TY - RPRT

T1 - EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to olive leaf (Olea europaea L.) water extract and increase in glucose tolerance pursuant to Article 13(5) of Regulation (EC) No 1924/2006.

AU - Publication, EFSA

AU - Tetens, Inge

PY - 2014

Y1 - 2014

N2 - Following an application from Comvita New Zealand Limited, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to olive (Olea europaea L.) leaf water extract and increase in glucose tolerance. The food that is the subject of the health claim, olive leaf water extract standardised by its content of oleuropein, is sufficiently characterised. The claimed effect, an increase in glucose tolerance, is a beneficial physiological effect as long as serum insulin concentrations are not disproportionately increased. One human intervention study showed an increase in glucose tolerance without disproportionate increase in insulin concentrations after daily consumption of the olive leaf water extract for 12 weeks under the conditions of use proposed by the applicant. However, the results have not been replicated in other studies, and no evidence has been provided in relation to the mechanism by which the olive leaf water extract could exert the claimed effect. The scientific evidence is insufficient to establish a cause and effect relationship between the consumption of olive leaf water extract and an increase in glucose tolerance.

AB - Following an application from Comvita New Zealand Limited, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to olive (Olea europaea L.) leaf water extract and increase in glucose tolerance. The food that is the subject of the health claim, olive leaf water extract standardised by its content of oleuropein, is sufficiently characterised. The claimed effect, an increase in glucose tolerance, is a beneficial physiological effect as long as serum insulin concentrations are not disproportionately increased. One human intervention study showed an increase in glucose tolerance without disproportionate increase in insulin concentrations after daily consumption of the olive leaf water extract for 12 weeks under the conditions of use proposed by the applicant. However, the results have not been replicated in other studies, and no evidence has been provided in relation to the mechanism by which the olive leaf water extract could exert the claimed effect. The scientific evidence is insufficient to establish a cause and effect relationship between the consumption of olive leaf water extract and an increase in glucose tolerance.

KW - Olive leaf water extract

KW - Oleuropein

KW - Glucose tolerance

KW - Health claim

U2 - 10.2903/j.efsa.2014.3655

DO - 10.2903/j.efsa.2014.3655

M3 - Report

BT - EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to olive leaf (Olea europaea L.) water extract and increase in glucose tolerance pursuant to Article 13(5) of Regulation (EC) No 1924/2006.

PB - Europen Food Safety Authority

ER -