Jørgen Wojtaszewski

Jørgen Wojtaszewski

Professor

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    ORCID: 0000-0001-8185-3408

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    1. Published

      Nitric oxide production is a proximal signaling event controlling exercise-induced mRNA expression in human skeletal muscle

      Steensberg, A., Keller, C., Hilling, T., Frøsig, C., Wojtaszewski, Jørgen F P, Pedersen, Bente Klarlund, Pilegaard, Henriette & Sander, M., 2007, In: The FASEB Journal. 21, 11, p. 2683-2694 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Opposite regulation of insulin sensitivity by dietary lipid versus carbohydrate excess

      Lundsgaard, Anne-Marie, Sjøberg, K. A., Høeg, L. D., Jeppesen, J., Jordy, A. B., Serup, A. K. L., Fritzen, Andreas Mæchel, Pilegaard, Henriette, Myrmel, L. S., Madsen, L., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2017, In: Diabetes. 66, 10, p. 2583-2595 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Optimizing hyaluronidase dose and plasmid DNA delivery greatly improves gene electrotransfer efficiency in rat skeletal muscle

      Åkerström, T., Vedel, K., Needham Andersen, J., Hojman, P., Kontou, E., Hellsten, Ylva & Wojtaszewski, Jørgen F P, Dec 2015, In: Biochemistry and Biophysics Reports. 4, p. 342-350 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Oral glucose ingestion attenuates exercise-induced activation of 5'-AMP-activated protein kinase in human skeletal muscle

      Åkerström, T., Birk, Jesper Bratz, Klein, D. K., Erikstrup, C., Plomgaard, P., Pedersen, Bente Klarlund & Wojtaszewski, Jørgen F P, 2006, In: Biochemical and Biophysical Research Communications. 342, 3, p. 949-955 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      PDH-E1alpha dephosphorylation and activation in human skeletal muscle during exercise: effect of intralipid infusion

      Pilegaard, Henriette, Birk, Jesper Bratz, Sacchetti, M., Mourtzakis, M., Hardie, D. G., Stewart, G., Neufer, P. D., Saltin, B., van Hall, Gerrit & Wojtaszewski, Jørgen F P, 2006, In: Diabetes. 55, 11, p. 3020-3027 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle

      Leick, L., Wojtaszewski, Jørgen F P, Johansen, S. T., Kiilerich, K., Comes, G., Hellsten, Ylva, Hidalgo, J. & Pilegaard, Henriette, 2008, In: American Journal of Physiology: Endocrinology and Metabolism. 294, 2, p. E463-E474 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      PGC-1alpha is required for training-induced prevention of age-associated decline in mitochondrial enzymes in mouse skeletal muscle

      Leick, L., Lyngby, S. S., Wojtaszewski, Jørgen F P, Wojtasewski, J. F. P. & Pilegaard, Henriette, 2010, In: Experimental Gerontology. 45, 5, p. 336-342 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      PGC-1alpha mediates exercise-induced skeletal muscle VEGF expression in mice

      Leick, L., Hellsten, Ylva, Fentz, J., Lyngby, S. S., Wojtaszewski, Jørgen F P, Hidalgo, J. & Pilegaard, Henriette, 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 1, p. E92-E103 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      PGC-1{alpha} increases PDH content but does not change acute PDH regulation in mouse skeletal muscle

      Kiilerich, K., Adser, H., Jakobsen, A. H., Pedersen, Per Amstrup, Hardie, D. G., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2010, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 299, 5, p. R1350-R1359 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      PGC-1α is required for AICAR induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle

      Leick, L., Fentz, J., Biensø, R. S., Knudsen, Jakob Grunnet, Jeppesen, J., Kiens, Bente, Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 3, p. E456-E465 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Partial rescue of in vivo insulin signalling in skeletal muscle by impaired insulin clearance in heterozygous carriers of a mutation in the insulin receptor gene

      Højlund, K., Wojtaszewski, Jørgen F P, Birk, J. B., Hansen, B. F., drb459, drb459 & Beck-Nielsen, H., 2006, In: Diabetologia. 49, 8, p. 1827-1837 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Perfused rat hindlimb is suitable for skeletal muscle glucose transport measurements

      Wojtaszewski, Jørgen F P, Jakobsen, A. B., Ploug, Thorkil & Richter, Erik A., 1998, In: American Journal of Physiology: Endocrinology and Metabolism. 274, 37, p. E184-E191 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Personalized phosphoproteomics identifies functional signaling

