Thomas Elbenhardt Jensen
Associate Professor
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Microtubule-mediated GLUT4 trafficking is disrupted in insulin resistant skeletal muscle
Knudsen, Jonas Roland, Persson, Kaspar Wredstrøm, Henriquez-Olguín, Carlos, Li, Z., Di Leo, N., Raun, Steffen Henning, Hingst, J. R., Trouillon, R., Wohlwend, M., Wojtaszewski, Jørgen F P, Gijs, M. A. M. & Jensen, Thomas Elbenhardt, 22 Sep 2022, bioRxiv, p. 1-55, 55 p.Research output: Working paper › Preprint › Research
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Microtubule-mediated GLUT4 trafficking is disrupted in insulin resistant skeletal muscle
Knudsen, Jonas Roland, Persson, K. W., Henriquez-Olguín, Carlos, Li, Z., Di Leo, N., Hesselager, S. A., Raun, Steffen Henning, Hingst, J. R., Trouillon, R., Wohlwend, M., Wojtaszewski, Jørgen F P, Gijs, M. A. M. & Jensen, Thomas Elbenhardt, 2023, In: eLife. 12, 24 p., e83338.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple signalling pathways redundantly control glucose transporter GLUT4 gene transcription in skeletal muscle
Murgia, M., Jensen, Thomas Elbenhardt, Cusinato, M., Garcia, M., Richter, Erik A. & Schiaffino, S., 2009, In: Journal of Physiology. 587, 17, p. 4319-4327 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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NOX2 deficiency exacerbates diet-induced obesity and impairs molecular training adaptations in skeletal muscle
Henriquez-Olguín, Carlos, Meneses Valdés, Roberto Andrés, Raun, Steffen Henning, Gallero, S., Knudsen, Jonas Roland, Li, Z., Li, J., Sylow, Lykke, Jaimovich, E. & Jensen, Thomas Elbenhardt, 2023, In: Redox Biology. 65, 12 p., 102842.Research output: Contribution to journal › Journal article › Research › peer-review
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PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain
Jensen, Thomas Elbenhardt, Ross, F. A., Kleinert, Maximilian, Sylow, Lykke, Knudsen, Jonas Roland, Gowans, G. J., Hardie, D. G. & Richter, Erik A., 2015, In: Biochemical Journal. 467, 3, p. 461-472 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements
Li, Z., Rasmussen, M. L., Li, J., Henriquez-Olguín, Carlos, Knudsen, Jonas Roland, Madsen, A. B., Sanchez-Quant, E., Kleinert, Maximilian & Jensen, Thomas Elbenhardt, 2018, In: Molecular Metabolism. 17, p. 112-121 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phosphoproteomic identification of Xin as a novel requirement for skeletal muscle disuse atrophy
Li, Z., Jensen, P., Abrigo, J., Henriquez-Olguín, Carlos, Gingrich, M., Rytter, N., Gliemann, Lasse, Richter, Erik A., Hawke, T., Cabello-Verrugio, C., Larsen, M. R. & Jensen, Thomas Elbenhardt, 28 May 2019, (bioRxiv).Research output: Working paper › Preprint › Research
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Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function
Blazev, R., Carl, C. S., Ng, Y-K., Molendijk, J., Voldstedlund, C. T., Zhao, Y., Xiao, D., Kueh, A. J., Miotto, P. M., Haynes, V. R., Hardee, J. P., Chung, J. D., McNamara, J. W., Qian, H., Gregorevic, P., Oakhill, J. S., Herold, M. J., Jensen, T. E., Lisowski, L., Lynch, G. S. & 6 others, , 2022, In: Cell Metabolism. 34, 10, p. 1561-1577.e9 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction
Jensen, Thomas Elbenhardt, Rose, A. J., Jørgensen, S. B., Brandt, N., Schjerling, P., Wojtaszewski, Jørgen F P & Richter, Erik A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 5, p. E1308-E1317 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prior exercise in humans redistributes intramuscular GLUT4 and enhances insulin-stimulated sarcolemmal and endosomal GLUT4 translocation
