Thomas Elbenhardt Jensen

Thomas Elbenhardt Jensen

Associate Professor

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    ORCID: 0000-0001-6139-8268

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    1. Published

      Microtubule-mediated GLUT4 trafficking is disrupted in insulin resistant skeletal muscle

      Knudsen, Jonas Roland, Persson, Kaspar Wredstrøm, Henriquez-Olguín, Carlos, Li, Z., Di Leo, N., Raun, Steffen Henning, Hingst, J. R., Trouillon, R., Wohlwend, M., Wojtaszewski, Jørgen F P, Gijs, M. A. M. & Jensen, Thomas Elbenhardt, 22 Sep 2022, bioRxiv, p. 1-55, 55 p.

      Research output: Working paper › Preprint › Research

    2. Published

      Microtubule-mediated GLUT4 trafficking is disrupted in insulin resistant skeletal muscle

      Knudsen, Jonas Roland, Persson, K. W., Henriquez-Olguín, Carlos, Li, Z., Di Leo, N., Hesselager, S. A., Raun, Steffen Henning, Hingst, J. R., Trouillon, R., Wohlwend, M., Wojtaszewski, Jørgen F P, Gijs, M. A. M. & Jensen, Thomas Elbenhardt, 2023, In: eLife. 12, 24 p., e83338.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Multiple signalling pathways redundantly control glucose transporter GLUT4 gene transcription in skeletal muscle

      Murgia, M., Jensen, Thomas Elbenhardt, Cusinato, M., Garcia, M., Richter, Erik A. & Schiaffino, S., 2009, In: Journal of Physiology. 587, 17, p. 4319-4327 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      NOX2 deficiency exacerbates diet-induced obesity and impairs molecular training adaptations in skeletal muscle

      Henriquez-Olguín, Carlos, Meneses Valdés, Roberto Andrés, Raun, Steffen Henning, Gallero, S., Knudsen, Jonas Roland, Li, Z., Li, J., Sylow, Lykke, Jaimovich, E. & Jensen, Thomas Elbenhardt, 2023, In: Redox Biology. 65, 12 p., 102842.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain

      Jensen, Thomas Elbenhardt, Ross, F. A., Kleinert, Maximilian, Sylow, Lykke, Knudsen, Jonas Roland, Gowans, G. J., Hardie, D. G. & Richter, Erik A., 2015, In: Biochemical Journal. 467, 3, p. 461-472 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements

      Li, Z., Rasmussen, M. L., Li, J., Henriquez-Olguín, Carlos, Knudsen, Jonas Roland, Madsen, A. B., Sanchez-Quant, E., Kleinert, Maximilian & Jensen, Thomas Elbenhardt, 2018, In: Molecular Metabolism. 17, p. 112-121 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Phosphoproteomic identification of Xin as a novel requirement for skeletal muscle disuse atrophy

      Li, Z., Jensen, P., Abrigo, J., Henriquez-Olguín, Carlos, Gingrich, M., Rytter, N., Gliemann, Lasse, Richter, Erik A., Hawke, T., Cabello-Verrugio, C., Larsen, M. R. & Jensen, Thomas Elbenhardt, 28 May 2019, (bioRxiv).

      Research output: Working paper › Preprint › Research

    8. Published

      Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function

      Blazev, R., Carl, C. S., Ng, Y-K., Molendijk, J., Voldstedlund, C. T., Zhao, Y., Xiao, D., Kueh, A. J., Miotto, P. M., Haynes, V. R., Hardee, J. P., Chung, J. D., McNamara, J. W., Qian, H., Gregorevic, P., Oakhill, J. S., Herold, M. J., Jensen, T. E., Lisowski, L., Lynch, G. S. & 6 others, Dodd, G. T., Watt, M. J., Yang, P., Kiens, Bente, Richter, Erik A. & Parker, B. L., 2022, In: Cell Metabolism. 34, 10, p. 1561-1577.e9 27 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction

      Jensen, Thomas Elbenhardt, Rose, A. J., Jørgensen, S. B., Brandt, N., Schjerling, P., Wojtaszewski, Jørgen F P & Richter, Erik A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 5, p. E1308-E1317 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Prior exercise in humans redistributes intramuscular GLUT4 and enhances insulin-stimulated sarcolemmal and endosomal GLUT4 translocation

      Knudsen, Jonas Roland, Steenberg, D. E., Hingst, J. R., Hodgson, L. R., Henriquez-Olguín, Carlos, Li, Z., Kiens, Bente, Richter, Erik A., Wojtaszewski, Jørgen F P, Verkade, P. & Jensen, Thomas Elbenhardt, 2020, In: Molecular Metabolism. 39, 9 p., 100998.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Pro-inflammatory macrophages increase in skeletal muscle of high fat-fed mice and correlate with metabolic risk markers in humans

