Influence of breathing on variation in cardiac stroke volume at the onset of cycling
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Influence of breathing on variation in cardiac stroke volume at the onset of cycling. / Sejersen, Casper; Rocha, Marcos Paulo; Van Lieshout, Johannes J.; Secher, Niels H.
In: European Journal of Applied Physiology, Vol. 121, No. 11, 2021, p. 3061-3067.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Influence of breathing on variation in cardiac stroke volume at the onset of cycling
AU - Sejersen, Casper
AU - Rocha, Marcos Paulo
AU - Van Lieshout, Johannes J.
AU - Secher, Niels H.
N1 - Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2021
Y1 - 2021
N2 - Purpose: During cycling, the variation in cardiac stroke volume (SVV) is similar to that at rest. However, SVV may be influenced by ventilation at the start of cycling, e.g., by a Valsalva-like maneuver used to stabilize the body. This study evaluated the influence of ventilation on SV during initiation of cycling. Methods: Ten healthy recreationally physical active males (mean ± SD: age 26 ± 3 years, height 184 ± 9 cm, weight 85 ± 9 kg) cycled on an ergometer for four 30 s intervals at submaximal workloads while synchronizing ventilatory and cardiovascular variables derived from gas exchange and arterial pulse contour analysis, respectively. Results: At exercise onset, cardiac output increased by an instantaneous rise in heart rate and SV (P < 0.05). In contrast, blood pressure increased only after 15 s (P < 0.05), reflected in a decline in total peripheral resistance from exercise onset (P < 0.05). SVV was similar at rest (20 ± 6%) and during exercise (21 ± 5%) except for the first 5 s of exercise when a ~ 2.5-fold elevation (47 ± 6%; P < 0.05) was correlated to variation in respiratory frequency (= 0.71, P = 0.02) and tidal volume (R = 0.66, P = 0.04) but not to variation in heart rate or blood pressure. Stepwise multiple regression analysis indicated a respiratory frequency influence on SVV at the onset of ergometer cycling. Conclusion: The data provide evidence for a ventilatory influence on SVV at the onset of cycling exercise.
AB - Purpose: During cycling, the variation in cardiac stroke volume (SVV) is similar to that at rest. However, SVV may be influenced by ventilation at the start of cycling, e.g., by a Valsalva-like maneuver used to stabilize the body. This study evaluated the influence of ventilation on SV during initiation of cycling. Methods: Ten healthy recreationally physical active males (mean ± SD: age 26 ± 3 years, height 184 ± 9 cm, weight 85 ± 9 kg) cycled on an ergometer for four 30 s intervals at submaximal workloads while synchronizing ventilatory and cardiovascular variables derived from gas exchange and arterial pulse contour analysis, respectively. Results: At exercise onset, cardiac output increased by an instantaneous rise in heart rate and SV (P < 0.05). In contrast, blood pressure increased only after 15 s (P < 0.05), reflected in a decline in total peripheral resistance from exercise onset (P < 0.05). SVV was similar at rest (20 ± 6%) and during exercise (21 ± 5%) except for the first 5 s of exercise when a ~ 2.5-fold elevation (47 ± 6%; P < 0.05) was correlated to variation in respiratory frequency (= 0.71, P = 0.02) and tidal volume (R = 0.66, P = 0.04) but not to variation in heart rate or blood pressure. Stepwise multiple regression analysis indicated a respiratory frequency influence on SVV at the onset of ergometer cycling. Conclusion: The data provide evidence for a ventilatory influence on SVV at the onset of cycling exercise.
KW - Arterial blood pressure
KW - Breathing
KW - Cardiac output
KW - Exercise
KW - Total peripheral resistance
U2 - 10.1007/s00421-021-04772-8
DO - 10.1007/s00421-021-04772-8
M3 - Journal article
C2 - 34302541
AN - SCOPUS:85111126873
VL - 121
SP - 3061
EP - 3067
JO - European Journal of Applied Physiology
JF - European Journal of Applied Physiology
SN - 1439-6319
IS - 11
ER -
ID: 275944026