The effectiveness of a standardized rose hip powder, containing seeds and Shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity
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The effectiveness of a standardized rose hip powder, containing seeds and Shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity . / Phetcharat, L; Wongsuphasawat, K; Winther, Kaj.
In: Clinical Interventions in Aging (Print), Vol. 10, 2015, p. 1849-1856.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - The effectiveness of a standardized rose hip powder, containing seeds and Shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity
AU - Phetcharat, L
AU - Wongsuphasawat, K
AU - Winther, Kaj
N1 - CURIS 2015 NEXS 382
PY - 2015
Y1 - 2015
N2 - Objective: To evaluate the effects of a rose hip powder (Hyben Vital®) made from seeds and shells on cell senescence, skin wrinkling, and aging.Methods: A total of 34 healthy subjects, aged 35–65 years, with wrinkles on the face (crow’s-feet) were subjected to a randomized and double-blinded clinical study of the effects of the rose hip powder, as compared to astaxanthin, a well-known remedy against wrinkles. During the 8-week study, half of the participants ingested the standardized rose hip product, while the other half ingested astaxanthin. Objective measurements of facial wrinkles, skin moisture, and elasticity were made by using Visioscan, Corneometer, and Cutometer at the beginning of the study, after 4 weeks, and after 8 weeks. Evaluation of participant satisfaction of both supplements was assessed using questionnaires. In addition, the effect of the rose hip preparation on cell longevity was measured in terms of leakage of hemoglobin through red cell membranes (hemolytic index) in blood samples kept in a blood bank for 5 weeks. Significance of all values was attained with P#0.05.Results: In the double-blinded study, the rose hip group showed statistically significant improvements in crow’s-feet wrinkles (P,0.05), skin moisture (P,0.05), and elasticity (P,0.05) after 8 weeks of treatment. A similar improvement was observed for astaxanthin, with P-values 0.05, 0.001, and 0.05. Likewise, both groups expressed equal satisfaction with the results obtained in their self-assessment. The rose hip powder further resulted in increased cell longevity of erythrocyte cells during storage for 5 weeks in a blood bank.Conclusion: Results suggest that intake of the standardized rose hip powder (Hyben Vital®) improves aging-induced skin conditions. The apparent stabilizing effects of the rose hip product on cell membranes of stored erythrocyte cells observed in this study may contribute to improve the cell longevity and obstructing skin aging.Keywords: rose hip seed and shell powder, cell longevity, wrinkles, aging skin, moisture, elasticity
AB - Objective: To evaluate the effects of a rose hip powder (Hyben Vital®) made from seeds and shells on cell senescence, skin wrinkling, and aging.Methods: A total of 34 healthy subjects, aged 35–65 years, with wrinkles on the face (crow’s-feet) were subjected to a randomized and double-blinded clinical study of the effects of the rose hip powder, as compared to astaxanthin, a well-known remedy against wrinkles. During the 8-week study, half of the participants ingested the standardized rose hip product, while the other half ingested astaxanthin. Objective measurements of facial wrinkles, skin moisture, and elasticity were made by using Visioscan, Corneometer, and Cutometer at the beginning of the study, after 4 weeks, and after 8 weeks. Evaluation of participant satisfaction of both supplements was assessed using questionnaires. In addition, the effect of the rose hip preparation on cell longevity was measured in terms of leakage of hemoglobin through red cell membranes (hemolytic index) in blood samples kept in a blood bank for 5 weeks. Significance of all values was attained with P#0.05.Results: In the double-blinded study, the rose hip group showed statistically significant improvements in crow’s-feet wrinkles (P,0.05), skin moisture (P,0.05), and elasticity (P,0.05) after 8 weeks of treatment. A similar improvement was observed for astaxanthin, with P-values 0.05, 0.001, and 0.05. Likewise, both groups expressed equal satisfaction with the results obtained in their self-assessment. The rose hip powder further resulted in increased cell longevity of erythrocyte cells during storage for 5 weeks in a blood bank.Conclusion: Results suggest that intake of the standardized rose hip powder (Hyben Vital®) improves aging-induced skin conditions. The apparent stabilizing effects of the rose hip product on cell membranes of stored erythrocyte cells observed in this study may contribute to improve the cell longevity and obstructing skin aging.Keywords: rose hip seed and shell powder, cell longevity, wrinkles, aging skin, moisture, elasticity
U2 - 10.2147/CIA.S90092
DO - 10.2147/CIA.S90092
M3 - Journal article
C2 - 26604725
VL - 10
SP - 1849
EP - 1856
JO - Clinical Interventions in Aging (Online)
JF - Clinical Interventions in Aging (Online)
SN - 1178-1998
ER -
ID: 148479682