0±0.9 to 13.6±2.5 L · min(-1); P

U2 - 10.1161/CIRCHEARTFAILURE.110.958041

DO - 10.1161/CIRCHEARTFAILURE.110.958041

M3 - Journal article

C2 - 21765126

VL - 4

SP - 554

EP - 560

JO - Circulation: Heart Failure

JF - Circulation: Heart Failure

SN - 1941-3289

IS - 5

ER -

ID: 34409226