      Fink, L. N., Costford, S. R., Lee, Y. S., Jensen, Thomas Elbenhardt, Bilan, P. J., Oberbach, A., Blüher, M., Olefsky, J. M., Sams, A. & Klip, A., 2014, In: Obesity. 22, 3, p. 747-757 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Protein kinase C {alpha} activity is important for contraction-induced FXYD1 phosphorylation in skeletal muscle

      Thomassen, Martin, Rose, A. J., Jensen, Thomas Elbenhardt, Maarbjerg, S. J., Bune, L. T., Leitges, M., Richter, Erik A., Bangsbo, Jens & Nordsborg, Nikolai Baastrup, 2011, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 301, 6, p. R1808-R1814 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training

      Kleinert, Maximilian, Parker, B. L., Jensen, Thomas Elbenhardt, Raun, Steffen Henning, Pham, P., Han, X., James, D. E., Richter, Erik A. & Sylow, Lykke, 2018, In: Scientific Reports. 8, 11 p., 10723.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      RNA-bound PGC-1α controls gene expression in liquid-like nuclear condensates

      Pérez-Schindler, J., Kohl, B., Schneider-Heieck, K., Leuchtmann, A. B., Henriquez-Olguín, Carlos, Adak, V., Maier, G., Delezie, J., Sakoparnig, T., Vargas-Fernández, E., Karrer-Cardel, B., Ritz, D., Schmidt, A., Hondele, M., Jensen, Thomas Elbenhardt, Hiller, S. & Handschin, C., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 36, 11 p., e2105951118.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Rac1 and AMPK account for the majority of muscle glucose uptake stimulated by ex vivo contraction but not in vivo exercise

      Sylow, Lykke, Møller, Lisbeth L V, Kleinert, Maximilian, D'Hulst, G., De Groote, E., Schjerling, P., Steinberg, G. R., Jensen, Thomas Elbenhardt & Richter, Erik A., 2017, In: Diabetes. 66, 6, p. 1548-1559 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice

      Sylow, Lykke, Laurent, I., Kleinert, Maximilian, Møller, Lisbeth L V, Ploug, Thorkil, Schjerling, Peter, Bilan, P. J., Klip, A., Jensen, Thomas Elbenhardt & Richter, Erik A., 2016, In: Journal of Physiology. 594, 17, p. 4997-5008 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Rac1 in muscle is dispensable for improved insulin action after exercise in mice

      Sylow, Lykke, Møller, Lisbeth L V, D'Hulst, G., Schjerling, P., Jensen, Thomas Elbenhardt & Richter, Erik A., 2016, In: Endocrinology. 157, 8, p. 3009-3015 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Rac1 is a novel regulator of contraction-stimulated glucose uptake in skeletal muscle

      Sylow, Lykke, Jensen, Thomas Elbenhardt, Kleinert, Maximilian, Mouatt, J. R., Maarbjerg, S. J., Jeppesen, J. F., Prats Gavalda, Clara, Chiu, T. T., Boguslavsky, S., Klip, A., Schjerling, Peter & Richter, Erik A., 2013, In: Diabetes. 62, 4, p. 1139-1151 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of Akt

      Raun, Steffen Henning, Ali, Mona Sadek, Kjøbsted, Rasmus, Møller, Lisbeth L V, Federspiel, M. A., Richter, Erik A., Jensen, Thomas Elbenhardt & Sylow, Lykke, 2018, In: Journal of Physiology. 596, 12, p. 2283-2299 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle

      Sylow, Lykke, Jensen, Thomas Elbenhardt, Kleinert, Maximilian, Højlund, K., Kiens, Bente, Wojtaszewski, Jørgen F P, Prats Gavalda, Clara, Schjerling, P. & Richter, Erik A., 2013, In: Diabetes. 62, 6, p. 1865-1875 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle

      Chiu, T. T., Jensen, Thomas Elbenhardt, Sylow, Lykke, Richter, Erik A. & Klip, A., 2011, In: Cellular Signalling. 23, 10, p. 1546-1554 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    22. Published

      Rac1- a novel regulator of contraction-stimulated glucose uptake in skeletal muscle

      Sylow, Lykke, Møller, L. L. V., Kleinert, Maximilian, Richter, Erik A. & Jensen, Thomas Elbenhardt, 2014, In: Experimental Physiology. 99, 12, p. 1574-1580 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Rapamycin and mTORC2 inhibition synergistically reduce contraction-stimulated muscle protein synthesis

      Ogasawara, R., Knudsen, Jonas Roland, Li, J., Ato, S. & Jensen, Thomas Elbenhardt, 2020, In: Journal of Physiology. 598, 23, p. 5453-5466 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Reducing the mitochondrial oxidative burden alleviates lipid-induced insulin resistance in human skeletal muscle

      Fiorenza, Matteo, Onslev, J., Henriquez-Olguín, Carlos, Jensen, Thomas Elbenhardt, Wojtaszewski, Jørgen F P, Hostrup, Morten & Bangsbo, Jens, 12 Apr 2023, bioRxiv, p. 1-39, 39 p.

