Jørgen Wojtaszewski

Jørgen Wojtaszewski

Professor

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    ORCID: 0000-0001-8185-3408

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    1. Published

      Lipid induced insulin resistance affects women less than men and is not accompanied by inflammation or impaired proximal insulin signaling

      Høeg, L. D., Sjøberg, K. A., Jeppesen, J., Jensen, Thomas Elbenhardt, Frøsig, C., Birk, Jesper Bratz, Bisiani, B., Hiscock, N., Pilegaard, Henriette, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2011, In: Diabetes. 60, 1, p. 64-73 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Lack of AMPKalpha2 enhances pyruvate dehydrogenase activity during exercise

      Klein, D. K., Pilegaard, Henriette, Treebak, Jonas Thue, Jensen, Thomas Elbenhardt, Viollet, B., Schjerling, Peter & Wojtaszewski, Jørgen F P, 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 5, p. E1242-E1249 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      LKB1 regulates lipid oxidation during exercise independently of AMPK

      Jeppesen, J. F., Maarbjerg, S. J., Jordy, A. B., Fritzen, Andreas Mæchel, Pehmøller, C., Sylow, Lykke, Serup, A. K. L., Jessen, N., Thorsen, K., Prats Gavalda, Clara, Qvortrup, Klaus, Dyck, J. R. B., Hunter, R. W., Sakamoto, Kei, Thomson, D. M., Schjerling, Peter, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2013, In: Diabetes. 62, 5, p. 1490-1499 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside- but not contraction-induced glucose uptake in skeletal muscle

      Jørgensen, S. B., Viollet, B., Andreelli, F., Frøsig, C., Birk, Jesper Bratz, Schjerling, P., Vaulont, S., Richter, Erik A. & Wojtaszewski, Jørgen F P, 2004, In: Journal of Biological Chemistry. 279, 2, p. 1070-1079 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Kinetics of lactate transport in sarcolemmal giant vesicles obtained from human skeletal muscle

      Juel, C., Kristiansen, S., Pilegaard, Henriette, Wojtaszewski, Jørgen F P & Richter, Erik A., 1994, In: Journal of Applied Physiology. 76, 3, p. 1031-1036 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Kinase activity determination of specific AMPK complexes/heterotrimers in the skeletal muscle

      Birk, Jesper Bratz & Wojtaszewski, Jørgen F P, 2018, AMPK: Methods and Protecols. Neumann, D. & Viollet, B. (eds.). New York: Humana Press, p. 215-228 14 p. (Methods in Molecular Biology; No. 1732).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    7. Published

      Ketone body infusion abrogates growth hormone-induced lipolysis and insulin resistance

      Høgild, M. L., Hjelholt, A. J., Hansen, J., Pedersen, Steen, Møller, N., Wojtaszewski, Jørgen F P, Johannsen, M., Jessen, N. & Lunde Jørgensen, J. O., 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 3, p. 653-664 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Isoform-specific and exercise intensity-dependent activation of 5'-AMP-activated protein kinase in human skeletal muscle

      Wojtaszewski, Jørgen F P, Nielsen, P. K., Hansen, B. F., Richter, Erik A. & Kiens, Bente, 2000, In: Journal of Physiology. 528, 1, p. 221-226 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Invited review: Effect of acute exercise on insulin signaling and action in humans

      Wojtaszewski, Jørgen F P, Nielsen, J. N. & Richter, Erik A., 2002, In: Journal of Applied Physiology. 93, 1, p. 384-392 9 p.

      Research output: Contribution to journal › Review › Research

    10. Published

      Interleukin-6 release from human skeletal muscle during exercise: relation to AMPK activity

      MacDonald, C. S., Wojtaszewski, Jørgen F P, Klarlund Pedersen, B., Kiens, Bente & Richter, Erik A., 2003, In: Journal of Applied Physiology. 95, 6, p. 2273-2277

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Interleukin-6 modifies mRNA expression in mouse skeletal muscle

      Hassing, H. A., Wojtaszewski, Jørgen F P, Jakobsen, A. H., Kiilerich, K., Hidalgo, J. & Pilegaard, Henriette, 2011, In: Acta Physiologica. 202, 2, p. 165-173 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Intact regulation of the AMPK signaling network in response to exercise and insulin in skeletal muscle of male patients with type 2 diabetes: Illumination of AMPK activation in recovery from exercise

