Hannah Grace Caldwell

Hannah Grace Caldwell

PhD Student, Postdoc


  1. 2023
  2. Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent and S-nitrosothiol mediated signal transduction

    Hoiland, R. L., MacLeod, D. B., Stacey, B. S., Caldwell, Hannah Grace, Howe, C. A., Nowak-Flück, D., Carr, J. M. J. R., Tymko, M. M., Coombs, G. B., Patrician, A., Tremblay, J. C., Van Mierlo, M., Gasho, C., Stembridge, M., Sekhon, M. S., Bailey, D. M. & Ainslie, P. N., 12 Apr 2023, (E-pub ahead of print) In: Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Lifelong exposure to high-altitude hypoxia in humans is associated with improved redox homeostasis and structural-functional adaptations of the neurovascular unit

    Stacey, B. S., Hoiland, R. L., Caldwell, Hannah Grace, Howe, C. A., Vermeulen, T., Tymko, M. M., Vizcardo-Galindo, G. A., Bermudez, D., Figueroa-Mujíica, R. J., Gasho, C., Tuaillon, E., Hirtz, C., Lehmann, S., Marchi, N., Tsukamoto, H., Villafuerte, F. C., Ainslie, P. N. & Bailey, D. M., 2023, In: Journal of Physiology. 601, 6, p. 1095-1120 26 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Substrate utilization in the brain and skeletal muscle during environmental and energetic stress in humans

    Caldwell, Hannah Grace, 2023, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen. 250 p.

    Research output: Book/ReportPh.D. thesisResearch

  5. 2022
  6. Nitric oxide contributes to cerebrovascular shear-mediated dilatation but not steady-state cerebrovascular reactivity to carbon dioxide

    Hoiland, R. L., Caldwell, Hannah Grace, Carr, J. M. J. R., Howe, C. A., Stacey, B. S., Dawkins, T., Wakeham, D. J., Tremblay, J. C., Tymko, M. M., Patrician, A., Smith, K. J., Sekhon, M. S., MacLeod, D. B., Green, D. J., Bailey, D. M. & Ainslie, P. N., 15 Mar 2022, In: Journal of Physiology. 600, 6, p. 1385-1403 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Brachial artery responses to acute hypercapnia: The roles of shear stress and adrenergic tone

    Carr, J. M. J. R., Ainslie, P. N., Howe, C. A., Gibbons, T. D., Tymko, M. M., Steele, A. R., Hoiland, R. L., Vizcardo-Galindo, G. A., Patrician, A., Brown, C. V., Caldwell, Hannah Grace & Tremblay, J. C., 2022, In: Experimental Physiology. 107, 12, p. 1440-1453 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Gastric inhibitory polypeptide as the new candidate for the interaction of skeletal muscle blood flow and glucose disposal

    Tamariz-Ellemann, Andrea, Caldwell, Hannah Grace & Gliemann, Lasse, 2022, In: Journal of Physiology. 600, 7, p. 1593-1595 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. High prevalence of patent foramen ovale in recreational to elite breath hold divers

    Kelly, T., Patrician, A., Bryant-Ekstrand, M., Brown, C., Gasho, C., Caldwell, Hannah Grace, Lord, R. N., Dawkins, T., Drane, A., Stembridge, M., Dragun, T., Barak, O., Spajić, B., Drviš, I., Duke, J. W., Foster, G. E., Ainslie, P. N., Dujić, Ž. & Lovering, A. T., 2022, In: Journal of Science and Medicine in Sport. 25, 7, p. 553-556 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    How do we kNOw the individual contribution of eNOS and nNOS for cerebral blood flow regulation?

    Rocha, Marcos Paulo, Caldwell, Hannah Grace & Gliemann, Lasse, 2022, In: Journal of Physiology. 600, 1, p. 3-4 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Trans-cerebral HCO3 and PCO2 exchange during acute respiratory acidosis and exercise-induced metabolic acidosis in humans

    Caldwell, Hannah Grace, Hoiland, R. L., Smith, K. J., Brassard, P., Bain, A. R., Tymko, M. M., Howe, C. A., Carr, J. M. J. R., Stacey, B. S., Bailey, D. M., Drapeau, A., Sekhon, M. S., MacLeod, D. B. & Ainslie, P. N., 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 4, p. 559-571 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2021
  13. Acid–base balance and cerebrovascular regulation