Knudsen, Jonas Roland, Steenberg, D. E., Hingst, J. R., Hodgson, L. R., Henriquez-Olguín, Carlos, Li, Z., Kiens, Bente, Richter, Erik A., Wojtaszewski, Jørgen F P, Verkade, P. & Jensen, Thomas Elbenhardt, 2020, In: Molecular Metabolism. 39, 9 p., 100998.Research output: Contribution to journal › Journal article › Research › peer-review
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Pro-inflammatory macrophages increase in skeletal muscle of high fat-fed mice and correlate with metabolic risk markers in humans
Fink, L. N., Costford, S. R., Lee, Y. S., Jensen, Thomas Elbenhardt, Bilan, P. J., Oberbach, A., Blüher, M., Olefsky, J. M., Sams, A. & Klip, A., 2014, In: Obesity. 22, 3, p. 747-757 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein kinase C {alpha} activity is important for contraction-induced FXYD1 phosphorylation in skeletal muscle
Thomassen, Martin, Rose, A. J., Jensen, Thomas Elbenhardt, Maarbjerg, S. J., Bune, L. T., Leitges, M., Richter, Erik A., Bangsbo, Jens & Nordsborg, Nikolai Baastrup, 2011, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 301, 6, p. R1808-R1814 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training
Kleinert, Maximilian, Parker, B. L., Jensen, Thomas Elbenhardt, Raun, Steffen Henning, Pham, P., Han, X., James, D. E., Richter, Erik A. & Sylow, Lykke, 2018, In: Scientific Reports. 8, 11 p., 10723.Research output: Contribution to journal › Journal article › Research › peer-review
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RNA-bound PGC-1α controls gene expression in liquid-like nuclear condensates
Pérez-Schindler, J., Kohl, B., Schneider-Heieck, K., Leuchtmann, A. B., Henriquez-Olguín, Carlos, Adak, V., Maier, G., Delezie, J., Sakoparnig, T., Vargas-Fernández, E., Karrer-Cardel, B., Ritz, D., Schmidt, A., Hondele, M., Jensen, Thomas Elbenhardt, Hiller, S. & Handschin, C., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 36, 11 p., e2105951118.Research output: Contribution to journal › Journal article › Research › peer-review
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Rac1 and AMPK account for the majority of muscle glucose uptake stimulated by ex vivo contraction but not in vivo exercise
Sylow, Lykke, Møller, Lisbeth L V, Kleinert, Maximilian, D'Hulst, G., De Groote, E., Schjerling, P., Steinberg, G. R., Jensen, Thomas Elbenhardt & Richter, Erik A., 2017, In: Diabetes. 66, 6, p. 1548-1559 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice
Sylow, Lykke, Laurent, I., Kleinert, Maximilian, Møller, Lisbeth L V, Ploug, Thorkil, Schjerling, Peter, Bilan, P. J., Klip, A., Jensen, Thomas Elbenhardt & Richter, Erik A., 2016, In: Journal of Physiology. 594, 17, p. 4997-5008 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rac1 in muscle is dispensable for improved insulin action after exercise in mice
Sylow, Lykke, Møller, Lisbeth L V, D'Hulst, G., Schjerling, P., Jensen, Thomas Elbenhardt & Richter, Erik A., 2016, In: Endocrinology. 157, 8, p. 3009-3015 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rac1 is a novel regulator of contraction-stimulated glucose uptake in skeletal muscle
Sylow, Lykke, Jensen, Thomas Elbenhardt, Kleinert, Maximilian, Mouatt, J. R., Maarbjerg, S. J., Jeppesen, J. F., Prats Gavalda, Clara, Chiu, T. T., Boguslavsky, S., Klip, A., Schjerling, Peter & Richter, Erik A., 2013, In: Diabetes. 62, 4, p. 1139-1151 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of Akt
Raun, Steffen Henning, Ali, Mona Sadek, Kjøbsted, Rasmus, Møller, Lisbeth L V, Federspiel, M. A., Richter, Erik A., Jensen, Thomas Elbenhardt & Sylow, Lykke, 2018, In: Journal of Physiology. 596, 12, p. 2283-2299 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle
