Bioaccessibility assessment of arsenic and cadmium in polished and unpolished rice: Comparison of three in vitro methods
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Bioaccessibility assessment of arsenic and cadmium in polished and unpolished rice : Comparison of three in vitro methods. / Ma, Jingnan; Yin, Naiyi; Wang, Pengfei; Cai, Xiaolin; Geng, Ziqi; Fan, Chuanfang; Cui, Yanshan; Sjödin, Anders.
In: Food Research International, Vol. 177, 113853, 2024.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Bioaccessibility assessment of arsenic and cadmium in polished and unpolished rice
T2 - Comparison of three in vitro methods
AU - Ma, Jingnan
AU - Yin, Naiyi
AU - Wang, Pengfei
AU - Cai, Xiaolin
AU - Geng, Ziqi
AU - Fan, Chuanfang
AU - Cui, Yanshan
AU - Sjödin, Anders
N1 - Publisher Copyright: © 2023 Elsevier Ltd
PY - 2024
Y1 - 2024
N2 - INFOGEST is a standardized in vitro digestion method suitable for foods, but rarely used to study the bioaccessibility of heavy metals in food. This study aimed to explore the differences between INFOGEST and the extensively used Physiologically Based Extraction Test (PBET) and Unified Bioaccessibility Research Group of Europe Method (UBM) methods for determining the bioaccessibility of As and Cd in rice. Intestinal As (79.3 ± 8.5 %, 75.8 ± 12.7 %, and 72.3 ± 12.2 % for INFOGEST, PBET, and UBM, respectively) and Cd (47.0 ± 6.4 %, 40.7 ± 13.8 %, and 38.1 ± 15.7 % for INFOGEST, PBET, and UBM, respectively) bioaccessibilities in the rice samples determined by the three methods were generally similar (p > 0.1, except for As bioaccessibility between INFOGEST and UBM). Furthermore, PBET was significantly correlated with INFOGEST for As bioaccessibility (R2 = 0.416) and with UBM for Cd bioaccessibility (R2 = 0.879). Additionally, PBET indicated that the bioaccessibilities of As and Cd in the polished rice were 17.0 % and 19.8 % higher, respectively, than that in the unpolished rice. This study highlights the influence of in vitro methods and rice matrices on heavy metal bioaccessibility values, necessitating a more accurate assessment of health risks associated with rice consumption.
AB - INFOGEST is a standardized in vitro digestion method suitable for foods, but rarely used to study the bioaccessibility of heavy metals in food. This study aimed to explore the differences between INFOGEST and the extensively used Physiologically Based Extraction Test (PBET) and Unified Bioaccessibility Research Group of Europe Method (UBM) methods for determining the bioaccessibility of As and Cd in rice. Intestinal As (79.3 ± 8.5 %, 75.8 ± 12.7 %, and 72.3 ± 12.2 % for INFOGEST, PBET, and UBM, respectively) and Cd (47.0 ± 6.4 %, 40.7 ± 13.8 %, and 38.1 ± 15.7 % for INFOGEST, PBET, and UBM, respectively) bioaccessibilities in the rice samples determined by the three methods were generally similar (p > 0.1, except for As bioaccessibility between INFOGEST and UBM). Furthermore, PBET was significantly correlated with INFOGEST for As bioaccessibility (R2 = 0.416) and with UBM for Cd bioaccessibility (R2 = 0.879). Additionally, PBET indicated that the bioaccessibilities of As and Cd in the polished rice were 17.0 % and 19.8 % higher, respectively, than that in the unpolished rice. This study highlights the influence of in vitro methods and rice matrices on heavy metal bioaccessibility values, necessitating a more accurate assessment of health risks associated with rice consumption.
KW - Brown rice
KW - Heavy metals
KW - INFOGEST
KW - PBET
KW - Rice matrices
KW - UBM
KW - White rice
U2 - 10.1016/j.foodres.2023.113853
DO - 10.1016/j.foodres.2023.113853
M3 - Journal article
C2 - 38225128
AN - SCOPUS:85180371823
VL - 177
JO - Food Research International
JF - Food Research International
SN - 0963-9969
M1 - 113853
ER -
ID: 387146502