      Needham, E. J., Hingst, J. R., Parker, B. L., Morrison, K. R., Yang, G., Onslev, Johan Dejgaard, Kristensen, Jonas Møller, Højlund, K., Ling, N. X. Y., Oakhill, J. S., Richter, Erik A., Kiens, Bente, Petersen, J., Pehmøller, C., James, D. E., Wojtaszewski, Jørgen F P & Humphrey, S. J., 2022, In: Nature Biotechnology. 40, 4, p. 576-584 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. E-pub ahead of print

      Pharmacological activation of PDC flux reverses lipid-induced inhibition of insulin action in muscle during recovery from exercise

      Carl, Christian Strini, Jensen, M. M., Sjøberg, K. A., Constantin-Teodosiu, D., Hill, I. R., Kjøbsted, Rasmus, Greenhaff, P. L., Wojtaszewski, Jørgen F P, Richter, Erik A., Fritzen, Andreas Mæchel & Kiens, Bente, 2024, (E-pub ahead of print) In: Diabetes.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers

      Schnurr, T. M., Jørsboe, E., Chadt, A., Dahl-Petersen, I. K., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Springer, C., Bjerregaard, P., Brage, S., Pedersen, Oluf Borbye, Moltke, Ida, Grarup, Niels, Al-Hasani, H., Albrechtsen, Anders, Jørgensen, M. E. & Hansen, Torben, 2021, In: Diabetologia. 64, p. 1795-1804

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Physical inactivity affects skeletal muscle insulin signaling in a birth weight-dependent manner

      Mortensen, B., Friedrichsen, M., Andersen, Nicoline Resen, Alibegovic, A. C., Højbjerre, L., Sonne, M. P., Stallknecht, Bente Merete, Dela, Flemming, Wojtaszewski, Jørgen F P & Vaag, Allan, 2014, In: Journal of Diabetes and its Complications. 28, 1, p. 71-78 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models

      Viollet, B., Andreelli, F., Jørgensen, S. B., Perrin, C., Flamez, D., Mu, J., Wojtaszewski, Jørgen F P, Schuit, F. C., Birnbaum, M., Richter, Erik A., Burcelin, R. & Vaulont, S., 2003, In: Biochemical Society Transactions. 31, 1, p. 216-219

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction

      Jensen, Thomas Elbenhardt, Rose, A. J., Jørgensen, S. B., Brandt, N., Schjerling, P., Wojtaszewski, Jørgen F P & Richter, Erik A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 5, p. E1308-E1317 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Possible role of AS160 in post-exercise increased insulin sensitivity in human skeletal muscle

      Treebak, Jonas Thue, Kristensen, Jonas Møller, Frosig, C., Pehmoller, C., Hardie, D. G., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2008, In: Diabetes.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Post-exercise recovery for the endurance athlete with type 1 diabetes: a consensus statement

      Scott, S. N., Fontana, F. Y., Cocks, M., Morton, J. P., Jeukendrup, A., Dragulin, R., Wojtaszewski, Jørgen F P, Jensen, J., Castol, R., Riddell, M. C., Stettler, C. & Study of Integrative Biology of Exercise in Diabetes, S. O. I. B. O. E. I. D., 2021, In: The Lancet Diabetes & Endocrinology. 9, 5, p. 304-317 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    21. Published

      Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle

      Treebak, Jonas Thue, Frøsig, C., Pehmøller, C., Chen, S., Maarbjerg, S. J., Brandt, N., Mackintosh, C., Zierath, J. R., Hardie, D. G., Kiens, Bente, Richter, Erik A., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2009, In: Diabetologia. 52, 5, p. 891-900 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Predominant alpha2/beta2/gamma3 AMPK activation during exercise in human skeletal muscle

      Birk, Jesper Bratz & Wojtaszewski, Jørgen F P, 2006, In: Journal of Physiology. 577, 3, p. 1021-1032 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner

      Kjøbsted, Rasmus, Treebak, Jonas Thue, Fentz, J., Lantier, L., Viollet, B., Birk, Jesper Bratz, Schjerling, Peter, Björnholm, M., Zierath, Juleen R & Wojtaszewski, Jørgen F P, 2015, In: Diabetes. 64, 6, p. 2042-2055 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Prior exercise in humans redistributes intramuscular GLUT4 and enhances insulin-stimulated sarcolemmal and endosomal GLUT4 translocation

