Enhanced insulin sensitivity after acute exercise is not associated with changes in high-molecular weight adiponectin concentration in plasma

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Enhanced insulin sensitivity after acute exercise is not associated with changes in high-molecular weight adiponectin concentration in plasma. / Magkos, Faidon; Mohammed, B Selma; Mittendorfer, Bettina.

In: European Journal of Endocrinology, Vol. 162, No. 1, 2010, p. 61-66.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Magkos, F, Mohammed, BS & Mittendorfer, B 2010, 'Enhanced insulin sensitivity after acute exercise is not associated with changes in high-molecular weight adiponectin concentration in plasma', European Journal of Endocrinology, vol. 162, no. 1, pp. 61-66. https://doi.org/10.1530/EJE-09-0756

APA

Magkos, F., Mohammed, B. S., & Mittendorfer, B. (2010). Enhanced insulin sensitivity after acute exercise is not associated with changes in high-molecular weight adiponectin concentration in plasma. European Journal of Endocrinology, 162(1), 61-66. https://doi.org/10.1530/EJE-09-0756

Vancouver

Magkos F, Mohammed BS, Mittendorfer B. Enhanced insulin sensitivity after acute exercise is not associated with changes in high-molecular weight adiponectin concentration in plasma. European Journal of Endocrinology. 2010;162(1):61-66. https://doi.org/10.1530/EJE-09-0756

Author

Magkos, Faidon ; Mohammed, B Selma ; Mittendorfer, Bettina. / Enhanced insulin sensitivity after acute exercise is not associated with changes in high-molecular weight adiponectin concentration in plasma. In: European Journal of Endocrinology. 2010 ; Vol. 162, No. 1. pp. 61-66.

Bibtex

@article{0541199fa04f4b2cb31cbc232d036b72,
title = "Enhanced insulin sensitivity after acute exercise is not associated with changes in high-molecular weight adiponectin concentration in plasma",
abstract = "Background and objective: The effect of exercise on the plasma concentration of high-molecular weight (HMW) adiponectin (i.e. the biologically active form of circulating adiponectin) and the possible role of HMW adiponectin in mediating the exercise-induced enhancement of insulin action are not known. The aim of this study was to evaluate the relationship between the post-exercise increase in insulin sensitivity and plasma HMW adiponectin concentration.Design and methods: We measured total and HMW adiponectin concentrations in plasma using an ELISA kit, and insulin sensitivity using the updated homeostasis model assessment of insulin sensitivity (HOMA2-IS) score in the basal, overnight fasted state, once approximately 12 h after a single bout of moderate-intensity endurance exercise and once after an equivalent period of rest, in 27 healthy men and women (age: 29+/-1 years and body mass index: 24.7+/-0.8 kg/m(2)).Results: The HOMA2-IS score was 18+/-7% greater after exercise than after rest (229+/-20 and 196+/-17 respectively; P=0.006), whereas the concentrations of total adiponectin (7.8+/-0.5 and 7.7+/-0.5 mg/l respectively; P=0.597) and HMW adiponectin (3.0+/-0.3 and 3.0+/-0.3 mg/l respectively; P=0.625) were not different. The exercise-induced change in HOMA2-IS score was not related to changes in total and HMW adiponectin concentrations (P>0.3).Conclusions: Changes in HMW adiponectin concentration are not involved in the acute exercise-induced enhancement of insulin action.",
keywords = "Adiponectin/blood, Adult, Blood Glucose/metabolism, Exercise/physiology, Female, Homeostasis/physiology, Humans, Insulin/blood, Insulin Resistance/physiology, Male, Time Factors",
author = "Faidon Magkos and Mohammed, {B Selma} and Bettina Mittendorfer",
note = "(Ekstern)",
year = "2010",
doi = "10.1530/EJE-09-0756",
language = "English",
volume = "162",
pages = "61--66",
journal = "European Journal of Endocrinology",
issn = "0804-4643",
publisher = "BioScientifica Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Enhanced insulin sensitivity after acute exercise is not associated with changes in high-molecular weight adiponectin concentration in plasma

AU - Magkos, Faidon

AU - Mohammed, B Selma

AU - Mittendorfer, Bettina

N1 - (Ekstern)

PY - 2010

Y1 - 2010

N2 - Background and objective: The effect of exercise on the plasma concentration of high-molecular weight (HMW) adiponectin (i.e. the biologically active form of circulating adiponectin) and the possible role of HMW adiponectin in mediating the exercise-induced enhancement of insulin action are not known. The aim of this study was to evaluate the relationship between the post-exercise increase in insulin sensitivity and plasma HMW adiponectin concentration.Design and methods: We measured total and HMW adiponectin concentrations in plasma using an ELISA kit, and insulin sensitivity using the updated homeostasis model assessment of insulin sensitivity (HOMA2-IS) score in the basal, overnight fasted state, once approximately 12 h after a single bout of moderate-intensity endurance exercise and once after an equivalent period of rest, in 27 healthy men and women (age: 29+/-1 years and body mass index: 24.7+/-0.8 kg/m(2)).Results: The HOMA2-IS score was 18+/-7% greater after exercise than after rest (229+/-20 and 196+/-17 respectively; P=0.006), whereas the concentrations of total adiponectin (7.8+/-0.5 and 7.7+/-0.5 mg/l respectively; P=0.597) and HMW adiponectin (3.0+/-0.3 and 3.0+/-0.3 mg/l respectively; P=0.625) were not different. The exercise-induced change in HOMA2-IS score was not related to changes in total and HMW adiponectin concentrations (P>0.3).Conclusions: Changes in HMW adiponectin concentration are not involved in the acute exercise-induced enhancement of insulin action.

AB - Background and objective: The effect of exercise on the plasma concentration of high-molecular weight (HMW) adiponectin (i.e. the biologically active form of circulating adiponectin) and the possible role of HMW adiponectin in mediating the exercise-induced enhancement of insulin action are not known. The aim of this study was to evaluate the relationship between the post-exercise increase in insulin sensitivity and plasma HMW adiponectin concentration.Design and methods: We measured total and HMW adiponectin concentrations in plasma using an ELISA kit, and insulin sensitivity using the updated homeostasis model assessment of insulin sensitivity (HOMA2-IS) score in the basal, overnight fasted state, once approximately 12 h after a single bout of moderate-intensity endurance exercise and once after an equivalent period of rest, in 27 healthy men and women (age: 29+/-1 years and body mass index: 24.7+/-0.8 kg/m(2)).Results: The HOMA2-IS score was 18+/-7% greater after exercise than after rest (229+/-20 and 196+/-17 respectively; P=0.006), whereas the concentrations of total adiponectin (7.8+/-0.5 and 7.7+/-0.5 mg/l respectively; P=0.597) and HMW adiponectin (3.0+/-0.3 and 3.0+/-0.3 mg/l respectively; P=0.625) were not different. The exercise-induced change in HOMA2-IS score was not related to changes in total and HMW adiponectin concentrations (P>0.3).Conclusions: Changes in HMW adiponectin concentration are not involved in the acute exercise-induced enhancement of insulin action.

KW - Adiponectin/blood

KW - Adult

KW - Blood Glucose/metabolism

KW - Exercise/physiology

KW - Female

KW - Homeostasis/physiology

KW - Humans

KW - Insulin/blood

KW - Insulin Resistance/physiology

KW - Male

KW - Time Factors

U2 - 10.1530/EJE-09-0756

DO - 10.1530/EJE-09-0756

M3 - Journal article

C2 - 19864294

VL - 162

SP - 61

EP - 66

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

SN - 0804-4643

IS - 1

ER -

ID: 290670949