      Research output: Working paper › Preprint › Research

    25. Published

      Regulation of AMP-activated protein kinase by LKB1 and CaMKK in adipocytes

      Gormand, A., Henriksson, E., Ström, K., Jensen, Thomas Elbenhardt, Sakamoto, Kei & Göransson, O., 2011, In: Journal of Cellular Biochemistry. 112, 5, p. 1364-1375 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation

      Fritzen, Andreas Mæchel, Madsen, A. L. B., Kleinert, Maximilian, Treebak, Jonas Thue, Lundsgaard, Anne-Marie, Jensen, Thomas Elbenhardt, Richter, Erik A., Wojtaszewski, Jørgen F P, Kiens, Bente & Frøsig, C., 2016, In: Journal of Physiology. 594, 3, p. 745-761 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Regulation of glucose and glycogen metabolism during and after exercise

      Jensen, Thomas Elbenhardt & Richter, Erik A., 2012, In: Journal of Physiology. 590, 5, p. 1069-1076 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    28. Published

      Reply from Lykke Sylow, Lisbeth L. V. Møller, Maximilian Kleinert, Erik A. Richter and Thomas E. Jensen

      Sylow, Lykke, Møller, Lisbeth L V, Kleinert, Maximilian, Richter, Erik A. & Jensen, Thomas Elbenhardt, 2015, In: Journal of Physiology. 593, 9, p. 2239-2240 2 p.

      Research output: Contribution to journal › Comment/debate › Research

    29. Published

      Resistance exercise-induced hypertrophy: A potential role for rapamycin-insensitive mTOR

      Ogasawara, R., Jensen, Thomas Elbenhardt, Goodman, C. A. & Hornberger, T. A., 2019, In: Exercise and Sport Sciences Reviews. 47, 3, p. 188-194

      Research output: Contribution to journal › Review › Research › peer-review

    30. Published

      Role of AMPK in regulation of LC3 lipidation as a marker of autophagy in skeletal muscle

      Fritzen, Andreas Mæchel, Frøsig, C., Jeppesen, J. F., Jensen, Thomas Elbenhardt, Lundsgaard, Anne-Marie, Serup, A. K. L., Schjerling, Peter, Proud, C. G., Richter, Erik A. & Kiens, Bente, 2016, In: Cellular Signalling. 28, 6, p. 663-674 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Role of AMPK in skeletal muscle gene adaptation in relation to exercise

      Jørgensen, S. B., Jensen, Thomas Elbenhardt & Richter, Erik A., 2007, In: Applied Physiology, Nutrition and Metabolism. 32, 5, p. 904-911 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    32. Published

      Skeletal muscle-specific activation of Gq signaling maintains glucose homeostasis

      Bone, D. B. J., Meister, J., Knudsen, Jonas Roland, Dattaroy, D., Cohen, A., Lee, R., Lu, H., Metzger, D., Jensen, Thomas Elbenhardt & Wess, J., 2019, In: Diabetes. 68, 6, p. 1341-1352 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Stretch-stimulated glucose transport in skeletal muscle is regulated by Rac1

      Sylow, Lykke, Møller, L. L. V., Kleinert, Maximilian, Richter, Erik A. & Jensen, Thomas Elbenhardt, 2015, In: Journal of Physiology. 593, 3, p. 645-656 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      TLR2 controls intestinal carcinogen detoxication by CYP1A1

      Do, K. N., Fink, L. N., Jensen, Thomas Elbenhardt, Gautier, L. & Parlesak, Alexandr, 2012, In: P L o S One. 7, 3, 7 p., e32309.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action

      Møller, Lisbeth L V, Ali, Mona Sadek, Davey, J., Raun, Steffen Henning, Andersen, Nicoline Resen, Long, J. Z., Qian, H., Jeppesen, J. F., Henriquez-Olguín, Carlos, Frank, E., Jensen, Thomas Elbenhardt, Højlund, K., Wojtaszewski, Jørgen F P, Nielsen, J., Chiu, T. T., Jedrychowski, M. P., Gregorevic, P., Klip, A., Richter, Erik A. & Sylow, Lykke, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 27, 12 p., e2211041120.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. The Rho-guanine nucleotide exchange factor PDZ-RhoGEF governs susceptibility to diet-induced obesity and type 2 diabetes