      Knudsen, Jonas Roland, Steenberg, D. E., Hingst, J. R., Hodgson, L. R., Henriquez-Olguín, Carlos, Li, Z., Kiens, Bente, Richter, Erik A., Wojtaszewski, Jørgen F P, Verkade, P. & Jensen, Thomas Elbenhardt, 2020, In: Molecular Metabolism. 39, 9 p., 100998.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Quantification of exercise-regulated ubiquitin signaling in human skeletal muscle identifies protein modification cross talk via NEDDylation

      Parker, B. L., Kiens, Bente, Wojtaszewski, Jørgen F P, Richter, Erik A. & James, D. E., 2020, In: F A S E B Journal. 34, 4, p. 5906-5916 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle

      Sylow, Lykke, Jensen, Thomas Elbenhardt, Kleinert, Maximilian, Højlund, K., Kiens, Bente, Wojtaszewski, Jørgen F P, Prats Gavalda, Clara, Schjerling, P. & Richter, Erik A., 2013, In: Diabetes. 62, 6, p. 1865-1875 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscle

      Frøsig, C., Roepstorff, C., Brandt, N., Maarbjerg, S. J., Birk, Jesper Bratz, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 296, 4, p. E787-E795 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes

      Højlund, K., Frystyk, J., Levin, K., Flyvbjerg, A., Wojtaszewski, Jørgen F P & Beck-Nielsen, H., 2006, In: Diabetologia. 49, 6, p. 1283-1291 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Reducing the mitochondrial oxidative burden alleviates lipid-induced insulin resistance in human skeletal muscle

      Fiorenza, Matteo, Onslev, J., Henriquez-Olguín, Carlos, Jensen, Thomas Elbenhardt, Wojtaszewski, Jørgen F P, Hostrup, Morten & Bangsbo, Jens, 12 Apr 2023, bioRxiv, p. 1-39, 39 p.

      Research output: Working paper › Preprint › Research

    30. Published

      Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle

      Wojtaszewski, Jørgen F P, MacDonald, C. S., Nielsen, J. N., Hellsten, Ylva, Hardie, D. G., Kemp, B. E., Kiens, Bente & Richter, Erik A., 2003, In: American Journal of Physiology: Endocrinology and Metabolism. 284, 4, p. E813-E822

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Regulation of PDH in human arm and leg muscles at rest and during intense exercise

      Kiilerich, K., Birk, Jesper Bratz, Damsgaard, R., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2008, In: American Journal of Physiology: Endocrinology and Metabolism. 294, 1, p. E36-E42 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation

      Fritzen, Andreas Mæchel, Madsen, A. L. B., Kleinert, Maximilian, Treebak, Jonas Thue, Lundsgaard, Anne-Marie, Jensen, Thomas Elbenhardt, Richter, Erik A., Wojtaszewski, Jørgen F P, Kiens, Bente & Frøsig, C., 2016, In: Journal of Physiology. 594, 3, p. 745-761 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Regulation of glycogen synthase activity and phosphorylation by exercise

      Nielsen, J. N. & Wojtaszewski, Jørgen F P, 2004, In: Proceedings of the Nutrition Society. 63, 2, p. 233-237 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Regulation of glycogen synthase kinase-3 in human skeletal muscle. Effects of food intake and bicycle exercise

      Wojtaszewski, Jørgen F P, Nielsen, P., Kiens, Bente & Richter, Erik A., 2001, In: Diabetes. 50, 2, p. 265-269 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Regulation of hormone sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise

      Roepstorff, C., Vistisen, B., Donsmark, M., Nielsen, J. N., Galbo, H., Green, K. A., Hardie, D. G., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2004, Regulation of lipid utilization in human skeletal muscle during exercise: Insights from studies on gender comparison and substrate availability. Roepstorff, C. (ed.). Copenhagen: Institut for Idræt, Københavns Universitet, p. 111-123

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    36. Published

      Regulation of hormone sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise

      Roepstorff, C., Vistisen, B., Donsmark, M., Nielsen, J. N., Galbo, H., Green, K. A., Hardie, D. G., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2004, In: Journal of Physiology. 560, 2, p. 551-562

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Regulation of muscle glucose transport during exercise

      Richter, Erik A., Wojtaszewski, Jørgen F P, Kristiansen, S., Daugaard, J. R., Nielsen, J. N., Derave, W. & Kiens, Bente, 2001, In: International Journal of Sport Nutrition & Exercise Metabolism. 11, Supplement 1, p. S71-S77 7 p.

