Jørgen Wojtaszewski
Professor
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Exercise signalling to glucose transport in skeletal muscle
Richter, Erik A., Nielsen, J. N., Jørgensen, S. B., Frøsig, C., Birk, J. B. & Wojtaszewski, Jørgen F P, 2004, In: Proceedings of the Nutrition Society. 63, 2, p. 211-216Research output: Contribution to journal › Journal article › Research › peer-review
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5'adenosinmonofosfataktiveret proteinkinase og livsstilssygdomme
Richter, Erik A., Kiens, Bente & Wojtaszewski, Jørgen F P, 2006, In: Ugeskrift for læger. 168, 9, p. 896-900 5 p.Research output: Contribution to journal › Journal article › Research
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Regulation of muscle glucose transport during exercise
Richter, Erik A., Wojtaszewski, Jørgen F P, Kristiansen, S., Daugaard, J. R., Nielsen, J. N., Derave, W. & Kiens, Bente, 2001, In: International Journal of Sport Nutrition & Exercise Metabolism. 11, Supplement 1, p. S71-S77 7 p.Research output: Contribution to journal › Review › Research
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Comment on Point: Counterpoint "Glucose phosphorylation is/is not a significant barrier to muscle glucose uptake by the working muscle"
Richter, Erik A., Rose, A. J., Wojtaszewski, Jørgen F P & Hargreaves, M., 2006, In: Journal of Applied Physiology. 101, 6, p. 1809 1 p.Research output: Contribution to journal › Comment/debate › Research
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Training effects on muscle glucose transport during exercise
Richter, Erik A., Kristiansen, S., Wojtaszewski, Jørgen F P, Daugaard, J. R., Asp, S., Hespel, P. J. L. & Kiens, Bente, 1998, Skeletal Muscle Metabolism in Exercise and Diabetes: Proceedings of the Copenhagen Muscle Research Centre Symposium on Regulation of Skeletal Muscle Metabolism, October 23-26, 1997, Copenhagen. Richter, E. A., Kiens, B., Galbo, H. & Saltin, B. (eds.). New York: Plenum Publishing Corporation, p. 107-116 10 p. (Advances in Experimental Medicine and Biology, Vol. 441).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Glucose transport and transporters in skeletal muscle
Richter, Erik A., Kristiansen, S., Wojtaszewski, Jørgen F P & Hundal, H. S., 1998, Biochemistry of Exercise X: The 10th international biochemistry of exercise conference, July 15-19, 1997, Sydney, Australia. Hargreaves, M. & Thompson, M. (eds.). Champaign, IL: Human Kinetics, p. 169-183 15 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Glucose, exercise and insulin: emerging concepts
Richter, Erik A., Derave, W. & Wojtaszewski, Jørgen F P, 2001, In: Journal of Physiology. 535, 2, p. 313-322 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Can exercise mimetics substitute for exercise?
Richter, Erik A., Kiens, Bente & Wojtaszewski, Jørgen F P, 2008, In: Cell Metabolism. 8, 2, p. 96-98 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise
Roepstorff, C., Halberg, N., Hillig, T., Saha, A. K., Ruderman, N. B., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2005, In: American Journal of Physiology: Endocrinology and Metabolism. 288, 1, p. E133-E142 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise
Roepstorff, C., Thiele, M., Hillig, T., Pilegaard, Henriette, Richter, Erik A., Wojtaszewski, Jørgen F P & Kiens, Bente, 2006, In: Journal of Physiology. 574, 1, p. 125-138 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of hormone sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise
Roepstorff, C., Vistisen, B., Donsmark, M., Nielsen, J. N., Galbo, H., Green, K. A., Hardie, D. G., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2004, Regulation of lipid utilization in human skeletal muscle during exercise: Insights from studies on gender comparison and substrate availability. Roepstorff, C. (ed.). Copenhagen: Institut for Idræt, Københavns Universitet, p. 111-123Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Regulation of hormone sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise
Roepstorff, C., Vistisen, B., Donsmark, M., Nielsen, J. N., Galbo, H., Green, K. A., Hardie, D. G., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2004, In: Journal of Physiology. 560, 2, p. 551-562Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of endurance exercise training on Ca2+ -calmodulin-dependent protein kinase II expression and signalling in skeletal muscle of humans
Rose, A. J., Frøsig, C., Kiens, Bente, Wojtaszewski, Jørgen F P & Richter, Erik A., 2007, In: Journal of Physiology. 583, 2, p. 785-795 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