    Caldwell, Hannah Grace, Carr, J. M. J. R., Minhas, J. S., Swenson, E. R. & Ainslie, P. N., 2021, In: Journal of Physiology. 599, 24, p. 5337-5359 23 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Alterations in arterial CO2 rather than pH affect the kinetics of neurovascular coupling in humans

    Caldwell, Hannah Grace, Howe, C. A., Hoiland, R. L., Carr, J. M. J. R., Chalifoux, C. J., Brown, C. V., Patrician, A., Tremblay, J. C., Panerai, R. B., Robinson, T. G., Minhas, J. S. & Ainslie, P. N., 2021, In: Journal of Physiology. 599, 15, p. 3663-3676 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Arterial carbon dioxide and bicarbonate rather than pH regulate cerebral blood flow in the setting of acute experimental metabolic alkalosis

    Caldwell, Hannah Grace, Howe, C. A., Chalifoux, C. J., Hoiland, R. L., Carr, J. M. J. R., Brown, C. V., Patrician, A., Tremblay, J. C., Panerai, R. B., Robinson, T. G., Minhas, J. S. & Ainslie, P. N., 2021, In: Journal of Physiology. 599, 5, p. 1439-1457 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Blunted cerebrovascular CO2 reactivity to satisfy the hungry heat stressed brain

    Caldwell, Hannah Grace, 2021, In: Journal of Physiology. 599, 10, p. 2513-2515 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  17. Case studies in physiology: Breath-hold diving beyond 100 meters—cardiopulmonary responses in world-champion divers

    Patrician, A., Gasho, C., Spajić, B., Caldwell, Hannah Grace, Baković-Kramaric, D., Barak, O., Drviš, I., Dujić, Ž. & Ainslie, P. N., 2021, In: Journal of Applied Physiology. 130, 5, p. 1345-1350 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Cerebral blood flow, cerebrovascular reactivity and their influence on ventilatory sensitivity

    Carr, J. M. J. R., Caldwell, Hannah Grace & Ainslie, P. N., 2021, In: Experimental Physiology. 106, 7, p. 1425-1448 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Hourly staircase sprinting exercise “snacks” improve femoral artery shear patterns but not flow-mediated dilation or cerebrovascular regulation: A pilot study

    Caldwell, Hannah Grace, Coombs, G. B., Rafiei, H., Ainslie, P. N. & Little, J. P., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 5, p. 521-529 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Losing the dogmatic view of cerebral autoregulation

    Brassard, P., Labrecque, L., Smirl, J. D., Tymko, M. M., Caldwell, Hannah Grace, Hoiland, R. L., Lucas, S. J. E., Denault, A. Y., Couture, E. J. & Ainslie, P. N., 2021, In: Physiological Reports. 9, 15, 11 p., e14982.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Regulation of cerebral blood flow by arterial PCO2 independent of metabolic acidosis at 5050 m

    Caldwell, Hannah Grace, Smith, K. J., Lewis, N. C. S., Hoiland, R. L., Willie, C. K., Lucas, S. J. E., Stembridge, M., Burgess, K. R., MacLeod, D. B. & Ainslie, P. N., 2021, In: Journal of Physiology. 599, 14

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Short-term ketone monoester supplementation improves cerebral blood flow and cognition in obesity: A randomized cross-over trial

    Walsh, J. J., Caldwell, Hannah Grace, Neudorf, H., Ainslie, P. N. & Little, J. P., 2021, In: Journal of Physiology. 599, 21, p. 4763-4778 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Temporal changes in pulmonary gas exchange efficiency when breath-hold diving below residual volume

    Patrician, A., Spajić, B., Gasho, C., Caldwell, Hannah Grace, Dawkins, T., Stembridge, M., Lovering, A. T., Coombs, G. B., Howe, C. A., Barak, O., Drviš, I., Dujić, Ž. & Ainslie, P. N., 2021, In: Experimental Physiology. 106, 4, p. 1120-1133 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. The stability of cerebrovascular CO2 reactivity following attainment of physiological steady-state

    Carr, J. M. J. R., Caldwell, Hannah Grace, Carter, H., Smith, K., Tymko, M. M., Green, D. J., Ainslie, P. N. & Hoiland, R. L., 2021, In: Experimental Physiology. 106, 12, p. 2542-2555 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2020
  26. Alterations in resting cerebrovascular regulation do not affect reactivity to hypoxia, hyperoxia or neurovascular coupling following a SCUBA dive