      Chang, Y., Pownall, S., Jensen, Thomas Elbenhardt, Mouaaz, S., Foltz, W., Zhou, L., Liadis, N., Woo, M., Hao, Z., Dutt, P., Bilan, P. J., Klip, A., Mak, T. & Stambolic, V., 2015, In: eLife. 4, 24 p., e06011.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      The ULK1/2 and AMPK inhibitor SBI-0206965 blocks AICAR and insulin-stimulated glucose transport

      Knudsen, Jonas Roland, Madsen, A. B., Persson, K. W., Henriquez-Olguín, Carlos, Li, Z. & Jensen, Thomas Elbenhardt, 2020, In: International Journal of Molecular Sciences . 21, 7, 10 p., 2344.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      The emerging roles of nicotinamide adenine dinucleotide phosphate oxidase 2 in skeletal muscle redox signaling and metabolism

      Henriquez-Olguín, Carlos, Boronat, S., Cabello-Verrugio, C., Jaimovich, E., Hidalgo, E. & Jensen, Thomas Elbenhardt, 2019, In: Antioxidants & Redox Signaling. 31, 8, p. 1371-1410 40 p.

      Research output: Contribution to journal › Review › Research › peer-review

    39. Published

      The gut microbiome on a periodized low-protein diet is associated with improved metabolic health

      Li, Z., Rasmussen, Torben Sølbeck, Rasmussen, M. L., Li, J., Henriquez-Olguín, Carlos, Kot, W., Nielsen, Dennis Sandris & Jensen, Thomas Elbenhardt, 2019, In: Frontiers in Microbiology. 10, 10 p., 709.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      The p21-activated kinase 2 (PAK2), but not PAK1, regulates contraction-stimulated skeletal muscle glucose transport

      Møller, Lisbeth L V, Nielsen, I. L., Knudsen, Jonas Roland, Andersen, Nicoline Resen, Jensen, Thomas Elbenhardt, Sylow, Lykke & Richter, Erik A., 2020, In: Physiological Reports. 8, 12, 13 p., e14460.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      The role of NADPH oxidase 2 in regulating IL-15 and PGC-1α gene expressions following a period of high intensity interval training: [The original title and the article is written in Persian!]

      Baghersad Renani, L., Ravasi, A. A., Shabkhiz, F. & Jensen, Thomas Elbenhardt, 2019, In: Iranian Journal of Endocrinology and Metabolism. 20, 5, p. 263-272 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Transparent and cell-guiding cellulose nanofiber 3D printing bioinks

      Radeke, C., Pons, R., Mihajlovic, M., Knudsen, Jonas Roland, Butdayev, S., Kempen, Paul Joseph, Segeritz, C., Andresen, T. L., Pehmøller, C. K., Jensen, Thomas Elbenhardt & Lind, J. U., 2023, In: ACS Applied Materials and Interfaces. 15, 2, p. 2564-2577 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      When less is more: a simple Western blotting amendment allowing data acquisition on human single fibers

      Jensen, Thomas Elbenhardt & Richter, Erik A., 2011, In: Journal of Applied Physiology. 110, 3, p. 583-584 2 p.

      Research output: Contribution to journal › Editorial › Research

    44. Published

      c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action

      Molero, J. C., Jensen, Thomas Elbenhardt, Withers, P. C., Couzens, M., Herzog, H., Thien, C. B. F., Langdon, W. Y., Walder, K., Murphy, M. A., Bowtell, D. D. L., James, D. E. & Cooney, G. J., 2004, In: Journal of Clinical Investigation. 114, 9, p. 1326-1333 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle

      Mori, T., Ato, S., Knudsen, Jonas Roland, Henriquez-Olguín, Carlos, Li, Z., Wakabayashi, K., Suginohara, T., Higashida, K., Tamura, Y., Nakazato, K., Jensen, Thomas Elbenhardt & Ogasawara, R., 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 321, 4, p. E551-E559 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      α-MSH stimulates glucose uptake in mouse muscle and phosphorylates Rab-GTPase-activating protein TBC1D1 independently of AMPK

      Møller, C. L., Kjøbsted, Rasmus, Enriori, P. J., Jensen, Thomas Elbenhardt, Garcia-Rudaz, C., Litwak, S. A., Raun, K., Wojtaszewski, Jørgen F P, Wulff, B. S. & Cowley, M. A., 2016, In: P L o S One. 11, 7, 18 p., e0157027.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      β-actin shows limited mobility and is only required for supraphysiological insulin-stimulated glucose transport in young adult soleus muscle

      Madsen, A. L. B., Knudsen, Jonas Roland, Henriquez-Olguín, Carlos, Angin, Y., Zaal, K. J., Sylow, Lykke, Schjerling, P., Ralston, E. & Jensen, Thomas Elbenhardt, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 315, 1, p. E110-E125 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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