Rung, J., Cauchi, S., Albrechtsen, A., Shen, L., Rocheleau, G., Cavalcanti-Proença, C., Bacot, F., Balkau, B., Belisle, A., Borch-Johnsen, K., Charpentier, G., Dina, C., Durand, E., Elliott, P., Hadjadj, S., Järvelin, M-R., Laitinen, J., Lauritzen, T., Marre, M., Mazur, A. & 20 others, , 2009, In: Nature Genetics. 41, 10, p. 1110-1115 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intact regulation of muscle expression and circulating levels of myokines in response to exercise in patients with type 2 diabetes
Sabaratnam, R., Pedersen, A. J. T., Kristensen, Jonas Møller, Handberg, A., Wojtaszewski, Jørgen F P & Højlund, K., Jun 2018, In: Physiological Reports. 6, 12, 12 p., e13723.Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise induction of key transcriptional regulators of metabolic adaptation in muscle is preserved in type 2 diabetes
Sabaratnam, R., Pedersen, A. J., Eskildsen, T. V., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P & Højlund, K., 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 10, p. 4909-4920 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Acute Exercise Increases GDF15 and Unfolded Protein Response/Integrated Stress Response in Muscle in Type 2 Diabetes
Sabaratnam, R., Kristensen, Jonas Møller, Pedersen, A. J. T., Kruse, R., Handberg, A., Wojtaszewski, Jørgen F P & Højlund, K., 2024, (E-pub ahead of print) In: The Journal of Clinical Endocrinology & Metabolism. p. 1-11Research output: Contribution to journal › Journal article › Research › peer-review
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Factors mediating exercise-induced organ crosstalk
Sabaratnam, R., Wojtaszewski, Jørgen F P & Højlund, K., 2022, In: Acta Physiologica. 234, 2, 20 p., e13766.Research output: Contribution to journal › Review › Research › peer-review
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Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers
Schnurr, T. M., Jørsboe, E., Chadt, A., Dahl-Petersen, I. K., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Springer, C., Bjerregaard, P., Brage, S., Pedersen, Oluf Borbye, Moltke, Ida, Grarup, Niels, Al-Hasani, H., Albrechtsen, Anders, Jørgensen, M. E. & Hansen, Torben, 2021, In: Diabetologia. 64, p. 1795-1804Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired leptin gene expression and release in cultured preadipocytes isolated from individuals born with low birth weight
Schultz, N. S., Broholm, C., Gillberg, L., Mortensen, B., Jørgensen, S. W., Schultz, H. S., Schéele, Camilla Charlotte Nielsen, Wojtaszewski, Jørgen F P, Pedersen, Bente Klarlund & Vaag, Allan, 2014, In: Diabetes. 63, 1, p. 111-121 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Post-exercise recovery for the endurance athlete with type 1 diabetes: a consensus statement
Scott, S. N., Fontana, F. Y., Cocks, M., Morton, J. P., Jeukendrup, A., Dragulin, R., Wojtaszewski, Jørgen F P, Jensen, J., Castol, R., Riddell, M. C., Stettler, C. & Study of Integrative Biology of Exercise in Diabetes, S. O. I. B. O. E. I. D., 2021, In: The Lancet Diabetes & Endocrinology. 9, 5, p. 304-317 14 p.Research output: Contribution to journal › Review › Research › peer-review
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Metabolic effect of adrenaline infusion in people with type 1 diabetes and healthy individuals
She, R., Suvitaival, T., Andersen, H. U., Hommel, E., Nørgaard, Kirsten, Wojtaszewski, Jørgen F P, Legido-Quigley, C. & Pedersen-Bjergaard, Ulrik, 2024, In: Diabetologia. 67, p. 1095–1106Research output: Contribution to journal › Journal article › Research › peer-review
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Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity
Shi, H., Munk, A., Nielsen, T. S., Daughtry, M. R., Larsson, L., Li, S., Høyer, K. F., Geisler, H. W., Sulek, K., Kjøbsted, R., Fisher, T., Andersen, M. M., Shen, Z., Hansen, U. K., England, E. M., Cheng, Z., Højlund, K., Wojtaszewski, J., Yang, X., Hulver, M. W. & 3 others, , 2018, In: Molecular Metabolism. 11, p. 160-177 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise increases human skeletal muscle insulin sensitivity via coordinated increases in microvascular perfusion and molecular signaling
Sjøberg, K. A., Frøsig, C., Kjøbsted, Rasmus, Sylow, Lykke, Kleinert, Maximilian, Betik, A. C., Shaw, C. S., Kiens, Bente, Wojtaszewski, Jørgen F P, Rattigan, S., Richter, Erik A. & McConell, G. K., 2017, In: Diabetes. 66, 6, p. 1501-1510 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A single bout of one-legged exercise to local exhaustion decreases insulin action in non-exercised muscle leading to decreased whole-body insulin action
Steenberg, D. E., Hingst, J. R., Birk, Jesper Bratz, Thorup, A., Kristensen, Jonas Møller, Sjøberg, K. A., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2020, In: Diabetes. 69, 4, p. 578-590 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise training reduces the insulin-sensitizing effect of acute exercise in human skeletal muscle