      Research output: Contribution to journal › Review › Research

    38. Published

      Repeated prolonged whole-body low-intensity exercise: effects on insulin sensitivity and limb muscle adaptations

      Helge, Jørn Wulff, Overgaard, K., Damsgaard, R., Sørensen, K., Andersen, J. L., Dyrskog, S. E. U., Hermansen, K., Saltin, B. & Wojtaszewski, Jørgen F P, 2006, In: Metabolism - Clinical and Experimental. 55, 2, p. 217-223

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Role of 5'AMP-activated protein kinase in glycogen synthase activity and glucose utilization: insights from patients with McArdle's disease

      Nielsen, J. N., Wojtaszewski, Jørgen F P, Haller, R. G., Hardie, D. G., Kemp, B. E., Richter, Erik A. & Vissing, J., 2002, In: Journal of Physiology. 541, 3, p. 979-989

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Role of 5'AMP-activated protein kinase in skeletal muscle

      Treebak, Jonas Thue & Wojtaszewski, Jørgen F P, 2008, In: International Journal of Obesity. 32 Suppl. 4, p. S13-S17 5 p.

      Research output: Contribution to journal › Review › Research

    41. Published

      Role of AMP-activated protein kinase for regulating post-exercise insulin sensitivity

      Kjøbsted, Rasmus, Wojtaszewski, Jørgen F P & Treebak, Jonas Thue, 2016, AMP-activated Protein Kinase. Cordero, M. D. & Viollet, B. (eds.). Springer, p. 81-126 46 p. (E X S, Vol. 107).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    42. Published

      Role of AMPK in IL-6 release from isolated mouse skeletal muscle

      Glund, S., Treebak, Jonas Thue, Long, Y. C., Barrès, Romain, Viollet, B., Wojtaszewski, Jørgen F P & Zierath, Juleen R, 2008, In: Diabetologia.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise

      Jørgensen, S. B., Richter, Erik A. & Wojtaszewski, Jørgen F P, 2006, In: Journal of Physiology. 574, 1, p. 17-31 15 p.

      Research output: Contribution to journal › Review › Research

    44. Published

      Role of AMPKalpha2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle

      Jørgensen, S. B., Treebak, Jonas Thue, Viollet, B., Schjerling, P., Vaulont, S., Wojtaszewski, Jørgen F P & Richter, Erik A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 1, p. E331-E339 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport

      Cartee, G. D. & Wojtaszewski, Jørgen F P, 2007, In: Applied Physiology, Nutrition and Metabolism. 32, 3, p. 557-66 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Role of PGC-1{alpha} in exercise and fasting induced adaptations in mouse liver

      Haase, T. N., Jørgensen, S. R., Leick, L., Biensø, R. S., Kiilerich, K., Johansen, S., Nielsen, M. M., Wojtaszewski, Jørgen F P, Hidalgo, J., Pedersen, Per Amstrup & Pilegaard, Henriette, 2011, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 301, 5, p. R1501-R1509 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle

      Glund, S., Treebak, Jonas Thue, Long, Y. C., Barres, R., Viollet, B., Wojtaszewski, Jørgen F P & Zierath, J. R., 2009, In: Endocrinology. 150, 2, p. 600-606 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling

      Deshmukh, Atul Shahaji, Treebak, Jonas Thue, Long, Y. C., Viollet, B., Wojtaszewski, Jørgen F P & Zierath, J. R., 2008, In: Molecular Endocrinology. 22, 5, p. 1105-12 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Salbutamol increases leg glucose uptake and metabolic rate but not muscle glycogen resynthesis in recovery from exercise

      Onslev, J., Thomassen, Martin, Wojtaszewski, Jørgen F P, Bangsbo, Jens & Hostrup, Morten, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 3, p. e1193-e1203 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Serum is not necessary for prior pharmacological activation of AMPK to increase insulin sensitivity of mouse skeletal muscle

      Jørgensen, N. O., Wojtaszewski, Jørgen F P & Kjøbsted, Rasmus, 2018, In: International Journal of Molecular Sciences (Online). 19, 4, 11 p., 1201.

      Research output: Contribution to journal › Journal article › Research › peer-review

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