Contraction-associated translocation of protein kinase C in rat skeletal muscle
Research output: Contribution to journal › Journal article › Research › peer-review
Electrical stimulation of the sciatic nerve of the anaesthetized rat in vivo led to a time-dependent translocation of protein kinase C from the muscle cytosol to the particulate fraction. Maximum activity of protein kinase C in the particulate fraction occurred after 2 min of intermittent short tetanic contractions of the gastrocnemius-plantaris-soleus muscle group and coincided with the loss of activity from the cytosol. Translocation of protein kinase C may imply a role for this kinase in contraction-initiated changes in muscle metabolism.
|Number of pages||5|
|Publication status||Published - 1987|
- Animals, Biological Transport, Calcium, Cytosol, Kinetics, Male, Muscle Contraction, Muscles, Phospholipids, Protein Kinase C, Rats, Rats, Inbred Strains, Subcellular Fractions