Steenberg, D. E., Jørgensen, N. B., Birk, Jesper Bratz, Sjøberg, K. A., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2019, In: Journal of Physiology. 597, 1, p. 89-103 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitric oxide production is a proximal signaling event controlling exercise-induced mRNA expression in human skeletal muscle
Steensberg, A., Keller, C., Hilling, T., Frøsig, C., Wojtaszewski, Jørgen F P, Pedersen, Bente Klarlund, Pilegaard, Henriette & Sander, M., 2007, In: The FASEB Journal. 21, 11, p. 2683-2694 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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5'-AMP activated protein kinase is involved in the regulation of myocardial ß-oxidative capacity in mice
Stride, N., Larsen, S., Treebak, Jonas Thue, Hansen, C. N., Hey-Mogensen, M., Speerschneider, T., Jensen, Thomas Elbenhardt, Jeppesen, J., Wojtaszewski, Jørgen F P, Richter, Erik A., Køber, Lars Valeur & Dela, Flemming, 22 Feb 2012, In: Frontiers in Physiology. 3, 7 p., 00033.Research output: Contribution to journal › Journal article › Research › peer-review
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Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle
Sylow, Lykke, Jensen, Thomas Elbenhardt, Kleinert, Maximilian, Højlund, K., Kiens, Bente, Wojtaszewski, Jørgen F P, Prats Gavalda, Clara, Schjerling, P. & Richter, Erik A., 2013, In: Diabetes. 62, 6, p. 1865-1875 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating follistatin and activin A and their regulation by insulin in obesity and type 2 diabetes
Sylow, Lykke, Vind, B. F., Kruse, R., Møller, P. M., Wojtaszewski, Jørgen F P, Richter, Erik A. & Højlund, K., 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 5, p. 1343-1354 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise regulation of glucose transport in skeletal muscle
Tatsuya, H., Wojtaszewski, Jørgen F P & Goodyear, L. J., 1997, In: American Journal of Physiology.. 273 (Endocrinol.Metab. 36), p. E1039-E1051Research output: Contribution to journal › Journal article › Research
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Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise
Thong, F. S. L., Derave, W., Kiens, Bente, Graham, T. E., Ursø, B., Wojtaszewski, Jørgen F P, Hansen, B. F. & Richter, Erik A., 2002, In: Diabetes. 53, 3, p. 583-590Research output: Contribution to journal › Journal article › Research › peer-review
Exercise and insulin cause GLUT-4 translocation in human skeletal muscle
Thorell, A., Hirshman, M. F., Nygren, J., Jorfeldt, L., Wojtaszewski, Jørgen F P, Dufresne, S. D., Horton, E. S., Ljungqvist, O. & Goodyear, L. J., 1999, In: American Journal of Physiology - Endocrinology and Metabolism. 277, 4 (40-4), p. E733-E741 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.
Treebak, Jonas Thue, Glund, S., Deshmukh, Atul Shahaji, Klein, D. K., Long, Y. C., Jensen, Thomas Elbenhardt, Jørgensen, S. B., Viollet, B., Andersson, L., Neumann, D., Wallimann, T., Richter, Erik A., Chibalin, A. V., Zierath, J. R. & Wojtaszewski, Jørgen F P, 2006, In: Diabetes. 55, 7, p. 2051-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AS160 phosphorylation is associated with activation of alpha(2)beta(2)gamma(1)- but not alpha(2)beta(2)gamma(3)-AMPK trimeric complex in skeletal muscle during exercise in humans
Treebak, Jonas Thue, Birk, Jesper Bratz, Rose, A. J., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2007, In: American Journal of Physiology-Endocrinology and Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
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Possible role of AS160 in post-exercise increased insulin sensitivity in human skeletal muscle
Treebak, Jonas Thue, Kristensen, Jonas Møller, Frosig, C., Pehmoller, C., Hardie, D. G., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2008, In: Diabetes.Research output: Contribution to journal › Journal article › Research › peer-review
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A-769662 activates AMPK {beta}1-containing complexes but induces glucose uptake through a PI3 kinase-dependent pathway in mouse skeletal muscle
Treebak, Jonas Thue, Birk, Jesper Bratz, Hansen, B. F., Olsen, G. S. & Wojtaszewski, Jørgen F P, 2009, In: American Journal of Physiology: Cell Physiology. 297, 4, p. C1041-C1052 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 in human skeletal muscle
Treebak, Jonas Thue, Pehmøller, C., Kristensen, Jonas Møller, Kjøbsted, Rasmus, Birk, Jesper Bratz, Schjerling, Peter, Richter, Erik A., Goodyear, L. J. & Wojtaszewski, Jørgen F P, 2014, In: Journal of Physiology. 592, 2, p. 351-375 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle
Treebak, Jonas Thue, Frøsig, C., Pehmøller, C., Chen, S., Maarbjerg, S. J., Brandt, N., Mackintosh, C., Zierath, J. R., Hardie, D. G., Kiens, Bente, Richter, Erik A., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2009, In: Diabetologia. 52, 5, p. 891-900 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of 5'AMP-activated protein kinase in skeletal muscle
Treebak, Jonas Thue & Wojtaszewski, Jørgen F P, 2008, In: International Journal of Obesity. 32 Suppl. 4, p. S13-S17 5 p.Research output: Contribution to journal › Review › Research
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Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle
Treebak, Jonas Thue, Taylor, E. B., Witczak, C. A., An, D., Toyoda, T., Koh, H., Xie, J., Feener, E. P., Wojtaszewski, Jørgen F P, Hirshman, M. F. & Goodyear, L. J., 2010, In: American Journal of Physiology: Cell Physiology. 298, 2, p. C377-C385 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AS160 phosphorylation is associated with activation of alpha2beta2gamma1 - but not alpha2beta2gamma3 -AMPK trimeric complex in skeletal muscle during exercise in humans
Treebak, Jonas Thue, Birk, Jesper Bratz, Rose, A. J., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 3, p. E715-E722 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle
Vendelbo, M., Clasen, B. F. F., Treebak, Jonas Thue, Møller, L., Krusenstjerna-Hafstrøm, T., Madsen, M., Nielsen, Thomas Svava, Stødkilde-Jørgensen, H., Pedersen, S. B., Jørgensen, J. O. L., Goodyear, L. J., Wojtaszewski, Jørgen F P, Møller, N. & Jessen, N., 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 302, 2, p. E190-E200 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 minutes after a single bout of exercise
Vendelbo, M. H., Møller, A. B., Treebak, Jonas Thue, Gormsen, L. C., Goodyear, L. J., Wojtaszewski, Jørgen F P, Jorgensen, J. O. L., Møller, N. & Jessen, N., 2014, In: Journal of Applied Physiology. 117, 3, p. 289-296 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of age and unilateral leg immobilization for 2 weeks on substrate utilization during moderate intensity exercise in human skeletal muscle
Vigelsø, A., Gram, M., Dybboe, R., Kuhlman, A. B., Prats Gavalda, Clara, Greenhaff, P. L., Constantin-Teodosiu, D., Birk, Jesper Bratz, Wojtaszewski, Jørgen F P, Dela, Flemming & Helge, Jørn Wulff, 2016, In: Journal of Physiology. 594, 8, p. 2339-2358 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperglycaemia normalises insulin action on glucose metabolism but not the impaired activation of AKT and glycogen synthase in the skeletal muscle of patients with type 2 diabetes
Vind, B. F., Birk, Jesper Bratz, Vienberg, S. G., Andersen, B., Beck-Nielsen, H., Wojtaszewski, Jørgen F P & Højlund, K., 2012, In: Diabetologia. 55, 5, p. 1435-1445 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training
Vind, B. F., Pehmøller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Hey-Mogensen, M., Beck-Nielsen, H., Zierath, J. R., Wojtaszewski, Jørgen F P & Højlund, K., 2011, In: Diabetologia. 54, 1, p. 157-167 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired Insulin-Mediated Phosphorylation of Skeletal Muscle TBC1D4 at Multiple Sites in Type 2 Diabetes. Effect of Endurance Training on TBC1D4 Protein and Phosphorylation
Vind, B. F., Pehmoller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Hey-Mogensen, M., Beck-Nielsen, H., Wojtaszewski, Jørgen F P & Hojlund, K., 2009, In: Diabetes.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models
Viollet, B., Andreelli, F., Jørgensen, S. B., Perrin, C., Flamez, D., Mu, J., Wojtaszewski, Jørgen F P, Schuit, F. C., Birnbaum, M., Richter, Erik A., Burcelin, R. & Vaulont, S., 2003, In: Biochemical Society Transactions. 31, 1, p. 216-219Research output: Contribution to journal › Journal article › Research › peer-review
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The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity
Viollet, B., Andreelli, F., Jørgensen, S. B., Perrin, C., Geloen, A., Flamez, D., Mu, J., Lenzner, C., Baud, O., Bennoun, M., Gomas, E., Nicolas, G., Wojtaszewski, Jørgen F P, Kahn, A., Carling, D., Schuit, F. C., Birnbaum, M. J., Richter, Erik A., Burcelin, R. & Vaulont, S., 2003, In: Journal of Clinical Investigation. 111, 1, p. 91-98 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function
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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
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Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model
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