      Kjøbsted, Rasmus, Pedersen, A. J. T., Hingst, J. R., Sabaratnam, R., Birk, Jesper Bratz, Kristensen, Jonas Møller, Højlund, K. & Wojtaszewski, Jørgen F P, 2016, In: Diabetes. 65, 5, p. 1219-1230 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Intact regulation of muscle expression and circulating levels of myokines in response to exercise in patients with type 2 diabetes

      Sabaratnam, R., Pedersen, A. J. T., Kristensen, Jonas Møller, Handberg, A., Wojtaszewski, Jørgen F P & Højlund, K., Jun 2018, In: Physiological Reports. 6, 12, 12 p., e13723.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Intact initiation of autophagy and mitochondrial fission by acute exercise in skeletal muscle of patientswith type 2 diabetes

      Kruse Sørensen, R., Pedersen, A. J. T., Kristensen, Jonas Møller, Petersson, S. J., Wojtaszewski, Jørgen F P & Højlund, K., 2017, In: Clinical Science. 131, 1, p. 37-47 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Insulin-induced membrane permeability to glucose in human muscles at rest and following exercise

      McConell, G. K., Sjøberg, K. A., Ceutz, F., Gliemann, Lasse, Nyberg, M. P., Hellsten, Ylva, Frøsig, C., Kiens, Bente, Wojtaszewski, Jørgen F P & Richter, Erik A., 2020, In: Journal of Physiology. 598, 2, p. 303-315 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Insulin signalling: effects of prior exercise

      Wojtaszewski, Jørgen F P, Jørgensen, S. B., Frøsig, C., MacDonald, C. S., Birk, J. B. & Richter, Erik A., 2003, In: Acta Physiologica (Print Edition). 178, 4, p. 321-328

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Insulin signaling in human skeletal muscle: time course and effect of exercise

      Wojtaszewski, Jørgen F P, Hansen, B. F., Kiens, Bente & Richter, Erik A., 1997, In: Diabetes. 46, p. 1775-1781

      Research output: Contribution to journal › Journal article › Research

    18. Published

      Insulin signaling and insulin sensitivity after exercise in human skeletal muscle

      Wojtaszewski, Jørgen F P, Hansen, B. F., Gade, J., Kiens, Bente, Markuns, J. F., Goodyear, L. J. & Richter, Erik A., 2000, In: Diabetes. 49, 3, p. 325-331 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Insulin sensitization following a single exercise bout is uncoupled to glycogen in human skeletal muscle: A meta-analysis of 13 single-center human studies

      Hingst, J. R., Onslev, Johan Dejgaard, Holm, S., Kjøbsted, Rasmus, Frøsig, C., Kido, K., Steenberg, D. E., Larsen, Magnus Romme, Kristensen, Jonas Møller, Carl, Christian Strini, Sjøberg, K., Thong, F. S. L., Derave, W., Pehmøller, C., Brandt, N., McConell, G., Jensen, J., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2022, In: Diabetes. 71, 11, p. 2237-2250 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle

      Vendelbo, M., Clasen, B. F. F., Treebak, Jonas Thue, Møller, L., Krusenstjerna-Hafstrøm, T., Madsen, M., Nielsen, Thomas Svava, Stødkilde-Jørgensen, H., Pedersen, S. B., Jørgensen, J. O. L., Goodyear, L. J., Wojtaszewski, Jørgen F P, Møller, N. & Jessen, N., 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 302, 2, p. E190-E200 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Insulin receptor substrate-2 is not necessary for insulin- and exercise-stimulated glucose transport in skeletal muscle

      Higaki, Y., Wojtaszewski, Jørgen F P, Hirshman, M. F., Withers, D. J., Towery, H., White, M. F. & Goodyear, L. J., 1999, In: Journal of Biological Chemistry. 274, 30, p. 20791-20795 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Insulin and exercise decrease glycogen synthase kinase-3 activity by different mechanisms in rat skeletal muscle

      Markuns, J. F., Wojtaszewski, Jørgen F P & Goodyear, L. J., 1999, In: Journal of Biological Chemistry. 274, 35, p. 24896-24900 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Inhibition of lipolysis stimulates peripheral glucose uptake but has no effect on endogenous glucose production in HIV lipodystrophy

      Lindegaard, Birgitte, Frøsig, C., Petersen, A. M. W., Plomgaard, Peter Stendahl, Ditlevsen, Susanne, Mittendorfer, B., van Hall, Gerrit, Wojtaszewski, Jørgen F P & Pedersen, Bente Klarlund, 2007, In: Diabetes. 56, 8, p. 2070-2077 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

      Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, Hellsten, Ylva & Wojtaszewski, Jørgen F P, 2020, In: Molecular Metabolism. 40, 17 p., 101028.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Increased skeletal muscle capillarization enhances insulin sensitivity

      Åkerström, T., Laub, L., Vedel, K., Brand, C. L., Pedersen, Bente Klarlund, Kaufmann Lindqvist, A., Wojtaszewski, Jørgen F P & Hellsten, Ylva, 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 307, 12, p. E1105-E1116 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes

      Højlund, K., Stæhr, P., Falck Hansen, B., Green, K. A., Hardie, D. G., Richter, Erik A., Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2003, In: Diabetes. 52, 6, p. 1393-1402

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Increased atypical PKC activity in endurance-trained human skeletal muscle

      Nielsen, J. N., Frøsig, C., Sajan, M. P., Miura, A., Standaert, M. L., Graham, D. A., Wojtaszewski, Jørgen F P, Farese, R. V. & Richter, Erik A., 2003, In: Biochemical and Biophysical Research Communications. 312, 4, p. 1147-1153

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Impairments in site-specific AS160 phosphorylation and effects of exercise training

      Consitt, L. A., Van Meter, J., Newton, C. A., Collier, D. N., Dar, M. S., Wojtaszewski, Jørgen F P, Treebak, Jonas Thue, Tanner, C. J. & Houmard, J. A., 2013, In: Diabetes. 62, 10, p. 3437-3447 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Impaired leptin gene expression and release in cultured preadipocytes isolated from individuals born with low birth weight

      Schultz, N. S., Broholm, C., Gillberg, L., Mortensen, B., Jørgensen, S. W., Schultz, H. S., Schéele, Camilla Charlotte Nielsen, Wojtaszewski, Jørgen F P, Pedersen, Bente Klarlund & Vaag, Allan, 2014, In: Diabetes. 63, 1, p. 111-121 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment

      Højlund, K., Glintborg, D., Andersen, Nicoline Resen, Birk, Jesper Bratz, Treebak, Jonas Thue, Frøsig, C., Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2008, In: Diabetes. 57, 2, p. 357-366 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training

      Vind, B. F., Pehmøller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Hey-Mogensen, M., Beck-Nielsen, H., Zierath, J. R., Wojtaszewski, Jørgen F P & Højlund, K., 2011, In: Diabetologia. 54, 1, p. 157-167 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Impaired insulin activation and dephosphorylation of glycogen synthase in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment

      Glintborg, D., Højlund, K., Andersen, Nicoline Resen, Hansen, B. F., Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 9, p. 3618-3626 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Impaired Insulin-Mediated Phosphorylation of Skeletal Muscle TBC1D4 at Multiple Sites in Type 2 Diabetes. Effect of Endurance Training on TBC1D4 Protein and Phosphorylation

      Vind, B. F., Pehmoller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Hey-Mogensen, M., Beck-Nielsen, H., Wojtaszewski, Jørgen F P & Hojlund, K., 2009, In: Diabetes.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle

      Ribel-Madsen, R., Poulsen, P., Holmkvist, J., Mortensen, B., Grarup, Niels, Friedrichsen, M., Jørgensen, T., Lauritzen, T., Wojtaszewski, Jørgen F P, Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 2010, In: Diabetes. 59, 4, p. 1108-1112 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Impact of genetic versus environmental factors on the control of muscle glycogen synthase activation in twins

      Poulsen, P., Wojtaszewski, Jørgen F P, Petersen, I., Christensen, K., Richter, Erik A., Beck-Nielsen, H. & Vaag, A., 2005, In: Diabetes. 54, 5, p. 1289-1296 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Illumination of the endogenous insulin-regulated TBC1D4 interactome in human skeletal muscle

      Larsen, Jeppe Kjærgaard, Larsen, Magnus Romme, Birk, Jesper Bratz, Steenberg, D. E., Hingst, J. R., Højlund, K., Chadt, A., Al-Hasani, H., Deshmukh, Atul Shahaji, Wojtaszewski, Jørgen F P & Kjøbsted, Rasmus, 2022, In: Diabetes. 71, 5, p. 906-920

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Identifying the heterotrimeric complex stoichiometry of AMPK in skeletal muscle by immunoprecipitation

      Birk, Jesper Bratz & Wojtaszewski, Jørgen F P, 2018, AMPK: Methods and Protecols. Neumann, D. & Viollet, B. (eds.). New York: Humana Press, p. 203-213 11 p. (Methods in Molecular Biology; No. 1732).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    38. Published

      Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle

      Treebak, Jonas Thue, Taylor, E. B., Witczak, C. A., An, D., Toyoda, T., Koh, H., Xie, J., Feener, E. P., Wojtaszewski, Jørgen F P, Hirshman, M. F. & Goodyear, L. J., 2010, In: American Journal of Physiology: Cell Physiology. 298, 2, p. C377-C385 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      IL-6 regulates exercise and training-induced adaptations in subcutaneous adipose tissue in mice

      Brandt, C., Jakobsen, A. H., Hassing, H. A., Olesen, Jes, Iversen, N., Kristensen, Jonas Møller, Hojman, P., Wojtaszewski, Jørgen F P, Hidalgo, J. & Pilegaard, Henriette, 2012, In: Acta Physiologica (Print). 205, 2, p. 224-235 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Hypoxia and contractions do not utilize the same signaling mechanism in stimulating skeletal muscle glucose transport

      Wojtaszewski, Jørgen F P, Lynge, J., Derave, W. & Richter, Erik A., 1998, In: BBA General Subjects. 1380, p. 396-404 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Hyperphosphorylation and low protein content of muscle glycogen synthase contribute to insulin resistance in polycystic ovary syndrome: effects of pioglitazone treatment

      Hojlund, K., Glintborg, D., Andersen, N. R., Birk, Jesper Bratz, Treebak, Jonas Thue, Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2007, In: Diabetologia.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Hyperglycaemia normalises insulin action on glucose metabolism but not the impaired activation of AKT and glycogen synthase in the skeletal muscle of patients with type 2 diabetes

      Vind, B. F., Birk, Jesper Bratz, Vienberg, S. G., Andersen, B., Beck-Nielsen, H., Wojtaszewski, Jørgen F P & Højlund, K., 2012, In: Diabetologia. 55, 5, p. 1435-1445 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Human muscle fibre type-specific regulation of AMPK and downstream targets by exercise

      Kristensen, D. E., Albers, P. H., Prats, C., Baba, O., Birk, Jesper Bratz & Wojtaszewski, Jørgen F P, 2015, In: Journal of Physiology. 593, 8, p. 2053-2069 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Human muscle fiber type-specific insulin signaling: Impact of obesity and type 2 diabetes

      Albers, P. H., Pedersen, A. J. T., Birk, Jesper Bratz, Kristensen, D. E., Vind, B. F., Baba, O., Nøhr, J., Højlund, K. & Wojtaszewski, Jørgen F P, 2015, In: Diabetes. 64, 2, p. 485-497 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Homage to August Krogh celebrating the 90th anniversary of his Nobel prize in Physiology or Medicine

      Larsen, Erik Hviid, Hellsten, Ylva & Wojtaszewski, Jørgen F P, 2011, In: Acta Physiologica (Print). 202, 3, p. 211-212 2 p.

      Research output: Contribution to journal › Editorial › Research › peer-review

    46. Published

      Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise

      Roepstorff, C., Thiele, M., Hillig, T., Pilegaard, Henriette, Richter, Erik A., Wojtaszewski, Jørgen F P & Kiens, Bente, 2006, In: Journal of Physiology. 574, 1, p. 125-138 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Higher intramuscular triacylglycerol in women does not impair insulin sensitivity and proximal insulin signaling

      Høeg, L., Roepstorff, C., Thiele, M., Richter, Erik A., Wojtaszewski, Jørgen F P & Kiens, Bente, 2009, In: Journal of Applied Physiology. 107, p. 824-831 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Hexokinase 2, glycogen synthase and phosphorylase play a key role in muscle glycogen supercompensation

      Irimia, J. M., Rovira, J., Nielsen, J. N., Guerrero, M., Wojtaszewski, Jørgen F P & Cussó, R., 2012, In: P L o S One. 7, 7, p. e42453 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Greater phosphorylation of AMPK and multiple AMPK substrates in the skeletal muscle of 24-month-old calorie restricted compared to ad libitum fed male rats

      Zheng, A., Kwak, S. E., Birk, Jesper Bratz, Arias, E. B., Thorley, D., Wojtaszewski, Jørgen F P & Cartee, G. D., 2023, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 78, 2, p. 177-185 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle

      Wojtaszewski, Jørgen F P, Jørgensen, S. B., Hellsten, Ylva, Hardie, D. G. & Richter, Erik A., 2002, In: Diabetes. 51, 2, p. 284-292

      Research output: Contribution to journal › Journal article › Research › peer-review

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