    Caldwell, Hannah Grace, Hoiland, R. L., Barak, O. F., Mijacika, T., Burma, J. S., Dujić, Ž. & Ainslie, P. N., 2020, In: Experimental Physiology. 105, 9, p. 1540-1549 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Cerebrovascular reactivity to carbon dioxide is not influenced by variability in the ventilatory sensitivity to carbon dioxide

    Howe, C. A., Caldwell, Hannah Grace, Carr, J., Nowak-Flück, D., Ainslie, P. N. & Hoiland, R. L., 2020, In: Experimental Physiology. 105, 5, p. 904-915 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Evidence for temperature-mediated regional increases in cerebral blood flow during exercise

    Caldwell, Hannah Grace, Coombs, G. B., Howe, C. A., Hoiland, R. L., Patrician, A., Lucas, S. J. E. & Ainslie, P. N., 2020, In: Journal of Physiology. 598, 8, p. 1459-1473 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Global REACH 2018: The influence of acute and chronic hypoxia on cerebral haemodynamics and related functional outcomes during cold and heat stress

    Gibbons, T. D., Tymko, M. M., Thomas, K. N., Wilson, L. C., Stembridge, M., Caldwell, Hannah Grace, Howe, C. A., Hoiland, R. L., Akerman, A. P., Dawkins, T. G., Patrician, A., Coombs, G. B., Gasho, C., Stacey, B. S., Ainslie, P. N. & Cotter, J. D., 2020, In: Journal of Physiology. 598, 2, p. 265-284 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Internal carotid and brachial artery shear-dependent vasodilator function in young healthy humans

    Carr, J. M. J. R., Hoiland, R. L., Caldwell, Hannah Grace, Coombs, G. B., Howe, C. A., Tremblay, J. C., Green, D. J. & Ainslie, P. N., 2020, In: Journal of Physiology. 598, 23, p. 5333-5350 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Nitric oxide is fundamental to neurovascular coupling in humans

    Hoiland, R. L., Caldwell, Hannah Grace, Howe, C. A., Nowak-Flück, D., Stacey, B. S., Bailey, D. M., Paton, J. F. R., Green, D. J., Sekhon, M. S., Macleod, D. B. & Ainslie, P. N., 2020, In: Journal of Physiology. 598, 21, p. 4927-4939 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2019
  33. A ketone monoester drink reduces the glycemic response to an oral glucose challenge in individuals with obesity: A randomized trial

    Myette-Côté, É., Caldwell, Hannah Grace, Ainslie, P. N., Clarke, K. & Little, J. P., 2019, In: American Journal of Clinical Nutrition. 110, 6, p. 1491-1501 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Cerebrovascular function is preserved during mild hyperthermia in cervical spinal cord injury

    Coombs, G. B., Vucina, D., Caldwell, Hannah Grace, Barak, O. F., Mijacika, T., Lee, A. H. X., Sarafis, Z. K., Squair, J. W., Krassioukov, A. V., Phillips, A. A., Dujic, Z. & Ainslie, P. N., 2019, In: Spinal Cord. 57, 11, p. 979-984 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. The effect of an expiratory resistance mask with dead space on sleep, acute mountain sickness, cognition, and ventilatory acclimatization in normobaric hypoxia

    Patrician, A., Tymko, M. M., Caldwell, Hannah Grace, Howe, C. A., Coombs, G. B., Stone, R., Hamilton, A., Hoiland, R. L. & Ainslie, P. N., 2019, In: High Altitude Medicine and Biology. 20, 1, p. 61-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2018
  37. Emerging views of how changes in blood pressure influence cerebral blood flow

    Caldwell, Hannah Grace, 2018, In: Journal of Physiology. 596, 19, p. 4565-4567 3 p.

    Research output: Contribution to journalComment/debateResearch

  38. Severity-dependent influence of isocapnic hypoxia on reaction time is independent of neurovascular coupling

    Caldwell, Hannah Grace, Coombs, G. B., Tymko, M. M., Nowak-Flück, D. & Ainslie, P. N., 2018, In: Physiology and Behavior. 188, p. 262-269 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2017
  40. Stability in neurovascular function at 3800 m

    Caldwell, Hannah Grace, Ainslie, P. N., Ellis, L. A., Phillips, A. A. & Flück, D., 2017, In: Physiology and Behavior. 182, p. 62-68 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 232630465