Sylow, Lykke, Jensen, Thomas Elbenhardt, Kleinert, Maximilian, Højlund, K., Kiens, Bente, Wojtaszewski, Jørgen F P, Prats Gavalda, Clara, Schjerling, P. & Richter, Erik A., 2013, In: Diabetes. 62, 6, p. 1865-1875 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle
Chiu, T. T., Jensen, Thomas Elbenhardt, Sylow, Lykke, Richter, Erik A. & Klip, A., 2011, In: Cellular Signalling. 23, 10, p. 1546-1554 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Rac1- a novel regulator of contraction-stimulated glucose uptake in skeletal muscle
Sylow, Lykke, Møller, L. L. V., Kleinert, Maximilian, Richter, Erik A. & Jensen, Thomas Elbenhardt, 2014, In: Experimental Physiology. 99, 12, p. 1574-1580 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rapamycin and mTORC2 inhibition synergistically reduce contraction-stimulated muscle protein synthesis
Ogasawara, R., Knudsen, Jonas Roland, Li, J., Ato, S. & Jensen, Thomas Elbenhardt, 2020, In: Journal of Physiology. 598, 23, p. 5453-5466 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reducing the mitochondrial oxidative burden alleviates lipid-induced insulin resistance in human skeletal muscle
Fiorenza, Matteo, Onslev, J., Henriquez-Olguín, Carlos, Jensen, Thomas Elbenhardt, Wojtaszewski, Jørgen F P, Hostrup, Morten & Bangsbo, Jens, 12 Apr 2023, bioRxiv, p. 1-39, 39 p.Research output: Working paper › Preprint › Research
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Regulation of AMP-activated protein kinase by LKB1 and CaMKK in adipocytes
Gormand, A., Henriksson, E., Ström, K., Jensen, Thomas Elbenhardt, Sakamoto, Kei & Göransson, O., 2011, In: Journal of Cellular Biochemistry. 112, 5, p. 1364-1375 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation
Fritzen, Andreas Mæchel, Madsen, A. L. B., Kleinert, Maximilian, Treebak, Jonas Thue, Lundsgaard, Anne-Marie, Jensen, Thomas Elbenhardt, Richter, Erik A., Wojtaszewski, Jørgen F P, Kiens, Bente & Frøsig, C., 2016, In: Journal of Physiology. 594, 3, p. 745-761 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of glucose and glycogen metabolism during and after exercise
Jensen, Thomas Elbenhardt & Richter, Erik A., 2012, In: Journal of Physiology. 590, 5, p. 1069-1076 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Reply from Lykke Sylow, Lisbeth L. V. Møller, Maximilian Kleinert, Erik A. Richter and Thomas E. Jensen
Sylow, Lykke, Møller, Lisbeth L V, Kleinert, Maximilian, Richter, Erik A. & Jensen, Thomas Elbenhardt, 2015, In: Journal of Physiology. 593, 9, p. 2239-2240 2 p.Research output: Contribution to journal › Comment/debate › Research
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Resistance exercise-induced hypertrophy: A potential role for rapamycin-insensitive mTOR
Ogasawara, R., Jensen, Thomas Elbenhardt, Goodman, C. A. & Hornberger, T. A., 2019, In: Exercise and Sport Sciences Reviews. 47, 3, p. 188-194Research output: Contribution to journal › Review › Research › peer-review
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Role of AMPK in regulation of LC3 lipidation as a marker of autophagy in skeletal muscle
Fritzen, Andreas Mæchel, Frøsig, C., Jeppesen, J. F., Jensen, Thomas Elbenhardt, Lundsgaard, Anne-Marie, Serup, A. K. L., Schjerling, Peter, Proud, C. G., Richter, Erik A. & Kiens, Bente, 2016, In: Cellular Signalling. 28, 6, p. 663-674 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of AMPK in skeletal muscle gene adaptation in relation to exercise
Jørgensen, S. B., Jensen, Thomas Elbenhardt & Richter, Erik A., 2007, In: Applied Physiology, Nutrition and Metabolism. 32, 5, p. 904-911 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Skeletal muscle-specific activation of Gq signaling maintains glucose homeostasis
Bone, D. B. J., Meister, J., Knudsen, Jonas Roland, Dattaroy, D., Cohen, A., Lee, R., Lu, H., Metzger, D., Jensen, Thomas Elbenhardt & Wess, J., 2019, In: Diabetes. 68, 6, p. 1341-1352 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stretch-stimulated glucose transport in skeletal muscle is regulated by Rac1
Sylow, Lykke, Møller, L. L. V., Kleinert, Maximilian, Richter, Erik A. & Jensen, Thomas Elbenhardt, 2015, In: Journal of Physiology. 593, 3, p. 645-656 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TLR2 controls intestinal carcinogen detoxication by CYP1A1
Do, K. N., Fink, L. N., Jensen, Thomas Elbenhardt, Gautier, L. & Parlesak, Alexandr, 2012, In: P L o S One. 7, 3, 7 p., e32309.Research output: Contribution to journal › Journal article › Research › peer-review
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The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action
Møller, Lisbeth L V, Ali, Mona Sadek, Davey, J., Raun, Steffen Henning, Andersen, Nicoline Resen, Long, J. Z., Qian, H., Jeppesen, J. F., Henriquez-Olguín, Carlos, Frank, E., Jensen, Thomas Elbenhardt, Højlund, K., Wojtaszewski, Jørgen F P, Nielsen, J., Chiu, T. T., Jedrychowski, M. P., Gregorevic, P., Klip, A., Richter, Erik A. & Sylow, Lykke, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 27, 12 p., e2211041120.Research output: Contribution to journal › Journal article › Research › peer-review
The Rho-guanine nucleotide exchange factor PDZ-RhoGEF governs susceptibility to diet-induced obesity and type 2 diabetes
Chang, Y., Pownall, S., Jensen, Thomas Elbenhardt, Mouaaz, S., Foltz, W., Zhou, L., Liadis, N., Woo, M., Hao, Z., Dutt, P., Bilan, P. J., Klip, A., Mak, T. & Stambolic, V., 2015, In: eLife. 4, 24 p., e06011.Research output: Contribution to journal › Journal article › Research › peer-review
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The ULK1/2 and AMPK inhibitor SBI-0206965 blocks AICAR and insulin-stimulated glucose transport
Knudsen, Jonas Roland, Madsen, A. B., Persson, K. W., Henriquez-Olguín, Carlos, Li, Z. & Jensen, Thomas Elbenhardt, 2020, In: International Journal of Molecular Sciences . 21, 7, 10 p., 2344.Research output: Contribution to journal › Journal article › Research › peer-review
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The emerging roles of nicotinamide adenine dinucleotide phosphate oxidase 2 in skeletal muscle redox signaling and metabolism
Henriquez-Olguín, Carlos, Boronat, S., Cabello-Verrugio, C., Jaimovich, E., Hidalgo, E. & Jensen, Thomas Elbenhardt, 2019, In: Antioxidants & Redox Signaling. 31, 8, p. 1371-1410 40 p.Research output: Contribution to journal › Review › Research › peer-review
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The gut microbiome on a periodized low-protein diet is associated with improved metabolic health
Li, Z., Rasmussen, Torben Sølbeck, Rasmussen, M. L., Li, J., Henriquez-Olguín, Carlos, Kot, W., Nielsen, Dennis Sandris & Jensen, Thomas Elbenhardt, 2019, In: Frontiers in Microbiology. 10, 10 p., 709.Research output: Contribution to journal › Journal article › Research › peer-review
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The p21-activated kinase 2 (PAK2), but not PAK1, regulates contraction-stimulated skeletal muscle glucose transport
Møller, Lisbeth L V, Nielsen, I. L., Knudsen, Jonas Roland, Andersen, Nicoline Resen, Jensen, Thomas Elbenhardt, Sylow, Lykke & Richter, Erik A., 2020, In: Physiological Reports. 8, 12, 13 p., e14460.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of NADPH oxidase 2 in regulating IL-15 and PGC-1α gene expressions following a period of high intensity interval training: [The original title and the article is written in Persian!]
Baghersad Renani, L., Ravasi, A. A., Shabkhiz, F. & Jensen, Thomas Elbenhardt, 2019, In: Iranian Journal of Endocrinology and Metabolism. 20, 5, p. 263-272 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transparent and cell-guiding cellulose nanofiber 3D printing bioinks
Radeke, C., Pons, R., Mihajlovic, M., Knudsen, Jonas Roland, Butdayev, S., Kempen, Paul Joseph, Segeritz, C., Andresen, T. L., Pehmøller, C. K., Jensen, Thomas Elbenhardt & Lind, J. U., 2023, In: ACS Applied Materials and Interfaces. 15, 2, p. 2564-2577 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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When less is more: a simple Western blotting amendment allowing data acquisition on human single fibers
Jensen, Thomas Elbenhardt & Richter, Erik A., 2011, In: Journal of Applied Physiology. 110, 3, p. 583-584 2 p.Research output: Contribution to journal › Editorial › Research
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c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action
Molero, J. C., Jensen, Thomas Elbenhardt, Withers, P. C., Couzens, M., Herzog, H., Thien, C. B. F., Langdon, W. Y., Walder, K., Murphy, M. A., Bowtell, D. D. L., James, D. E. & Cooney, G. J., 2004, In: Journal of Clinical Investigation. 114, 9, p. 1326-1333 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle
Mori, T., Ato, S., Knudsen, Jonas Roland, Henriquez-Olguín, Carlos, Li, Z., Wakabayashi, K., Suginohara, T., Higashida, K., Tamura, Y., Nakazato, K., Jensen, Thomas Elbenhardt & Ogasawara, R., 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 321, 4, p. E551-E559 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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α-MSH stimulates glucose uptake in mouse muscle and phosphorylates Rab-GTPase-activating protein TBC1D1 independently of AMPK
Møller, C. L., Kjøbsted, Rasmus, Enriori, P. J., Jensen, Thomas Elbenhardt, Garcia-Rudaz, C., Litwak, S. A., Raun, K., Wojtaszewski, Jørgen F P, Wulff, B. S. & Cowley, M. A., 2016, In: P L o S One. 11, 7, 18 p., e0157027.Research output: Contribution to journal › Journal article › Research › peer-review
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β-actin shows limited mobility and is only required for supraphysiological insulin-stimulated glucose transport in young adult soleus muscle
Madsen, A. L. B., Knudsen, Jonas Roland, Henriquez-Olguín, Carlos, Angin, Y., Zaal, K. J., Sylow, Lykke, Schjerling, P., Ralston, E. & Jensen, Thomas Elbenhardt, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 315, 1, p. E110-E125 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4624
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AMPK and insulin action: Responses to ageing and high fat diet
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
258
downloads
α-MSH stimulates glucose uptake in mouse muscle and phosphorylates Rab-GTPase-activating protein TBC1D1 independently of AMPK
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
258
downloads
The gut microbiome on a periodized low-protein diet is associated with improved metabolic health
Research output: Contribution to journal › Journal article › Research › peer-review
Published